DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hs3st-A and Hs3st5

DIOPT Version :9

Sequence 1:	NP_001286589.1	Gene:	Hs3st-A / 37161	FlyBaseID:	FBgn0053147	Length:	605	Species:	Drosophila melanogaster
Sequence 2:	NP_001099862.1	Gene:	Hs3st5 / 294449	RGDID:	1306379	Length:	346	Species:	Rattus norvegicus

Alignment Length:	409	Identity:	162/409 - (39%)
Similarity:	211/409 - (51%)	Gaps:	112/409 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   200 SSAGGASNHLPVFVKPVPSSNQLSHPMVFPSS---RVHFPKTSRRLPQALIIGVRKCGTRALLEM 261
            |..|.|.|...:.::.:.....|.|.....:|   :|......::||:|:||||||.||||||||
  Rat    45 SRFGAAHNQAELPLRALQFKRGLLHEFRKGNSSKEQVRLHDLVQQLPKAIIIGVRKGGTRALLEM 109

  Fly   262 LYLHPRIQKAGGEVHFFDRDENYLKGLEWYRKKMPHSFRGQITIEKSPSYFVSPEVPERVRAMNA 326
            |.|||.:.||..|:||||.||||.||:||||||||.|:..||||||||:||::.|||||:..||:
  Rat   110 LNLHPAVVKASQEIHFFDNDENYAKGIEWYRKKMPFSYPQQITIEKSPAYFITEEVPERIYKMNS 174

  Fly   327 SIKLLLIVREPVTRAISDYTQLRSHAATAILPLAEKDPPSPRESSGGGAGGGGAGGGGGSGTAAA 391
            |||||:|||||.|||||||||
  Rat   175 SIKLLMIVREPTTRAISDYTQ-------------------------------------------- 195

  Fly   392 KMPTQSLLYAKLQSARGYDNALLGGSGAGAKETKGKTVSSSLVRRQALGSGGGVAGAAMTTTTMS 456
                                 :|.|     ||.|.||.
  Rat   196 ---------------------VLEG-----KERKNKTY--------------------------- 207

  Fly   457 PMASAAQMAAKSFEELAIFPNG-TVNEAYRPLSISMYHVHLHRWLEVFPREQLLVVNGDRLIEDP 520
                      ..||:|||.||. .||..|:.:..|:|..||.|||:.||.||..:|:|||||.:|
  Rat   208 ----------YKFEKLAIDPNTCEVNTKYKAVRTSIYTKHLERWLKYFPIEQFHIVDGDRLITEP 262

  Fly   521 VSQLKRIEAFLGIEHRVNSEHFYFNETKGFYCLRYD-NGDRCLRETKGRKHPHVDPVVVSRLRKF 584
            :.:|:.:|.||.:..|::..:.|||.|:||||||:: ..::||..:|||.||.|||.||::||||
  Rat   263 LPELQLVEKFLNLPPRISQYNLYFNATRGFYCLRFNIIFNKCLAGSKGRIHPEVDPSVVTKLRKF 327

  Fly   585 FAEYNQRFYELVGEDLGWP 603
            |..:||:||::.|..|.||
  Rat   328 FHPFNQKFYQITGRTLNWP 346

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hs3st-A	NP_001286589.1	Sulfotransfer_1	242..587	CDD:304426	146/346 (42%)
Hs3st5	NP_001099862.1	Sulfotransfer_1	90..330	CDD:279075	146/346 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166341444
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3704
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H17796
Inparanoid	1	1.050	310	1.000	Inparanoid score	I2525
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D522194at33208
OrthoFinder	1	1.000	-	-		FOG0009926
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_109628
Panther	1	1.100	-	-	O	PTHR10605
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2317
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.760