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Protein Alignment Cyp12b2 and Cyp27a1

DIOPT Version :10

Sequence 1:	NP_611370.2	Gene:	Cyp12b2 / 37163	FlyBaseID:	FBgn0034387	Length:	535	Species:	Drosophila melanogaster
Sequence 2:	NP_849178.2	Gene:	Cyp27a1 / 301517	RGDID:	727915	Length:	533	Species:	Rattus norvegicus

Alignment Length:	490	Identity:	143/490 - (29%)
Similarity:	231/490 - (47%)	Gaps:	45/490 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 RSFGEIPGPSLLRML-SFFMPGGALRNTNLIQMNRLMREMYGDIYCIPGMMGKPNAVFTYNPDDF 114
            ||..|:|||..||.| ..|:.|..|   :|.::..|.:..||.::..  ..|....|...:....
  Rat    57 RSLAELPGPGTLRFLFQLFLRGYVL---HLHELQALNKAKYGPMWTT--TFGTRTNVNLASAPLL 116

  Fly   115 EMTYRNEGVWPIRIGLESLNYYRKIHRPDVFKGVG-GLASDQGQEWADIRNKVNPVLMKVQNVRQ 178
            |...|.||.:|||..:|..    |.||.  .||:. |:...|||:|..:|:.:|..::|......
  Rat   117 EQVMRQEGKYPIRDSMEQW----KEHRD--HKGLSYGIFITQGQQWYHLRHSLNQRMLKPAEAAL 175

  Fly   179 NLPQLDQISKEFIDKLETQRNPE-THTLTTDFHNQLKMWAFESISFVALNTRMGLLSDNPDPNAD 242
            ....|:::..:||.:|:..|... :.....|..:.|...|.|:|.::....|:|.|..:...:..
  Rat   176 YTDALNEVISDFIARLDQVRTESASGDQVPDVAHLLYHLALEAICYILFEKRVGCLEPSIPEDTA 240

  Fly   243 RLAKHMRDFFNYSFQFDVQPSIWTFYKTAGFKKFLKTYDNITDITSNY-------IETAMRGFGK 300
            ...:.:...|..|......|. |:......:|:::..:|||.......       ||..::..|.
  Rat   241 TFIRSVGLMFKNSVYVTFLPK-WSRPLLPFWKRYMNNWDNIFSFGEKMIHQKVQEIEAQLQAAGP 304

  Fly   301 ND---DGKTKCVL-EQLLEHNKKVAVTMVMDMLMAGIDTTSSACLTILYHLARNPSKQEKLRREL 361
            :.   .|....:| ::||...:.|..  ..::::||:||||:.....||||::||..||.|.:|:
  Rat   305 DGVQVSGYLHFLLTKELLSPQETVGT--FPELILAGVDTTSNTLTWALYHLSKNPEIQEALHKEV 367

  Fly   362 LRILPTTKDSLTDQNT--KNMPYLRACIKEGLRITSITPGNFR-ITPKDLVLSGYQVPRGTGVLM 423
            ..::|..|   ..||.  .:||.|:|.|||.||:..:.|.|.| ||.|:..::|:..|:.|..::
  Rat   368 TGVVPFGK---VPQNKDFAHMPLLKAVIKETLRLYPVVPTNSRIITEKETEINGFLFPKNTQFVL 429

  Fly   424 GVLELSNDDKYFAQSSEFIPERWL--KSDLAPDIQACPAARTRNPFVYLPFGFGPRTCIGKRIAE 486
            ....:|.|...|.:...|.|.|||  :.|....||        :||..:|||:|.|:|:|:||||
  Rat   430 CHYVVSRDPSVFPEPESFQPHRWLRKREDDNSGIQ--------HPFGSVPFGYGVRSCLGRRIAE 486

  Fly   487 LEIETLLVRLLRSYKVSWLPET-PIEYESTIILSP 520
            ||::.||.||::.|:|...|.. .::..|.|:|.|
  Rat   487 LEMQLLLSRLIQKYEVVLSPGMGEVKSVSRIVLVP 521

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.