Protein Alignment Hs3st-A and HS3ST3B1

DIOPT Version :10

• Sequence 1: NP_788409.1
• Gene: Hs3st-A / 37161
• FlyBaseID: FBgn0053147
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: NP_006032.1
• Gene: HS3ST3B1 / 9953
• HGNCID: 5198
• Length: 390
• Species: Homo sapiens
• Alignment Length: 487
• Identity: 158/487 - (32%)
• Similarity: 220/487 - (45%)
• Gaps: 145/487 - (29%)

  Fly   134 RPKLAVVFLTVMLISLFLTFHVLYDSAVYNIQA---------AQAVHERHRLSMTASAS--ALAS 187
            |.|||::| .::.:.|::   .||..|.....|         ::|.|:...|:.....:  .|..
Human    30 RRKLALLF-AMLCVWLYM---FLYSCAGSCAAAPGLLLLGSGSRAAHDPPALATAPDGTPPRLPF 90

  Fly   188 SSSSSSNSGSSFSSAGGASNHLPVFVKP-VPSSNQLSHPMVFPSSRVHFPKTSRRLPQALIIGVR 251
            .:..::...|....|.||::  |....| ||.|..       |.|.......|::||||:||||:
Human    91 RAPPATPLASGKEMAEGAAS--PEEQSPEVPDSPS-------PISSFFSGSGSKQLPQAIIIGVK 146

  Fly   252 KCGTRALLEMLYLHPRIQKAGGEVHFFDRDENYLKGLEWYRKKMPHSFRGQITIEKSPSYFVSPE 316
            |.|||||||.|.:||.::..|.|.|||||  :|.|||.|||..||.:..||||:||:|||||:.|
Human   147 KGGTRALLEFLRVHPDVRAVGAEPHFFDR--SYDKGLAWYRDLMPRTLDGQITMEKTPSYFVTRE 209

  Fly   317 VPERVRAMNASIKLLLIVREPVTRAISDYTQLRSHAATAILPLAEKDPPSPRESSGGGAGGGGAG 381
            .|.|:.||:...||:::||:|||||||||||..|           |.|..|
Human   210 APARISAMSKDTKLIVVVRDPVTRAISDYTQTLS-----------KRPDIP-------------- 249

  Fly   382 GGGGSGTAAAKMPTQSLLYAKLQSARGYDNALLGGSGAGAKETKGKTVSSSLVRRQALGSGGGVA 446
                                                                             
Human   250 ----------------------------------------------------------------- 249

  Fly   447 GAAMTTTTMSPMASAAQMAAKSFEELAIFPN---GTVNEAYRPLSISMYHVHLHRWLEVFPREQL 508
                                 :||.|. |.|   |.::.::..:.|.:|..||..||..||..|:
Human   250 ---------------------TFESLT-FKNRTAGLIDTSWSAIQIGIYAKHLEHWLRHFPIRQM 292

  Fly   509 LVVNGDRLIEDPVSQLKRIEAFLGIEHRVNSEHFYFNETKGFYCLRYDNGD---RCLRETKGRKH 570
            |.|:|:|||.||..:|.|::.|||::..:..:|||||:||||.||:...|.   .||.:||||.|
Human   293 LFVSGERLISDPAGELGRVQDFLGLKRIITDKHFYFNKTKGFPCLKKAEGSSRPHCLGKTKGRTH 357

  Fly   571 PHVDPVVVSRLRKFFAEYNQRFYELVGEDLGW 602
            |.:|..||.|||:|:..:|.:||::.|.|.||
Human   358 PEIDREVVRRLREFYRPFNLKFYQMTGHDFGW 389

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hs3st-A	NP_788409.1	Sulfotransfer_1	242..587	CDD:473908	125/350 (36%)
HS3ST3B1	NP_006032.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..25
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	74..133		13/67 (19%)
		Sulfotransfer_1	137..374	CDD:425820	125/350 (36%)