Protein Alignment List and Slc6a19

DIOPT Version :9

• Sequence 1: NP_611364.2
• Gene: List / 37157
• FlyBaseID: FBgn0034381
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_083154.1
• Gene: Slc6a19 / 74338
• MGIID: 1921588
• Length: 634
• Species: Mus musculus
• Alignment Length: 628
• Identity: 196/628 - (31%)
• Similarity: 320/628 - (50%)
• Gaps: 108/628 - (17%)

  Fly     1 MTQLEISKKSEKPAEKPAEQWGNGLEFLFSCISLSVGLGNIWRFPYIAFQNGGGTFVIPYLIALL 65
            :.:||:.:| |:...:|  :|.|..:::.:|:...|||||:|||||:...:|||.|:||:||.|:
Mouse    18 LDELEVIEK-EEAGSRP--KWDNKAQYMLTCVGFCVGLGNVWRFPYLCQSHGGGAFMIPFLILLV 79

  Fly    66 VIGRPVYYLEISLGQFTGRGVVKAF-DMAPLLKGVALGQVLATAASITYYSSIMALTLRFWLASF 129
            ..|.|:.|||.::||...:|.:..: .:.|.|||:.:..:..:.....||::|:|..:.::..||
Mouse    80 FEGIPLLYLEFAIGQRLRKGSMGVWSSIHPALKGIGIASMFVSFMVGLYYNTIIAWVMWYFFNSF 144

  Fly   130 GSELPWSRCWESWGTDCHDGNAQNSSG------KMSPAQLYFEREILHEVPNIDNGLSLPNWQLV 188
            ...||||.|..:          ||.:|      |.|....::.||.|:...:|.:..|: .|.::
Mouse   145 QEPLPWSECPLN----------QNQTGYVEECAKSSSVDYFWYRETLNISTSISDSGSI-QWWIL 198

  Fly   189 ACLAIAWLVIGGVLIRGIKSSGKAAYFLGVFPYVVLLILLLRAVTLPGAIDGIIYFFKPQWRELL 253
            .||..||.|:...:||||:::|||.|.....|||||.|.|:|.:||.||.:||::.|.|...||.
Mouse   199 LCLTCAWSVLYVCIIRGIETTGKAVYITSTLPYVVLTIFLIRGLTLKGATNGIVFLFTPNITELS 263

  Fly   254 NPLVWYAAVTQVFFSLAICFGTLITYASYNNFNRNVYNDIVIITTMDSCSSIIAGCITFGILGNL 318
            ||..|..|..|||:|.::.||.||:::|||:.:.|...|.||::.::..:|:.|..:.:.|:|..
Mouse   264 NPNTWLDAGAQVFYSFSLAFGGLISFSSYNSVHNNCEMDSVIVSVINGFTSVYAATVVYSIIGFR 328

  Fly   319 ARE-------------------------------------TGNP-----------DIGSVVK--- 332
            |.|                                     ..||           ||.|.:.
Mouse   329 ATERFDDCVNTNILTLINGFDLPEGNVTSENFEAYQQWCNATNPQAYAQLKFQTCDINSFLSEGV 393

  Fly   333 GGAGLAFISYPEAIAKFEYVPQMFAVLFFLMLFVLGIGSTVGMGSCILRVIRDQFGLR-SPPIW- 395
            .|.|||||.:.|||.|....| :::||||:|||.||:.|..|....::..::|   |. :|..|
Mouse   394 EGTGLAFIVFTEAITKMPVSP-LWSVLFFIMLFCLGLSSMFGNMEGVVVPLQD---LNITPKKWP 454

  Fly   396 -KLASGLTVLG-FSVSIVYMTPGGQFILNLVDFYGVSFTALILAIGELVAVAWIYGVNRFCEDIK 458
             :|.:||..|| :.::.::....||:.|:|:|.:..|...||:|..|:.||.::|||:||.:||:
Mouse   455 KELLTGLICLGTYLIAFIFTLNSGQYWLSLLDSFAGSIPLLIIAFCEMFAVVYVYGVDRFNKDIE 519

  Fly   459 FMMGIETGWYWRLCWRFITPGLMTAV------------LIYMLLDMSALEY---KGVGYPTLAHV 508
            ||:|.:...:|::.||.::|.:|..:            |:|.:.|.:..|:   :.:.||...:.
Mouse   520 FMIGHKPNIFWQVTWRVVSPLIMLVIFLFFFVIEVNKTLMYSIWDPNYEEFPKSQKIPYPNWVYA 584

  Fly   509 FGCFLATLGLIQLPGWAIYAIYKKRGHNGSFWQRIRAACKPSD 551
            ....:|.:..:.:|.:|||..             ||..|:.||
Mouse   585 VVVTVAGVPCLSIPCFAIYKF-------------IRNCCQKSD 614

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
List	NP_611364.2	SLC6sbd	19..489	CDD:271359	177/543 (33%)
Slc6a19	NP_083154.1	SLC5-6-like_sbd	32..612	CDD:294310	190/609 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810