Protein Alignment Cyp12b2 and Cyp18a1

DIOPT Version :10

• Sequence 1: NP_611370.2
• Gene: Cyp12b2 / 37163
• FlyBaseID: FBgn0034387
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_523403.2
• Gene: Cyp18a1 / 32858
• FlyBaseID: FBgn0010383
• Length: 538
• Species: Drosophila melanogaster
• Alignment Length: 540
• Identity: 115/540 - (21%)
• Similarity: 220/540 - (40%)
• Gaps: 129/540 - (23%)

  Fly    51 RSFGEI----PGPSLLRMLSFFMPGGALRNTNLIQMNRLMREMYGDIYCIPGMMGKPNAVFTYNP 111
            |::.|:    |||..|.::.:.:..|:.::|..::    :.:.||.::..     :..:..|...
  Fly    45 RNYRELRKLPPGPWGLPVIGYLLFMGSEKHTRFME----LAKQYGSLFST-----RLGSQLTVVM 100

  Fly   112 DDFEM---TYRNEGVW--PIRIGLESLNYYRKIHRPDVFKGVGGLASDQGQEWADIRNKVNPVLM 171
            .|::|   .:|.|...  |....:::||.|             |:.:..|:.|.|.|..::..|.
  Fly   101 SDYKMIRECFRREEFTGRPDTPFMQTLNGY-------------GIINSTGKLWKDQRRFLHDKLR 152

  Fly   172 K-----VQNVRQNLPQ--LDQISKEFIDKLETQRNPETHTLTTDFHNQLKMWAFESISFVALNTR 229
            :     :.|.:|.:.:  :.:: .|||..|......     ..|....:.:.....|..:.::||
  Fly   153 QFGMTYMGNGKQQMQKRIMTEV-HEFIGHLHASDGQ-----PVDMSPVISVAVSNVICSLMMSTR 211

  Fly   230 MGLLSDNPDPNADR----LAKHMRDF-----FNYSFQFDVQPSIWT--------------FYKTA 271
            ..:    .||...|    :.:.||.|     .:|.......|||.|              ||:..
  Fly   212 FSI----DDPKFRRFNFLIEEGMRLFGEIHTVDYIPTMQCFPSISTAKNKIAQNRAEMQRFYQDV 272

  Fly   272 GFKKFLKTYD--NITDITSNY---IETAMRGFGKND---DGKTKCVLEQLLEHNKKVAVTMVMDM 328
             .....:::|  ||.|:...|   ||.| :..|.:.   |||         .|.::: |.:::|:
  Fly   273 -IDDHKRSFDPNNIRDLVDFYLCEIEKA-KAEGTDAELFDGK---------NHEEQL-VQVIIDL 325

  Fly   329 LMAGIDTTSSACLTILYHLARNPSKQEKLRRELLRI-----LPTTKDSLTDQNTKNMPYLRACIK 388
            ..||::|..:..|.|...:.|||.:..:::.||.::     |||.:|      .:.:|...:.|.
  Fly   326 FSAGMETIKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIED------LQYLPITESTIL 384

  Fly   389 EGLRITSITPGNFRITP-KDLVLSGYQVPRGTGVLMGVLELSNDDKYFAQSSEFIPERWLKSDLA 452
            |.:|.:||.|.....:| :|:.|:||.:|.|:.|:..:..:..|...:.:..||.|.|::.::
  Fly   385 ESMRRSSIVPLATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTE-- 447

  Fly   453 PDIQACPAARTRNPFVYLPFGFGPRTCIGKRIAELEIETLLVRLLRSYKVSWLPE---------- 507
                    .:.|.|..::|||.|.|.|:|..:|.:|:.......:..:.:: |||
  Fly   448 --------GKVRKPEYFIPFGVGRRMCLGDVLARMELFLFFASFMHCFDIA-LPEGQPLPSLKGN 503

  Fly   508 -----TPIEYESTIILSPCG 522
                 ||..::..:...|.|
  Fly   504 VGATITPESFKVCLKRRPLG 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12b2	NP_611370.2	CYP24A1-like	87..525	CDD:410677	107/500 (21%)
Cyp18a1	NP_523403.2	CYP306A1-like	85..515	CDD:410745	104/486 (21%)