Protein Alignment Cyp12b2 and cyp24a1

DIOPT Version :9

• Sequence 1: NP_611370.2
• Gene: Cyp12b2 / 37163
• FlyBaseID: FBgn0034387
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_001082927.1
• Gene: cyp24a1 / 100004700
• ZFINID: ZDB-GENE-060825-1
• Length: 505
• Species: Danio rerio
• Alignment Length: 499
• Identity: 138/499 - (27%)
• Similarity: 244/499 - (48%)
• Gaps: 78/499 - (15%)

  Fly    50 ARSFGEIPGP-------SLLRMLSFFMPGGALR-NTNLIQMNRLMREMYGDIYCIPGMMGKPNAV 106
            |.|...||||       ||:.::   ..||..| :..||..::    .:|.|:.:  .:|...:|
Zfish    46 AHSLDSIPGPTNWPLFGSLIEVI---RNGGLKRQHETLIHFHK----KFGKIFRM--KLGSFESV 101

  Fly   107 FTYNPDDFEMTYRNEGVWPIRIGLESLNYYRKIHRPDVFKGVGGLASDQGQEWADIRNKVNPVLM 171
            ...:|...|..||.||.:|.|:.::....||.: |.:.:    ||...:|::|..:|:.....||
Zfish   102 HIGSPCLLEALYRKEGSYPERLEIKPWKAYRDM-RDEAY----GLLILEGRDWQRVRSAFQQKLM 161

  Fly   172 KVQNVRQNLPQLDQISKEFIDKLETQRNPETHTLTTDFHNQLKMWAFESISFVALNTRMGLLSDN 236
            |...|.:...::::::.:.|.:: .:.|.:...|    :.:|..|:||:|.:|..:.|.|||.|:
Zfish   162 KPTEVMKLDGKINEVAADLIKRI-GKVNGKMDAL----YFELNKWSFETICYVIYDKRFGLLQDS 221

  Fly   237 PDPNADRLAKHMRDFFNYSFQFDVQPSIWTF----------YKTAG---FKKFLKTYDNITDITS 288
                   ::|...||..     .|:..:.||          :||..   :|...:.:|.|.....
Zfish   222 -------VSKEGMDFIT-----AVKTMMSTFGTMMVTPVELHKTLNTKTWKDHTEAWDRIFSTAK 274

  Fly   289 NYIETAMRGFGKNDDGKTKCVLEQLLEHN----KKVAVTMVMDMLMAGIDTTSSACLTILYHLAR 349
            :||:   :...|..:|:....|..:. ||    ||.......::.:.|::||:::.|.::::|:|
Zfish   275 HYID---KNLQKQSNGEADDFLSDIF-HNGNLTKKELYAATTELQVGGVETTANSMLWVIFNLSR 335

  Fly   350 NPSKQEKLRRELLRILPTTKDSLTDQNTKNMPYLRACIKEGLRITSITPGNFRITPKDLVLSGYQ 414
            ||..|.||.:|:..::|..:.... ::.|:||||:||:||.:|::...|...|...||.||..|.
Zfish   336 NPCAQGKLLKEIQDVVPAGQTPRA-EHIKSMPYLKACLKESMRVSPSVPFTSRTLDKDTVLGDYT 399

  Fly   415 VPRGTGVLMGVLELSNDDKYFAQSSEFIPERWL--KSDLAPDIQACPAARTRNPFVYLPFGFGPR 477
            :|:||.:::....:...::||....:|.|||||  ||.:             |||.::|||.|.|
Zfish   400 LPKGTVLMLNSQAIGVSEEYFDNGRQFRPERWLEEKSSI-------------NPFAHVPFGVGKR 451

  Fly   478 TCIGKRIAELEIETLLVRLLRSYKVSWLPETPIE--YESTIILS 519
            .|||:|:|||:|:..|..:||.||:......|::  :..|::.|
Zfish   452 MCIGRRLAELQIQLGLCWILRDYKIVATDLEPVDSLHSGTLVPS 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12b2	NP_611370.2	p450	59..511	CDD:299894	131/478 (27%)
cyp24a1	NP_001082927.1	p450	53..493	CDD:278495	134/488 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	217	1.000	Domainoid score	I2609
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H68094
Inparanoid	1	1.050	219	1.000	Inparanoid score	I3547
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D185685at33208
OrthoFinder	1	1.000	-	-		FOG0000720
OrthoInspector	1	1.000	-	-		mtm6352
orthoMCL	1	0.900	-	-		OOG6_100895
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X156
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.870