Protein Alignment Cyp12b2 and Cyp12d1-d

DIOPT Version :9

• Sequence 1: NP_611370.2
• Gene: Cyp12b2 / 37163
• FlyBaseID: FBgn0034387
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_995812.1
• Gene: Cyp12d1-d / 2768720
• FlyBaseID: FBgn0053503
• Length: 521
• Species: Drosophila melanogaster
• Alignment Length: 524
• Identity: 191/524 - (36%)
• Similarity: 304/524 - (58%)
• Gaps: 36/524 - (6%)

  Fly    22 RNSSVGGTLSQQTQLELADSRIDEKWQQARSFGEIPGPSLLRMLSFFMPGGALRNTNLIQMNRLM 86
            |:|.....|:.    |.|.|.|.|   :.:::.|||.|:..:.:..|||||..:|.::.:....|
  Fly    18 RSSRSASVLAH----EQAKSSITE---EHKTYDEIPRPNKFKFMRAFMPGGEFQNASITEYTSAM 75

  Fly    87 REMYGDIYCIPGMMGKPNAVFTYNPDDFEMTYRNEGVWPIRIGLESLNYYRKIHRPDVFKGVGGL 151
            |:.|||||.:|||.|:.:.|.|:|..|.||.:||||:||.|.||:|:.|:|:..||||:..|.||
  Fly    76 RKRYGDIYVMPGMFGRKDWVTTFNTKDIEMVFRNEGIWPRRDGLDSIVYFREHVRPDVYGEVQGL 140

  Fly   152 ASDQGQEWADIRNKVNPVLMKVQNVRQNLPQLDQISKEFIDKLETQRNPETHTLTTDFHNQLKMW 216
            .:.|.:.|..:|:.:||:.|:.:.:|.....|..|:.|||::::..|:|:|..:..||.:::...
  Fly   141 VASQNEAWGKLRSAINPIFMQPRGLRMYYEPLSNINNEFIERIKEIRDPKTLEVPEDFTDEISRL 205

  Fly   217 AFESISFVALNTRMGLLSDNPDPNADRLA--KHMRDFFNYSFQFDVQPSIWTFYKTAGFKKFLKT 279
            .|||:..||.:.:|||:..|.| |:|.|.  :..||.|..:|:.|:|||:|....|..::|..:|
  Fly   206 VFESLGLVAFDRQMGLIRKNRD-NSDALTLFQTSRDIFRLTFKLDIQPSMWKIISTPTYRKMKRT 269

  Fly   280 YDNITDITSNYIETAMRGFGKNDDGKTK-----------CVLEQLLEHNKKVAVTMVMDMLMAGI 333
            .::..:::...::       :|.|...|           .:||:|:|.:.||||.|.:|:|.||:
  Fly   270 LNDSLNVSQKMLK-------ENQDALEKRRQAGEKINSNSMLERLMEIDPKVAVIMSLDILFAGV 327

  Fly   334 DTTSSACLTILYHLARNPSKQEKLRRELLRILPTTKDSLTDQNTKNMPYLRACIKEGLRITSITP 398
            |.|::....:|..|:::|.||.|||.|||.|:||....|.::|.|:||||||.|||.||......
  Fly   328 DATATLLSAVLLCLSKHPDKQAKLREELLSIMPTKDSLLNEENMKDMPYLRAVIKETLRYYPNGF 392

  Fly   399 GNFRITPKDLVLSGYQVPRGTGVLMGVLELSNDDKYFAQSSEFIPERWLKS-DLAPDIQACPAAR 462
            |..|....|::||||:||:||.||:|...|..:..|:.:..||:|||||:. :....:|.
  Fly   393 GTMRTCQNDVILSGYRVPKGTTVLLGSNVLMKEATYYPRPDEFLPERWLRDPETGKKMQV----- 452

  Fly   463 TRNPFVYLPFGFGPRTCIGKRIAELEIETLLVRLLRSYKVSWLPETPIEYESTIILSPCGDIRFK 527
              :||.:||||||||.|||||:.:||:||.:.:|:|::.|.:..:....:::..::.|.....||
  Fly   453 --SPFTFLPFGFGPRMCIGKRVVDLEMETTVAKLIRNFHVEFNRDASRPFKTMFLMEPAITFPFK 515

  Fly   528 LEPV 531
            ...:
  Fly   516 FTDI 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12b2	NP_611370.2	p450	59..511	CDD:299894	177/465 (38%)
Cyp12d1-d	NP_995812.1	p450	70..508	CDD:299894	170/452 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445016
Domainoid	1	1.000	217	1.000	Domainoid score	I2609
eggNOG	1	0.900	-	-		E2759_KOG0159
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	217	1.000	Inparanoid score	I2311
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D185685at33208
OrthoFinder	1	1.000	-	-		FOG0000720
OrthoInspector	1	1.000	-	-		mtm6352
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24305
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X156
	10	9.900