DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17821 and Elovl2

DIOPT Version :9

Sequence 1:	NP_725820.2	Gene:	CG17821 / 37159	FlyBaseID:	FBgn0034383	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	NP_062296.1	Gene:	Elovl2 / 54326	MGIID:	1858960	Length:	292	Species:	Mus musculus

Alignment Length:	251	Identity:	82/251 - (32%)
Similarity:	139/251 - (55%)	Gaps:	35/251 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 LPAIVIVLGYLLLIFKVGPDFMRSRKPYNMRKAMLIYNFCQVLMNSGIFLMGTYYLFIKKL---- 86
            ||..::.:.|||.|: :|..:|::|...::|..:.:||....|:::        |:.::.:
Mouse    36 LPTFILTITYLLSIW-LGNKYMKNRPALSLRGILTLYNLAITLLSA--------YMLVELILSSW 91

  Fly    87 ---YDFRCMTMLSSDHPDKDVDRLLTYFYFINKVIDLIDTIFFVLRKSNKQITVLHVYHHVFM-- 146
               |:.:|..:.|:...|..|.::|.::|| :|:::.:|||||||||...|||.||||||..|
Mouse    92 EGGYNLQCQNLDSAGEGDVRVAKVLWWYYF-SKLVEFLDTIFFVLRKKTNQITFLHVYHHASMFN 155

  Fly   147 ----VLG-VPLTYYFYGPGGQYNLMGYLNSFVHVVMYAYYFASAWYPNVKSTFWWKEYITKLQFL 206
                ||. :|....|:||        .||||:|::||:||..|. :|::....|||:|:|:.|.:
Mouse   156 IWWCVLNWIPCGQSFFGP--------TLNSFIHILMYSYYGLSV-FPSMHKYLWWKKYLTQAQLV 211

  Fly   207 QFMILFAQSVLTLWLNPGCRFPKVLQYVQLGGSVSMMTMFGNFYYQTYVKAKSKEQ 262
            ||::....: |:..:.| |.||......|....::::.:|.|||.|||.|...|::
Mouse   212 QFVLTITHT-LSAVVKP-CGFPFGCLIFQSSYMMTLVILFLNFYIQTYRKKPVKKE 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17821	NP_725820.2	ELO	20..262	CDD:279492	82/249 (33%)
Elovl2	NP_062296.1	ELO	30..264	CDD:307345	81/248 (33%)
Elovl2	NP_062296.1	Di-lysine motif. /evidence=ECO:0000255\|HAMAP-Rule:MF_03202	289..292
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3071
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1094172at2759
OrthoFinder	1	1.000	-	-		FOG0000078
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X54
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.820