Protein Alignment Hs3st-A and HS3ST2

DIOPT Version :9

• Sequence 1: NP_001286589.1
• Gene: Hs3st-A / 37161
• FlyBaseID: FBgn0053147
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: NP_006034.1
• Gene: HS3ST2 / 9956
• HGNCID: 5195
• Length: 367
• Species: Homo sapiens
• Alignment Length: 489
• Identity: 153/489 - (31%)
• Similarity: 210/489 - (42%)
• Gaps: 149/489 - (30%)

  Fly   131 GVSRPKLAVVFLTVMLISLFLTFHVLYDSAVYNIQAAQAVHERHRL--------SMTASASALAS 187
            |..:|:.|...|....:||..|:      ..|:.........|.||        ..:|....|..
Human    10 GPPQPRRARRLLFAFTLSLSCTY------LCYSFLCCCDDLGRSRLLGAPRCLRGPSAGGQKLLQ 68

  Fly   188 SSSSSSNSGSSFSSAGGASNHLPVFVKPVP---SSNQLSHPMVFPSSRVHFPKTSRRLPQALIIG 249
            .|.....||.:.|.....|  .|....|.|   .||....|.:          .::|||||||:|
Human    69 KSRPCDPSGPTPSEPSAPS--APAAAVPAPRLSGSNHSGSPKL----------GTKRLPQALIVG 121

  Fly   250 VRKCGTRALLEMLYLHPRIQKAGGEVHFFDRDENYLKGLEWYRKKMPHSFRGQITIEKSPSYFVS 314
            |:|.||||:||.:.:||.::..|.|.|||||  ||.:||:|||..||.:...|||:||:|||||:
Human   122 VKKGGTRAVLEFIRVHPDVRALGTEPHFFDR--NYGRGLDWYRSLMPRTLESQITLEKTPSYFVT 184

  Fly   315 PEVPERVRAMNASIKLLLIVREPVTRAISDYTQLRSHAATAILPLAEKDPPSPRESSGGGAGGGG 379
            .|.|.|:..|:...||:::||.|||||||||||..|           |.|..|
Human   185 QEAPRRIFNMSRDTKLIVVVRNPVTRAISDYTQTLS-----------KKPDIP------------ 226

  Fly   380 AGGGGGSGTAAAKMPTQSLLYAKLQSARGYDNALLGGSGAGAKETKGKTVSSSLVRRQALGSGGG 444
                                                                             
Human   227 ----------------------------------------------------------------- 226

  Fly   445 VAGAAMTTTTMSPMASAAQMAAKSFEELAIFPN---GTVNEAYRPLSISMYHVHLHRWLEVFPRE 506
                                   :||.|: |.|   |.|:.::..:.|.||.:||..||:.||..
Human   227 -----------------------TFEGLS-FRNRTLGLVDVSWNAIRIGMYVLHLESWLQYFPLA 267

  Fly   507 QLLVVNGDRLIEDPVSQLKRIEAFLGIEHRVNSEHFYFNETKGFYCLRYDNGD---RCLRETKGR 568
            |:..|:|:|||.||..::.|::.||||:..:..:|||||:||||.||:.....   |||.::|||
Human   268 QIHFVSGERLITDPAGEMGRVQDFLGIKRFITDKHFYFNKTKGFPCLKKTESSLLPRCLGKSKGR 332

  Fly   569 KHPHVDPVVVSRLRKFFAEYNQRFYELVGEDLGW 602
            .|..:||.|:.:||:|:..||.:|||.||:|..|
Human   333 THVQIDPEVIDQLREFYRPYNIKFYETVGQDFRW 366

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hs3st-A	NP_001286589.1	Sulfotransfer_1	242..587	CDD:304426	119/350 (34%)
HS3ST2	NP_006034.1	cytoplasmic domain	1..19		3/8 (38%)
		transmembrane domain	20..41		5/26 (19%)
		sulfotransferase domain	110..367		129/371 (35%)
		Sulfotransfer_1	114..351	CDD:395556	119/350 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D712400at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820