Protein Alignment Cyp12b2 and Cyp4e3

DIOPT Version :10

• Sequence 1: NP_611370.2
• Gene: Cyp12b2 / 37163
• FlyBaseID: FBgn0034387
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_523527.1
• Gene: Cyp4e3 / 34291
• FlyBaseID: FBgn0015035
• Length: 526
• Species: Drosophila melanogaster
• Alignment Length: 480
• Identity: 119/480 - (24%)
• Similarity: 200/480 - (41%)
• Gaps: 90/480 - (18%)

  Fly    81 QMNRLMREMYGDIYCIPGMMGKPNAV---------------FTYNPDDFEMTYRNEGVWPIRIGL 130
            |..:|::|..|.. .:| ::|..|.:               :.|..|:|..       |   ||.
  Fly    25 QRRQLLKEFNGPT-PVP-ILGNANRIGKNPAEILSTFFDWWYDYGKDNFLF-------W---IGY 77

  Fly   131 ES-------------LNYYRKIHRPDVF----KGVG-GLASDQGQEWADIRNKVNPVLMKVQNVR 177
            .|             ||..:.|.:..::    ..:| ||.:..|.:|...|..:.|...  .|:.
  Fly    78 SSHIVMTNPKQLEYILNSQQLIQKSTIYDLLHPWLGHGLLTSFGSKWHKHRKMITPSFH--FNIL 140

  Fly   178 QNLPQ-LDQISKEFIDKLETQRNPETHTLTTDFHNQLKMWAFESISFVALNTRMGLLSDNPDPNA 241
            |:..: :::.|.:|:.:|:.....:|   ..||.........:    |..:|.||:..:..:...
  Fly   141 QDFHEVMNENSAKFMTQLKKASAGDT---IIDFQEHANYLTLD----VICDTAMGVPINAMEQRD 198

  Fly   242 DRLAKHMRDF-FNYSFQ--FDVQPSIWTFYKTAGFKKFLKTYDNITDITSNYIET---AMRGFGK 300
            ..:.:..||. :|.:.:  ...:.|...|..|..|..:.||...:.|.|.:.||.   |::..|.
  Fly   199 SSIVQAFRDMCYNINMRAFHPFKRSNRVFSLTPEFSAYQKTLKTLQDFTYDIIEKRVYALQNGGS 263

  Fly   301 NDD------GKTKCVLEQLLEH-------NKKVAVTMVMDMLMAGIDTTSSACLTILYHLARNPS 352
            .:|      .|....|:.||..       .::.....|...:..|.|||:|.....:|.|:|:|.
  Fly   264 KEDHDPSLPRKKMAFLDTLLSSTIDGRPLTRQEIYEEVSTFMFEGHDTTTSGVSFSVYLLSRHPD 328

  Fly   353 KQEKLRRELLRILPTTKD-SLTDQNTKNMPYLRACIKEGLRITSITPGNFRITPKDLVLSGYQVP 416
            .|.||.||...::....: |::.|....|.||...|||..|:....|...|...||..::|..||
  Fly   329 VQRKLYREQCEVMGHDMNRSVSFQEIAKMKYLDLFIKEAQRVYPSVPFIGRYCDKDYDINGSIVP 393

  Fly   417 RGTGVLMGVLELSNDDKYFAQSSEFIPERWLKSDLAPDIQACPAARTRNPFVYLPFGFGPRTCIG 481
            :||.:.:.::.|..:|:.|.....|.|||:.:..        ||     ||.||||..|||.|||
  Fly   394 KGTTLNLALILLGYNDRIFKDPHHFRPERFEEEK--------PA-----PFEYLPFSAGPRNCIG 445

  Fly   482 KRIAELEIETLLVRLLRSYKVSWLP 506
            ::.|.||::|::.:::||::|  ||
  Fly   446 QKFALLELKTVISKVVRSFEV--LP 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12b2	NP_611370.2	CYP24A1-like	87..525	CDD:410677	117/474 (25%)
Cyp4e3	NP_523527.1	CYP4	68..519	CDD:410721	111/435 (26%)