Protein Alignment Hs3st-A and NDST3

DIOPT Version :10

• Sequence 1: NP_788409.1
• Gene: Hs3st-A / 37161
• FlyBaseID: FBgn0053147
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: XP_016864328.1
• Gene: NDST3 / 9348
• HGNCID: 7682
• Length: 899
• Species: Homo sapiens
• Alignment Length: 654
• Identity: 148/654 - (22%)
• Similarity: 231/654 - (35%)
• Gaps: 244/654 - (37%)

  Fly     7 RASSSNSSGSSNTSGS--SNGNEQHSQQQHLQLQQQQQ--------QHAQPNEY-------QQL- 53
            ||..:|.:.:...||.  ..|.|:..:.....|....:        .|.||:.:       :|:
Human   337 RAQITNFTFNLGFSGKFYHTGTEEEDEGDDCLLGSVDEFWWFPHMWSHMQPHLFHNESSLVEQMI 401

  Fly    54 ------LQH-----------PHH------HYQQHYSGNNNTSGNNSNSSNTQQY-HQRQQQHQAT 94
                  |:|           |||      |.|.:.:.....   |...::|::| |.:..:::..
Human   402 LNKKFALEHGIPTDMGYAVAPHHSGVYPVHVQLYEAWKKVW---NIKITSTEEYPHLKPARYRRG 463

  Fly    95 LRDCSVKLPLDILWLPKSAM-----------RPAGP---DTSPTDCILVVGVSRPKLAVVFLTVM 145
            .      :..:|:.||:...           .|.||   |.|      :.|      ..:|.||:
Human   464 F------IHKNIMVLPRQTCGLFTHTIFYKEYPGGPKELDKS------IQG------GELFFTVV 510

  Fly   146 L--ISLFLTFHVLYDSAVYNIQAAQAVHERHRLSMTASASALASSSSSSSNSGSSFSSAGGASNH 208
            |  ||:|:|....|.:              .||.:....: ||:...|.:|.         ....
Human   511 LNPISIFMTHLSNYGN--------------DRLGLYTFVN-LANFVKSWTNL---------RLQT 551

  Fly   209 LPVFVKPVPSSNQLSHPM--VFPSSRVHF----------------PKTSRRLPQALIIGVRKCGT 255
            ||    ||    ||:|..  :||..:...                .||..|||:.|:||.:|.||
Human   552 LP----PV----QLAHKYFELFPDQKDPLWQNPCDDKRHRDIWSKEKTCDRLPKFLVIGPQKTGT 608

  Fly   256 RALLEMLYLHPRI------QKAGGEVHFFDRDENYLKGLEWYRK--KMPHSFRGQITIEKSPSYF 312
            .||...|.:||.|      .|...||.||:|: ||.:|::||..  .:|.:.......|||.:||
Human   609 TALYLFLVMHPSILSNSPSPKTFEEVQFFNRN-NYHRGIDWYMDFFPVPSNVTTDFLFEKSANYF 672

  Fly   313 VSPEVPERVRAMNASIKLLLIVREPVTRAISDYTQLRSHAATAILPLAEKDPPSPRESSGGGAGG 377
            .|.|.|:|..::....|::.|:.:|..||.|.|...|||          :||
Human   673 HSEEAPKRAASLVPKAKIITILIDPSDRAYSWYQHQRSH----------EDP------------- 714

  Fly   378 GGAGGGGGSGTAAAKMPTQSLLYAKLQSARGYDNALLGGSGAGAKETKGKTVSSSLVRRQALGSG 442
                       ||.|.....::.|                        |....|.|
Human   715 -----------AALKFSFYEVISA------------------------GPRAPSEL--------- 735

  Fly   443 GGVAGAAMTTTTMSPMASAAQMAAKSFEELAIFPNGTVNEAYRPLSISMYHVHLHRWLEVFPREQ 507
                                    ::.::..:.|             ..|..|:.|||..||..|
Human   736 ------------------------RALQKRCLVP-------------GWYASHIERWLVYFPPFQ 763

  Fly   508 LLVVNGDRLIEDPVSQLKRIEAFLGI-EHRVNSEHFYFNETKGFYCLRYDNG-DRCLRETKGRKH 570
            ||:::|.:|..||.:.:..::.|||: .|...||...|:..|||:|...:.| .:||.::||||:
Human   764 LLIIDGQQLRTDPATVMDEVQKFLGVLPHYNYSEALTFDSHKGFWCQLLEEGKTKCLGKSKGRKY 828

  Fly   571 PHVD 574
            |.:|
Human   829 PPMD 832

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hs3st-A	NP_788409.1	Sulfotransfer_1	242..587	CDD:473908	89/343 (26%)
NDST3	XP_016864328.1	HSNSD	76..506	CDD:463450	32/189 (17%)
		Sulfotransfer_1	595..824	CDD:425820	83/333 (25%)