Protein Alignment Cyp12b2 and Cyp4ac1

DIOPT Version :10

• Sequence 1: NP_611370.2
• Gene: Cyp12b2 / 37163
• FlyBaseID: FBgn0034387
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_608916.1
• Gene: Cyp4ac1 / 33754
• FlyBaseID: FBgn0031693
• Length: 509
• Species: Drosophila melanogaster
• Alignment Length: 519
• Identity: 122/519 - (23%)
• Similarity: 207/519 - (39%)
• Gaps: 123/519 - (23%)

  Fly    69 MPGGALRNTNLIQMN-------RLMRE--------------MYGDIYCIPGMMGKPNAVFTYNPD 112
            |||......||..:|       ..:||              :|..:|         |.|   .|:
  Fly    50 MPGKTRFGNNLDILNFTPASVFNFVRESTAKAKGQNYLWYFLYAPMY---------NVV---RPE 102

  Fly   113 DFEMTYRNEGVWPIRIGLESLNYYRKIHRPDVFKGVGGLASDQGQEWADIRNKVNPVLMKVQNVR 177
            :.|..:::       ..|.:.|...::.||  |.|.|.|.|.. .:|...|..:.|...  .||.
  Fly   103 EAEEVFQS-------TKLITKNVVYELIRP--FLGDGLLISTD-HKWHSRRKALTPAFH--FNVL 155

  Fly   178 QN-LPQLDQISKEFIDKLETQRNPETHTLTTDFHNQLKMWAFESISFVALNTRMGLLSDNPDPNA 241
            |: |....:..|:|::.||...:.|     .:.:..:..:...:|...||..:   |.|..:.|.
  Fly   156 QSFLGIFKEECKKFLNVLEKNLDAE-----LELNQVIPPFTLNNICETALGVK---LDDMSEGNE 212

  Fly   242 DRLAKHMRD------------FFNYSFQFDVQPSIWTFYKTAGFKKFLKTYDNITDITSNYIETA 294
            .|.|.|..:            ::|           |.|:....::|.|:....:.|.:|..||..
  Fly   213 YRKAIHAIEEVLIQRVCNPLMYYN-----------WYFFVYGDYRKHLQNLRIVHDFSSRIIERK 266

  Fly   295 MRGFGKNDDGKTKCVLEQLLEHNKKVAVTMVMDMLMA----------------------GIDTTS 337
            .:.|.:...|:..       |..:|....| :|.|:|                      |.||||
  Fly   267 RQQFQQKQLGEVD-------EFGRKQRYAM-LDTLLAAEADGQIDHQGICDEVNTFMFEGYDTTS 323

  Fly   338 SACLTILYHLARNPSKQEKLRRELLRILPTTKDSLTDQNTKNMPYLRACIKEGLRITSITPGNFR 402
            :..:..|..||.:...|:|...| :..||...|.::......:.||...|||.||:....|...|
  Fly   324 TCLIFTLLMLALHEDVQKKCYEE-VENLPEDSDDISMFQFNKLVYLECVIKESLRMFPSVPFIGR 387

  Fly   403 ITPKDLVLSGYQVPRGTGVLMGVLELSNDDKYFAQSSEFIPERWLKSDLAPDIQACPAARTRNPF 467
            ...::.|::|..:|:.|.:.:.:.::..|.::|.:...|.|:|:|..:..          .|:||
  Fly   388 QCVEETVVNGMVMPKDTQISIHIYDIMRDPRHFPKPDLFQPDRFLPENTV----------NRHPF 442

  Fly   468 VYLPFGFGPRTCIGKRIAELEIETLLVRLLRSYKVSWLPETPIE---YESTIILSPCGDIRFKL 528
            .|:||..|.|.|||::.|.||::.||..::|::|:  ||.|.:|   :|:.|:|....:|:.||
  Fly   443 AYVPFSAGQRNCIGQKFAILEMKVLLAAVIRNFKL--LPATQLEDLTFENGIVLRTQENIKVKL 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12b2	NP_611370.2	CYP24A1-like	87..525	CDD:410677	113/489 (23%)
Cyp4ac1	NP_608916.1	CYP4	83..502	CDD:410721	112/482 (23%)