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Protein Alignment Hs3st-A and HS3ST4

DIOPT Version :9

Sequence 1:	NP_001286589.1	Gene:	Hs3st-A / 37161	FlyBaseID:	FBgn0053147	Length:	605	Species:	Drosophila melanogaster
Sequence 2:	NP_006031.2	Gene:	HS3ST4 / 9951	HGNCID:	5200	Length:	456	Species:	Homo sapiens

Alignment Length:	448	Identity:	146/448 - (32%)
Similarity:	203/448 - (45%)	Gaps:	151/448 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   164 IQAAQAVHERHRLSMTASASALASSSSSSSNSGSSFSSAGGASNHLPVFVKPVPSSNQLSHPMVF 228
            |.|..|:.||.     |..|:......:...:.:..|..|||.:        .|...:
Human   150 ITAQSALPERE-----AQESSTTDEDLAGRRAANGSSERGGAVS--------TPDYGE------- 194

  Fly   229 PSSRVHFPKTSRRLPQALIIGVRKCGTRALLEMLYLHPRIQKAGGEVHFFDRDENYLKGLEWYRK 293
                       ::|||||||||:|.|||||||.:.:||.::..|.|.|||||  ||.|||||||.
Human   195 -----------KKLPQALIIGVKKGGTRALLEAIRVHPDVRAVGVEPHFFDR--NYEKGLEWYRN 246

  Fly   294 KMPHSFRGQITIEKSPSYFVSPEVPERVRAMNASIKLLLIVREPVTRAISDYTQLRSHAATAILP 358
            .||.:..||||:||:|||||:.|.|:|:.:|...|||:::||.|||||||||||..|
Human   247 VMPKTLDGQITMEKTPSYFVTNEAPKRIHSMAKDIKLIVVVRNPVTRAISDYTQTLS-------- 303

  Fly   359 LAEKDPPSPRESSGGGAGGGGAGGGGGSGTAAAKMPTQSLLYAKLQSARGYDNALLGGSGAGAKE 423
               |.|..|
Human   304 ---KKPEIP-------------------------------------------------------- 309

  Fly   424 TKGKTVSSSLVRRQALGSGGGVAGAAMTTTTMSPMASAAQMAAKSFEELAIFPN---GTVNEAYR 485
                                                        :||.|| |.|   |.::.::.
Human   310 --------------------------------------------TFEVLA-FKNRTLGLIDASWS 329

  Fly   486 PLSISMYHVHLHRWLEVFPREQLLVVNGDRLIEDPVSQLKRIEAFLGIEHRVNSEHFYFNETKGF 550
            .:.|.:|.:||..||:.||..|:|.|:|:|||.||..::.:::.|||::..|..:|||||:||||
Human   330 AIRIGIYALHLENWLQYFPLSQILFVSGERLIVDPAGEMAKVQDFLGLKRVVTEKHFYFNKTKGF 394

  Fly   551 YCLRY---DNGDRCLRETKGRKHPHVDPVVVSRLRKFFAEYNQRFYELVGEDLGWPEE 605
            .||:.   .:..|||.::|||.||.:||.|:.|||||:..:|..||::.|:|..|.:|
Human   395 PCLKKPEDSSAPRCLGKSKGRTHPRIDPDVIHRLRKFYKPFNLMFYQMTGQDFQWEQE 452

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.