Protein Alignment Hs3st-A and Ndst1

DIOPT Version :9

• Sequence 1: NP_001286589.1
• Gene: Hs3st-A / 37161
• FlyBaseID: FBgn0053147
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: NP_077337.1
• Gene: Ndst1 / 29633
• RGDID: 69303
• Length: 882
• Species: Rattus norvegicus
• Alignment Length: 602
• Identity: 131/602 - (21%)
• Similarity: 215/602 - (35%)
• Gaps: 182/602 - (30%)

  Fly    43 QHAQPNEYQQLLQHPHH------HYQQHYSGNNNTSGNNSNSSNTQQY-HQRQQQHQATLRDCSV 100
            :|..|.:....:. |||      |.|.:.:.....   |...::|::| |.:..:::...
  Rat   418 EHGIPTDMGYAVA-PHHSGVYPVHVQLYEAWKQVW---NIRVTSTEEYPHLKPARYRRGF----- 473

  Fly   101 KLPLDILWLPKSAM-----------RPAGPDTSPTDCILVVGVSRPKLAVVFLTVML--ISLFLT 152
             :...|:.||:...           .|.|  :|..|.|:..|       .:||||:|  ||:|:|
  Rat   474 -IHNGIMVLPRQTCGLFTHTIFYNEYPGG--SSELDKIINGG-------ELFLTVLLNPISVFMT 528

  Fly   153 FHVLYDS---AVYNIQ-AAQAVHERHRLSM-TASASALASSSSSSSNSGSSFSSAGGASNHLPVF 212
            ....|.:   .:|..: ..:.:|....|.: |.....||.......:....           |::
  Rat   529 HLSNYGNDRLGLYTFKHLVRFLHSWTNLRLQTLPPVQLAQKYFQIFSEEKD-----------PLW 582

  Fly   213 VKPVPSSNQLSHPMVFPSSRVHFPKTSRRLPQALIIGVRKCGTRALLEMLYLHPRI------QKA 271
            ..|.....   |..::...     ||..|.|:.||||.:|.||.||...|.:||.:      .:.
  Rat   583 QDPCEDKR---HKDIWSKE-----KTCDRFPKLLIIGPQKTGTTALYLFLGMHPDLSSNYPSSET 639

  Fly   272 GGEVHFFDRDENYLKGLEWYRK--KMPHSFRGQITIEKSPSYFVSPEVPERVRAMNASIKLLLIV 334
            ..|:.||: ..||.||::||.:  .:|.:.......|||.:||.|...|.|..|:....|:|.|:
  Rat   640 FEEIQFFN-GHNYHKGIDWYMEFFPIPSNTTSDFYFEKSANYFDSEVAPRRAAALLPKAKVLTIL 703

  Fly   335 REPVTRAISDYTQLRSHAATAILPLAEKDPPSPRESSGGGAGGGGAGGGGGSGTAAAKMPTQSLL 399
            ..|..||.|.|...|:|           |.|                       .|.|.....::
  Rat   704 INPADRAYSWYQHQRAH-----------DDP-----------------------VALKYTFHEVI 734

  Fly   400 YAKLQSARGYDNALLGGSGAGAKETKGKTVSSSLVRRQALGSGGGVAGAAMTTTTMSPMASAAQM 464
                                    |.|...||.|
  Rat   735 ------------------------TAGPDASSKL------------------------------- 744

  Fly   465 AAKSFEELAIFPNGTVNEAYRPLSISMYHVHLHRWLEVFPREQLLVVNGDRLIEDPVSQLKRIEA 529
              ::.:...:.|             ..|..|:.|||..|...|:||::|..|..:|...:..::.
  Rat   745 --RALQNRCLVP-------------GWYATHIERWLSAFHANQILVLDGKLLRTEPAKVMDTVQK 794

  Fly   530 FLGIEHRVN-SEHFYFNETKGFYCLRYDNG-DRCLRETKGRKHPHVDPVVVSRLRKFFAEYNQRF 592
            |||:...|: .:...|:..|||:|...:.| .:||.::||||:|.:|....:.|:.::.::|...
  Rat   795 FLGVTSTVDYHKTLAFDPKKGFWCQLLEGGKTKCLGKSKGRKYPEMDLDSRAFLKDYYRDHNIEL 859

  Fly   593 YEL---VGEDL-GWPEE 605
            .:|   :|:.| .|..|
  Rat   860 SKLLYKMGQTLPTWLRE 876

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hs3st-A	NP_001286589.1	Sulfotransfer_1	242..587	CDD:304426	83/354 (23%)
Ndst1	NP_077337.1	HSNSD	30..515	CDD:288882	20/115 (17%)
		Heparan sulfate N-deacetylase 1	40..598		39/212 (18%)
		Heparan sulfate N-sulfotransferase 1	599..882		92/383 (24%)
		Sulfotransfer_1	605..855	CDD:279075	83/354 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810