Protein Alignment Cyp12b2 and Cyp6a2

DIOPT Version :10

• Sequence 1: NP_611370.2
• Gene: Cyp12b2 / 37163
• FlyBaseID: FBgn0034387
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_523628.1
• Gene: Cyp6a2 / 35587
• FlyBaseID: FBgn0000473
• Length: 506
• Species: Drosophila melanogaster
• Alignment Length: 571
• Identity: 128/571 - (22%)
• Similarity: 213/571 - (37%)
• Gaps: 176/571 - (30%)

  Fly    47 WQQARSFGEIPGPSLLRMLSFFMPGGALRNTNLIQMNRLMREMYGDIYCIPGMMGKPNAVFTYNP 111
            |.:.....:.|.|....|:.|             :.||:|.:.:.|.|
  Fly    26 WNRRGVPHDAPHPLYGNMVGF-------------RKNRVMHDFFYDYY----------------- 60

  Fly   112 DDFEMTYRNEGVWPIRIGLESLNYYRKIHRPDVF------------KGVGGLASDQGQ------- 157
                ..||..| :|. :|.    |:  :|:|..|            |.....| |:||
  Fly    61 ----NKYRKSG-FPF-VGF----YF--LHKPAAFIVDTQLAKNILIKDFSNFA-DRGQFHNGRDD 112

  Fly   158 ------------EWADIRNKVNPVL----MKVQNVRQNLPQLDQISKEFIDKLETQRNP------ 200
                        :|.|:|.::.|..    ||..     .|.:.::|:||: |:.|::.|
  Fly   113 PLTQHLFNLDGKKWKDMRQRLTPTFTSGKMKFM-----FPTVIKVSEEFV-KVITEQVPAAQNGA 171

  Fly   201 -----------------------ETHTLTT---DFHNQ-------------LKMWAFESISFVAL 226
                                   |.:||.|   ||...             |.|:.|   ||..|
  Fly   172 VLEIKELMARFTTDVIGTCAFGIECNTLRTPVSDFRTMGQKVFTDMRHGKLLTMFVF---SFPKL 233

  Fly   227 NTRMGLLSDNPDPNADRLAKHMRDFFNYSFQFDVQPSIWTFYKTAGFKKFLKTYDNITDITSNYI 291
            .:|:.:             :.|.:..:..|...|..:| ...:...||:        .|..:..|
  Fly   234 ASRLRM-------------RMMPEDVHQFFMRLVNDTI-ALRERENFKR--------NDFMNLLI 276

  Fly   292 ETAMRGFGKNDDGKTKCVLEQLLEHNKKVAVTMVMDMLMAGIDTTSSACLTILYHLARNPSKQEK 356
            |...:|....|:|:   |:|. ::..:..|...|  ..:||.:|:||.....||.||:|...|::
  Fly   277 ELKQKGRVTLDNGE---VIEG-MDIGELAAQVFV--FYVAGFETSSSTMSYCLYELAQNQDIQDR 335

  Fly   357 LRRELLRILPTTKDSLTDQNTKNMPYLRACIKEGLRITSITPGNFRITPKDLVLSGYQ---VPRG 418
            ||.|:..:|...:..||.::.|.|.||...|.|.||:.::.|...|....|.|:.|::   :.:|
  Fly   336 LRNEIQTVLEEQEGQLTYESIKAMTYLNQVISETLRLYTLVPHLERKALNDYVVPGHEKLVIEKG 400

  Fly   419 TGVLMGVLELSNDDKYFAQSSEFIPERWLKSDLAPDIQACPAARTRNPFVYLPFGFGPRTCIGKR 483
            |.|::.......|:..:.....|.|||:....:|          .|....:||||.|||.|||.|
  Fly   401 TQVIIPACAYHRDEDLYPNPETFDPERFSPEKVA----------ARESVEWLPFGDGPRNCIGMR 455

  Fly   484 IAELEIETLLVRLLRSYKVSW--LPETPIEYE-STIILSPCGDIRFKLEPV 531
            ..:::....|.:::..::||.  ..|.|::|. .:|:|...|.|..::|.:
  Fly   456 FGQMQARIGLAQIISRFRVSVCDTTEIPLKYSPMSIVLGTVGGIYLRVERI 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12b2	NP_611370.2	CYP24A1-like	87..525	CDD:410677	118/523 (23%)
Cyp6a2	NP_523628.1	CYP6-like	69..500	CDD:410679	113/485 (23%)