Protein Alignment Cyp12b2 and sad

DIOPT Version :10

• Sequence 1: NP_611370.2
• Gene: Cyp12b2 / 37163
• FlyBaseID: FBgn0034387
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: XP_310837.6
• Gene: sad / 1271975
• VectorBaseID: AGAMI1_008403
• Length: 501
• Species: Anopheles gambiae
• Alignment Length: 567
• Identity: 139/567 - (24%)
• Similarity: 227/567 - (40%)
• Gaps: 155/567 - (27%)

  Fly    21 NRNSSVGGTLSQQTQLELA-DSRIDEKWQQARSFGEIPGP---SLLRMLSFFMPGGALRNTNLIQ 81
            :|....||   ||.:..:| |||      .|:.|.|:|||   .||.||:..|..|.....:|
Mosquito    10 SRFRCTGG---QQQRAGVAGDSR------GAKPFAEMPGPRRIPLLGMLNDVMQLGKPAELHL-- 63

  Fly    82 MNRLMR--EMYGDIYCIPGMMGKPNAVFTYNPDDFEMTYRNEGVWPIRIGLESLNYYRKIHRPDV 144
              |:.:  |.|||:..:  .:|..||||..:|.....|::.||.:|.....||..|:.|.|  |.
Mosquito    64 --RISKYHEQYGDLVRL--QIGTQNAVFVRDPSLMRKTFQLEGAYPRHPLPESWTYFNKKH--DY 122

  Fly   145 FKGVGGLASDQGQEWADIRNKVNPVLMKVQNVRQNLPQLDQISKEFIDKLETQRNPETHTLTTDF 209
            .:   ||....|:||...|...|..::|                                   ||
Mosquito   123 QR---GLFFMDGKEWLQSRQIFNKPMLK-----------------------------------DF 149

  Fly   210 HNQLKMW------------------------AFESISF--------VALNTRMGLLSDNPDPNAD 242
            |     |                        |||.|..        |.|:..:|........:|:
Mosquito   150 H-----WMEEPIRGTCEATVGHMQQTCDSAAAFEGIEAFLYQWSVEVVLSVMLGSAFTECQQSAE 209

  Fly   243 --RLAKH----MRDFFNYSFQ-FDVQPSIWTFYKTAGFKKFLKTYDNITDITSNYIETAMRGFG- 299
              ||.:.    :.|.|..|.: .::.|:|........:::|.|.......:.:..||     ||
Mosquito   210 FRRLVQQFSAVVYDIFRCSSELMNIPPAIADRLNVQPWQQFEKVVPETIRLATAIIE-----FGI 269

  Fly   300 ---KNDDGKTKCVLEQLLEHNKKVAVTMVMDMLMAGIDTTSSACLTILYHLARNPSKQEKLRREL 361
               :..||....::::|   :|.:.:.:.:|.::|..|||:.|.:..||.||.|.:.|:.:|:::
Mosquito   270 ANAQTRDGLLDLMMQKL---DKPLMMRIFIDFIIAAGDTTAFATVWALYLLASNANLQQSVRQDV 331

  Fly   362 LRILPTTKDSLTDQNTKNMPYLRACIKEGLRITSITPGNFRITPKDLVLSGYQVPRGTGVLMGVL 426
            |           |.||.....::..::|.||:..|.|...|....:.|...|.:|:.|.||:.:.
Mosquito   332 L-----------DSNTLECGAVKGVVRETLRLYPIAPFIGRFVEHESVFGAYALPKDTLVLLSLY 385

  Fly   427 ELSNDDKYFAQSSEFIPERWLKSDLAPDIQACPAARTRNPFVYLPFGFGPRTCIGKRIAELEIET 491
            ....|:::||:...|.|.||.:::      |..::..|.|...|||..|.|:|||::||:|::..
Mosquito   386 SAGRDERFFAEPEAFNPYRWQRTN------AAESSTGRTPSASLPFAIGARSCIGQKIAQLQMHY 444

  Fly   492 LLVRLLRSY-----------------KVSWLPETPIEYESTIILSPC 521
            ||..:|..:                 |:..:|..|::    :.|.||
Mosquito   445 LLSMILTKFDLTLAEADQQDAIKPILKMITVPSAPVK----LCLKPC 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12b2	NP_611370.2	CYP24A1-like	87..525	CDD:410677	116/497 (23%)
sad	XP_310837.6	None