Protein Alignment Hs3st-A and Ndst1

DIOPT Version :9

• Sequence 1: NP_001286589.1
• Gene: Hs3st-A / 37161
• FlyBaseID: FBgn0053147
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: NP_001335029.1
• Gene: Ndst1 / 15531
• MGIID: 104719
• Length: 882
• Species: Mus musculus
• Alignment Length: 601
• Identity: 134/601 - (22%)
• Similarity: 213/601 - (35%)
• Gaps: 180/601 - (29%)

  Fly    43 QHAQPNEYQQLLQHPHHH--YQQH---YSGNNNTSGNNSNSSNTQQY-HQRQQQHQATLRDCSVK 101
            :|..|.:....:. |||.  |..|   |.......|....|  |::| |.:..:::...
Mouse   418 EHGIPTDMGYAVA-PHHSGVYPVHVQLYEAWKQVWGIRVTS--TEEYPHLKPARYRRGF------ 473

  Fly   102 LPLDILWLPKSAM-----------RPAGPDTSPTDCILVVGVSRPKLAVVFLTVML--ISLFLTF 153
            :...|:.||:...           .|.|  :|..|.|:..|       .:||||:|  ||:|:|.
Mouse   474 IHNGIMVLPRQTCGLFTHTIFYNEYPGG--SSELDKIINGG-------ELFLTVLLNPISIFMTH 529

  Fly   154 HVLYDS---AVYNIQ-AAQAVHERHRLSM-TASASALASSSSSSSNSGSSFSSAGGASNHLPVFV 213
            ...|.:   .:|..: ..:.:|....|.: |.....||.......:....           |::.
Mouse   530 LSNYGNDRLGLYTFKHLVRFLHSWTNLRLQTLPPVQLAQKYFQIFSEEKD-----------PLWQ 583

  Fly   214 KPVPSSNQLSHPMVFPSSRVHFPKTSRRLPQALIIGVRKCGTRALLEMLYLHPRI------QKAG 272
            .|.....   |..::...     ||..|.|:.||||.:|.||.||...|.:||.:      .:..
Mouse   584 DPCEDKR---HKDIWSKE-----KTCDRFPKLLIIGPQKTGTTALYLFLGMHPDLSSNYPSSETF 640

  Fly   273 GEVHFFDRDENYLKGLEWYRK--KMPHSFRGQITIEKSPSYFVSPEVPERVRAMNASIKLLLIVR 335
            .|:.||: ..||.||::||.:  .:|.:.......|||.:||.|...|.|..|:....|:|.|:.
Mouse   641 EEIQFFN-GHNYHKGIDWYMEFFPIPSNTTSDFYFEKSANYFDSEVAPRRAAALLPKAKILSILI 704

  Fly   336 EPVTRAISDYTQLRSHAATAILPLAEKDPPSPRESSGGGAGGGGAGGGGGSGTAAAKMPTQSLLY 400
            .|..||.|.|...|:|           |.|                       .|.|.....::
Mouse   705 NPADRAYSWYQHQRAH-----------DDP-----------------------VALKYTFHEVI- 734

  Fly   401 AKLQSARGYDNALLGGSGAGAKETKGKTVSSSLVRRQALGSGGGVAGAAMTTTTMSPMASAAQMA 465
                                   |.|...||.|
Mouse   735 -----------------------TAGPDASSKL-------------------------------- 744

  Fly   466 AKSFEELAIFPNGTVNEAYRPLSISMYHVHLHRWLEVFPREQLLVVNGDRLIEDPVSQLKRIEAF 530
             ::.:...:.|             ..|..|:.|||..|...|:||::|..|..:|...:..::.|
Mouse   745 -RALQNRCLVP-------------GWYATHIERWLSAFHANQILVLDGKLLRTEPAKVMDTVQKF 795

  Fly   531 LGIEHRVN-SEHFYFNETKGFYCLRYDNG-DRCLRETKGRKHPHVDPVVVSRLRKFFAEYNQRFY 593
            ||:...|: .:...|:..|||:|...:.| .:||.::||||:|.:|....:.|:.:|.::|....
Mouse   796 LGVTSTVDYHKTLAFDPKKGFWCQLLEGGKTKCLGKSKGRKYPEMDLDSRAFLKDYFRDHNIELS 860

  Fly   594 EL---VGEDL-GWPEE 605
            :|   :|:.| .|..|
Mouse   861 KLLYKMGQTLPTWLRE 876

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hs3st-A	NP_001286589.1	Sulfotransfer_1	242..587	CDD:304426	84/354 (24%)
Ndst1	NP_001335029.1	HSNSD	30..515	CDD:403326	22/114 (19%)
		Heparan sulfate N-deacetylase 1	40..598		41/211 (19%)
		Heparan sulfate N-sulfotransferase 1	599..882		93/383 (24%)
		Sulfotransfer_1	605..855	CDD:395556	84/354 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810