DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hs3st-A and hs3st1

DIOPT Version :9

Sequence 1:	NP_001286589.1	Gene:	Hs3st-A / 37161	FlyBaseID:	FBgn0053147	Length:	605	Species:	Drosophila melanogaster
Sequence 2:	NP_001074062.1	Gene:	hs3st1 / 565201	ZFINID:	ZDB-GENE-070202-1	Length:	293	Species:	Danio rerio

Alignment Length:	388	Identity:	129/388 - (33%)
Similarity:	192/388 - (49%)	Gaps:	114/388 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   219 SNQLSHPMVFPSSRVHFPK-TSRRLPQALIIGVRKCGTRALLEMLYLHPRIQKAGGEVHFFDRDE 282
            |:.|...::.|......|: .:|.||..:||||||.|||||::||.||..|..|..||||||.|.
Zfish    15 SSVLVSGVISPPDAALTPRANARHLPDIIIIGVRKAGTRALIQMLRLHTSIAAAQNEVHFFDWDS 79

  Fly   283 NYLKGLEWYRKKMPHSFRGQITIEKSPSYFVSPEVPERVRAMNASIKLLLIVREPVTRAISDYTQ 347
            :|.:||:||..:||.:..|::|:||:|:||.|.:||:|:|......:||||||||..|.:|||||
Zfish    80 HYERGLDWYVDQMPEAQPGRLTVEKTPAYFTSRDVPQRIRLAKPDARLLLIVREPTERLLSDYTQ 144

  Fly   348 LRSHAATAILPLAEKDPPSPRESSGGGAGGGGAGGGGGSGTAAAKMPTQSLLYAKLQSARGYDNA 412
            :                                                            |.|.
Zfish   145 V------------------------------------------------------------YHNR 149

  Fly   413 LLGGSGAGAKETKGKTVSSSLVRRQALGSGGGVAGAAMTTTTMSPMASAAQMAAKSFEELAIFPN 477
            |       .|..:.:.:.:.|:|                                         |
Zfish   150 L-------EKRKRPQPLETLLLR-----------------------------------------N 166

  Fly   478 GTVNEAYRPLSISMYHVHLHRWLEVFPREQLLVVNGDRLIEDPVSQLKRIEAFLGIEHRVNSEHF 542
            |.:|..|:||:.|:||.|:.|||:.||.....:|:||.|:.:|:::::::||||.::.:::..:|
Zfish   167 GELNLDYKPLNRSLYHTHMQRWLQAFPISSFHLVDGDALVREPLAEMQKVEAFLKLQPQISQNNF 231

  Fly   543 YFNETKGFYCLRYDNG---DRCLRETKGRKHPHVDPVVVSRLRKFFAEYNQRFYELVGEDLGW 602
            |||:|:||:|||  :|   .|||..:||||||.|.|.::|:|:.||.|.|:||:||||....|
Zfish   232 YFNQTRGFFCLR--DGRQQQRCLHSSKGRKHPQVSPHILSKLQHFFHEPNRRFFELVGRTFDW 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hs3st-A	NP_001286589.1	Sulfotransfer_1	242..587	CDD:304426	115/347 (33%)
hs3st1	NP_001074062.1	Sulfotransfer_1	39..277	CDD:304426	115/347 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D522194at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5230
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.040