Protein Alignment Hs3st-A and Ndst3

DIOPT Version :9

• Sequence 1: NP_001286589.1
• Gene: Hs3st-A / 37161
• FlyBaseID: FBgn0053147
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: NP_112463.2
• Gene: Ndst3 / 83398
• MGIID: 1932544
• Length: 873
• Species: Mus musculus
• Alignment Length: 629
• Identity: 138/629 - (21%)
• Similarity: 232/629 - (36%)
• Gaps: 211/629 - (33%)

  Fly    26 NEQHSQQQHLQLQQQQQQHAQPNEYQQLLQHPHH------HYQQHYSGNNNTSGNNSNSSNTQQY 84
            ||....:|.:..::...:|..|.:....:. |||      |.|.:.:.....   |...::|::|
Mouse   392 NESSLIEQMILNKKFALEHGIPTDMGYAVS-PHHSGVYPVHVQLYEAWKKVW---NIKITSTEEY 452

  Fly    85 -HQRQQQHQATLRDCSVKLPLDILWLPKSAM-----------RPAGP---DTSPTDCILVVGVSR 134
             |.:..:::...      :..:|:.||:...           .|.||   |.|      :.|
Mouse   453 PHLKPARYRRGF------IHKNIMVLPRQTCGLFTHTIFYKEYPGGPRELDKS------IHG--- 502

  Fly   135 PKLAVVFLTVML--ISLFLTFHVLYDSAVYNIQAAQAVHERHRLSMTASASALASSSSSSSNSGS 197
               ..:|.||:|  ||:|:|....|.:              .||.:....: ||:...:.:|
Mouse   503 ---GELFFTVVLNPISIFMTHLSNYGN--------------DRLGLYTFVN-LANFVQTWTN--- 546

  Fly   198 SFSSAGGASNHLPVFVKPVPSSNQLSHPM--VFPSSRVHF----------------PKTSRRLPQ 244
                         :.::.:|.: ||:|..  :||..:...                .||..|||:
Mouse   547 -------------LRLQTLPPA-QLAHKYFELFPDQKDPLWQNPCDDKRHRDIWSKEKTCDRLPK 597

  Fly   245 ALIIGVRKCGTRALLEMLYLHPRI------QKAGGEVHFFDRDENYLKGLEWYRK--KMPHSFRG 301
            .|:||.:|.||.||...|.:||.|      .|:..||.||:|: ||.:|::||..  .:|.:...
Mouse   598 FLVIGPQKTGTTALCLFLIMHPSILSNSPSPKSFEEVQFFNRN-NYHRGIDWYMDFFPVPSNVTT 661

  Fly   302 QITIEKSPSYFVSPEVPERVRAMNASIKLLLIVREPVTRAISDYTQLRSHAATAILPLAEKDPPS 366
            ....|||.:||.|.:.|:|..::....|::.|:.:|..||.|.|...|||          :||
Mouse   662 DFLFEKSANYFHSEDAPKRAASLVPKAKIITILIDPSDRAYSWYQHQRSH----------EDP-- 714

  Fly   367 PRESSGGGAGGGGAGGGGGSGTAAAKMPTQSLLYAKLQSARGYDNALLGGSGAGAKETKGKTVSS 431
                                  ||.|.....::                  .||..
Mouse   715 ----------------------AALKFSFYEVI------------------SAGPN--------- 730

  Fly   432 SLVRRQALGSGGGVAGAAMTTTTMSPMASAAQMAAKSFEELAIFPNGTVNEAYRPLSISMYHVHL 496
                                          |....::.::..:.|....|             |:
Mouse   731 ------------------------------APWELRTLQKRCLVPGWYAN-------------HI 752

  Fly   497 HRWLEVFPREQLLVVNGDRLIEDPVSQLKRIEAFLGIEHRVN-SEHFYFNETKGFYCLRYDNG-D 559
            .|||..||..|||:::|.:|...|.:.:..::.|||:....| ||...|:..|||:|...:.| .
Mouse   753 ERWLVYFPPFQLLIIDGQQLRTTPATVMDEVQKFLGVSPHYNYSEALTFDSHKGFWCQLLEEGKT 817

  Fly   560 RCLRETKGRKHPHVDPVVVSRLRKFFAEYNQRFYELVGEDLGWP 603
            :||.::||||:|.:|....:.|..::.::|....:|: ..||.|
Mouse   818 KCLGKSKGRKYPPMDSDSRAFLSSYYRDHNVELSKLL-HRLGQP 860

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hs3st-A	NP_001286589.1	Sulfotransfer_1	242..587	CDD:304426	87/354 (25%)
Ndst3	NP_112463.2	HSNSD	21..506	CDD:371875	23/135 (17%)
		Heparan sulfate N-deacetylase 3	36..589		43/250 (17%)
		Heparan sulfate N-sulfotransferase 3	590..873		95/377 (25%)
		Sulfotransfer_1	595..846	CDD:366246	87/355 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810