DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17821 and ELOVL4

DIOPT Version :9

Sequence 1:	NP_725820.2	Gene:	CG17821 / 37159	FlyBaseID:	FBgn0034383	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	NP_073563.1	Gene:	ELOVL4 / 6785	HGNCID:	14415	Length:	314	Species:	Homo sapiens

Alignment Length:	246	Identity:	88/246 - (35%)
Similarity:	144/246 - (58%)	Gaps:	19/246 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 PMFGTPLPAIVIVLGYLLLIFKVGPDFMRSRKPYNMRKAMLIYNFCQVLMNSGIF---LMGTYYL 81
            |:..:|.|.:.|...|||.:: :||.:|:.|:|:.||..::||||..||:|..||   .||:|
Human    41 PLMQSPWPTLSISTLYLLFVW-LGPKWMKDREPFQMRLVLIIYNFGMVLLNLFIFRELFMGSY-- 102

  Fly    82 FIKKLYDFRCMTMLSSDHPDKDVDRLLTYFYFINKVIDLIDTIFFVLRKSNKQITVLHVYHHVFM 146
              ...|.:.|.::..|::..:.......::||::|.::.:||:||:|||.|.|::.||||||..|
Human   103 --NAGYSYICQSVDYSNNVHEVRIAAALWWYFVSKGVEYLDTVFFILRKKNNQVSFLHVYHHCTM 165

  Fly   147 VLGVPLTYYFYG----PGGQYNLMGYLNSFVHVVMYAYYFASAWYPNVKSTFWWKEYITKLQFLQ 207
                 .|.::.|    .|||......||||:||:||:||..:|:.|.::...|||.|:|.||.:|
Human   166 -----FTLWWIGIKWVAGGQAFFGAQLNSFIHVIMYSYYGLTAFGPWIQKYLWWKRYLTMLQLIQ 225

  Fly   208 FMILFAQSVLTLWLNPGCRFPKVLQYVQLGGSVSMMTMFGNFYYQTYVKAK 258
            |.:....:.|:|:.:  |.|||.:.:..:..::|.:.:|.|||.:||.:.|
Human   226 FHVTIGHTALSLYTD--CPFPKWMHWALIAYAISFIFLFLNFYIRTYKEPK 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17821	NP_725820.2	ELO	20..262	CDD:279492	88/246 (36%)
ELOVL4	NP_073563.1	ELO	41..278	CDD:279492	88/246 (36%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	275..314		88/246 (36%)
		Di-lysine motif. /evidence=ECO:0000255\|HAMAP-Rule:MF_03204	310..314
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3071
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1094172at2759
OrthoFinder	1	1.000	-	-		FOG0000078
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X54
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.820