DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17821 and Elovl4

DIOPT Version :9

Sequence 1:	NP_725820.2	Gene:	CG17821 / 37159	FlyBaseID:	FBgn0034383	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	NP_683743.2	Gene:	Elovl4 / 83603	MGIID:	1933331	Length:	312	Species:	Mus musculus

Alignment Length:	256	Identity:	90/256 - (35%)
Similarity:	146/256 - (57%)	Gaps:	33/256 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 PMFGTPLPAIVIVLGYLLLIFKVGPDFMRSRKPYNMRKAMLIYNFCQVLMNSGIF---LMGTY-- 79
            |:..:|.|.|.|...|||.:: :||.:|:.|:|:.||..::||||..||:|..||   .||:|
Mouse    41 PLMQSPWPTISISTLYLLFVW-LGPKWMKDREPFQMRLVLIIYNFGMVLLNLFIFRELFMGSYNA 104

  Fly    80 -YLFIKKLYDFRCMTMLSSDHPDKDVDRL----LTYFYFINKVIDLIDTIFFVLRKSNKQITVLH 139
             |.:|.:..|:           ..||:.:    ..::||::|.::.:||:||:|||.|.|::.||
Mouse   105 GYSYICQSVDY-----------SNDVNEVRIAGALWWYFVSKGVEYLDTVFFILRKKNNQVSFLH 158

  Fly   140 VYHHVFMVLGVPLTYYFYG----PGGQYNLMGYLNSFVHVVMYAYYFASAWYPNVKSTFWWKEYI 200
            ||||..|     .|.::.|    .|||......:|||:||:||:||..:|:.|.::...|||.|:
Mouse   159 VYHHCTM-----FTLWWIGIKWVAGGQAFFGAQMNSFIHVIMYSYYGLTAFGPWIQKYLWWKRYL 218

  Fly   201 TKLQFLQFMILFAQSVLTLWLNPGCRFPKVLQYVQLGGSVSMMTMFGNFYYQTYVKAKSKE 261
            |.||.:||.:....:.|:|:.:  |.|||.:.:..:..::|.:.:|.|||.:||.:.|..:
Mouse   219 TMLQLVQFHVTIGHTALSLYTD--CPFPKWMHWALIAYAISFIFLFLNFYTRTYNEPKQSK 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17821	NP_725820.2	ELO	20..262	CDD:279492	90/256 (35%)
Elovl4	NP_683743.2	ELO	41..277	CDD:279492	90/254 (35%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	273..312		1/5 (20%)
		Di-lysine motif. /evidence=ECO:0000255\|HAMAP-Rule:MF_03204, ECO:0000269\|PubMed:24569140	308..312
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3071
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1094172at2759
OrthoFinder	1	1.000	-	-		FOG0000078
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X54
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.820