Protein Alignment Cyp12b2 and Cyp311a1

DIOPT Version :10

• Sequence 1: NP_611370.2
• Gene: Cyp12b2 / 37163
• FlyBaseID: FBgn0034387
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_572780.3
• Gene: Cyp311a1 / 32170
• FlyBaseID: FBgn0030367
• Length: 483
• Species: Drosophila melanogaster
• Alignment Length: 518
• Identity: 132/518 - (25%)
• Similarity: 209/518 - (40%)
• Gaps: 111/518 - (21%)

  Fly    46 KWQQARSFGEIPGPSLLRMLSFFMPGGALRNTNLIQMNRLMREMYGDIYCIPGMMGKPNAVFTYN 110
            ||...|....:|||     .:|.:.|.|       ||...:|..|  |:          .|||..
  Fly    19 KWTLLRLGSSLPGP-----WAFPLLGNA-------QMVGKLRPEY--IF----------LVFTEL 59

  Fly   111 PDDFEMTYRNEGVWPIRIG------LESLNYYRK-IHRPDVFKG---------VG-GLASDQGQE 158
            .|.|..|||      :|:|      |.|....|: :|.|.:.|.         :| ||....|..
  Fly    60 RDRFGATYR------LRLGPQLWVFLHSAEETRQALHDPTLRKADTFMQLEPLIGNGLLISHGAH 118

  Fly   159 WADIRNKVNPVLMKVQNVRQNLPQLDQISKEFIDKLETQRNPETHTLTTDFHNQLKMWAFESIS- 222
            |...|..:.|. .:.|.:|...|.:....:..:.:|...|.                 ||..::
  Fly   119 WTRQRRLLTPA-FQPQLLRSFAPAIGGHVERLVGRLGATRG-----------------AFLEVTE 165

  Fly   223 --FVAL-----NTRMGLLSDNPDPNADRLAKHMRDFFNYSFQFDVQP---SIWTFYKTAGFKKFL 277
              |..|     :|.||...|....:...:.:.........|:..:.|   |.|.|.:|    :..
  Fly   166 PLFACLLDAIVDTSMGAQLDTQSVDHSPIIQAFHLSSKLLFKRMINPLLSSDWIFQRT----QLW 226

  Fly   278 KTYDNITDITSNYIETAMRGFGK------NDDGKTKCVLEQLL-------EHNKKVAVTMVMDML 329
            :..|....:..:.:|:.:....|      ...|:...:|:.||       ..:::.....:...:
  Fly   227 RDLDEQLQVIHSQMESVIEKRAKELLDMGEPAGRAHNLLDTLLLAKFEGQSLSRREIRDEINTFV 291

  Fly   330 MAGIDTTSSACLTILYHLARNPSKQEKLRRELLRILPTTKDSLTDQNTKN-MPYLRACIKEGLRI 393
            .||:|||::|...:||.||:.|..|.:||:||..:   ..|..||.:..| :|||.|.|||.||:
  Fly   292 FAGVDTTTAAMSFVLYALAKFPETQTRLRKELQDV---ALDETTDLDALNGLPYLEALIKEVLRL 353

  Fly   394 TSITPGNFRITPKDLVLSGYQVPRGTGVLMGVLELSNDDKYFAQSSEFIPERWLKSD--LAPDIQ 456
            .:|.|...|.|.:...:.|.....|..:.:.:..|::|.:|:.....|.|||||..|  :||
  Fly   354 YTIVPTTGRQTTQSTEIGGRTYCAGVTLWINMYGLAHDKEYYPDPYAFKPERWLPEDGAVAP--- 415

  Fly   457 ACPAARTRNPFVYLPFGFGPRTCIGKRIAELEIETLLVRLLRSYKVSWLPE-TPIEYESTIIL 518
              ||      |.|:||..||..|||:|.:.|.::.|..||:|.:::...|| .|:..|:.::|
  Fly   416 --PA------FSYIPFSGGPHVCIGRRYSLLLMKLLTARLVREFQMELSPEQAPLRLEAQMVL 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12b2	NP_611370.2	CYP24A1-like	87..525	CDD:410677	121/477 (25%)
Cyp311a1	NP_572780.3	cytochrome_P450	64..478	CDD:477761	113/449 (25%)