Protein Alignment Cyp12b2 and cyp24a1

DIOPT Version :10

• Sequence 1: NP_611370.2
• Gene: Cyp12b2 / 37163
• FlyBaseID: FBgn0034387
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_001082927.1
• Gene: cyp24a1 / 100004700
• ZFINID: ZDB-GENE-060825-1
• Length: 505
• Species: Danio rerio
• Alignment Length: 499
• Identity: 138/499 - (27%)
• Similarity: 244/499 - (48%)
• Gaps: 78/499 - (15%)

  Fly    50 ARSFGEIPGP-------SLLRMLSFFMPGGALR-NTNLIQMNRLMREMYGDIYCIPGMMGKPNAV 106
            |.|...||||       ||:.::   ..||..| :..||..::    .:|.|:.:  .:|...:|
Zfish    46 AHSLDSIPGPTNWPLFGSLIEVI---RNGGLKRQHETLIHFHK----KFGKIFRM--KLGSFESV 101

  Fly   107 FTYNPDDFEMTYRNEGVWPIRIGLESLNYYRKIHRPDVFKGVGGLASDQGQEWADIRNKVNPVLM 171
            ...:|...|..||.||.:|.|:.::....||.: |.:.:    ||...:|::|..:|:.....||
Zfish   102 HIGSPCLLEALYRKEGSYPERLEIKPWKAYRDM-RDEAY----GLLILEGRDWQRVRSAFQQKLM 161

  Fly   172 KVQNVRQNLPQLDQISKEFIDKLETQRNPETHTLTTDFHNQLKMWAFESISFVALNTRMGLLSDN 236
            |...|.:...::::::.:.|.:: .:.|.:...|    :.:|..|:||:|.:|..:.|.|||.|:
Zfish   162 KPTEVMKLDGKINEVAADLIKRI-GKVNGKMDAL----YFELNKWSFETICYVIYDKRFGLLQDS 221

  Fly   237 PDPNADRLAKHMRDFFNYSFQFDVQPSIWTF----------YKTAG---FKKFLKTYDNITDITS 288
                   ::|...||..     .|:..:.||          :||..   :|...:.:|.|.....
Zfish   222 -------VSKEGMDFIT-----AVKTMMSTFGTMMVTPVELHKTLNTKTWKDHTEAWDRIFSTAK 274

  Fly   289 NYIETAMRGFGKNDDGKTKCVLEQLLEHN----KKVAVTMVMDMLMAGIDTTSSACLTILYHLAR 349
            :||:   :...|..:|:....|..:. ||    ||.......::.:.|::||:::.|.::::|:|
Zfish   275 HYID---KNLQKQSNGEADDFLSDIF-HNGNLTKKELYAATTELQVGGVETTANSMLWVIFNLSR 335

  Fly   350 NPSKQEKLRRELLRILPTTKDSLTDQNTKNMPYLRACIKEGLRITSITPGNFRITPKDLVLSGYQ 414
            ||..|.||.:|:..::|..:.... ::.|:||||:||:||.:|::...|...|...||.||..|.
Zfish   336 NPCAQGKLLKEIQDVVPAGQTPRA-EHIKSMPYLKACLKESMRVSPSVPFTSRTLDKDTVLGDYT 399

  Fly   415 VPRGTGVLMGVLELSNDDKYFAQSSEFIPERWL--KSDLAPDIQACPAARTRNPFVYLPFGFGPR 477
            :|:||.:::....:...::||....:|.|||||  ||.:             |||.::|||.|.|
Zfish   400 LPKGTVLMLNSQAIGVSEEYFDNGRQFRPERWLEEKSSI-------------NPFAHVPFGVGKR 451

  Fly   478 TCIGKRIAELEIETLLVRLLRSYKVSWLPETPIE--YESTIILS 519
            .|||:|:|||:|:..|..:||.||:......|::  :..|::.|
Zfish   452 MCIGRRLAELQIQLGLCWILRDYKIVATDLEPVDSLHSGTLVPS 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12b2	NP_611370.2	CYP24A1-like	87..525	CDD:410677	125/454 (28%)
cyp24a1	NP_001082927.1	CYP24A1	84..499	CDD:410738	125/458 (27%)