DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17821 and ELOVL7

DIOPT Version :9

Sequence 1:	NP_725820.2	Gene:	CG17821 / 37159	FlyBaseID:	FBgn0034383	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	NP_001098028.1	Gene:	ELOVL7 / 79993	HGNCID:	26292	Length:	281	Species:	Homo sapiens

Alignment Length:	274	Identity:	94/274 - (34%)
Similarity:	140/274 - (51%)	Gaps:	35/274 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 FRGLPADPVHL---------P------MFGTPLPAIVIVLGYLLLIFKVGPDFMRSRKPYNMRKA 58
            |..|.:..|||         |      :..:|||..:::..|:..:..:||..|.:|||:.::||
Human     3 FSDLTSRTVHLYDNWIKDADPRVEDWLLMSSPLPQTILLGFYVYFVTSLGPKLMENRKPFELKKA 67

  Fly    59 MLIYNFCQVLMNSGIFLMGTYYLFIKK----LYDFRCMTMLSSDHPDKDVDRLLTYFYFINKVID 119
            |:.|||..||     |.:...|.|:..    .|.|||..:..|..|.........:.|:.:|.|:
Human    68 MITYNFFIVL-----FSVYMCYEFVMSGWGIGYSFRCDIVDYSRSPTALRMARTCWLYYFSKFIE 127

  Fly   120 LIDTIFFVLRKSNKQITVLHVYHHVFMVLGVPLTYYF---YGPGGQYNLMGYLNSFVHVVMYAYY 181
            |:|||||||||.|.|:|.|||:||..|    |.|::|   :..||.......||:.||||||:||
Human   128 LLDTIFFVLRKKNSQVTFLHVFHHTIM----PWTWWFGVKFAAGGLGTFHALLNTAVHVVMYSYY 188

  Fly   182 FASAWYPNVKSTFWWKEYITKLQFLQFMILFAQSVLTLWLNPGCR--FPKVLQYVQLGGSVSMMT 244
            ..||..|..:...|||:|:|.||.:||:|: |..:...:....|:  || |...:.:..|...:.
Human   189 GLSALGPAYQKYLWWKKYLTSLQLVQFVIV-AIHISQFFFMEDCKYQFP-VFACIIMSYSFMFLL 251

  Fly   245 MFGNFYYQTYVKAK 258
            :|.:|:|:.|.|.:
Human   252 LFLHFWYRAYTKGQ 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17821	NP_725820.2	ELO	20..262	CDD:279492	89/254 (35%)
ELOVL7	NP_001098028.1	ELO	30..269	CDD:307345	88/247 (36%)
ELOVL7	NP_001098028.1	Di-lysine motif. /evidence=ECO:0000255\|HAMAP-Rule:MF_03207	277..281
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3071
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1094172at2759
OrthoFinder	1	1.000	-	-		FOG0000078
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11157
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X54
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.920