Protein Alignment List and slc6a4b

DIOPT Version :9

• Sequence 1: NP_611364.2
• Gene: List / 37157
• FlyBaseID: FBgn0034381
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_001170930.1
• Gene: slc6a4b / 664770
• ZFINID: ZDB-GENE-060314-2
• Length: 591
• Species: Danio rerio
• Alignment Length: 552
• Identity: 190/552 - (34%)
• Similarity: 301/552 - (54%)
• Gaps: 32/552 - (5%)

  Fly    19 EQWGNGLEFLFSCISLSVGLGNIWRFPYIAFQNGGGTFVIPYLIALLVIGRPVYYLEISLGQFTG 83
            ::|...::||.|.|..:|.|||:||||||.:|||||.|:|||::..:..|.|::|:|::||||..
Zfish    39 DKWSKKMDFLLSVIGFAVDLGNVWRFPYICYQNGGGAFLIPYVLMAVFGGVPLFYMELALGQFHR 103

  Fly    84 RGVVKAF-DMAPLLKGVALGQVLATAASITYYSSIMALTLRFWLASFGSELPWSRCWESWGTDCH 147
            .|.:..: .:.|:.||:.....:.......||::|:|..|.::.:||.|.|||:.|...|.|:
Zfish   104 TGAISIWKHICPIFKGIGFAICIIALYVSFYYNTIIAWALFYFYSSFSSTLPWTSCDNDWNTE-- 166

  Fly   148 DGNAQNSSGK---------MSPAQLYFEREIL--HEVPNIDNGLSLPNWQLVACLAIAWLVIGGV 201
              |..|..||         .|||:.::.|.:|  ||...:.| :....|||:.||.:.:.::...
Zfish   167 --NCTNYFGKDNVTWTNYSRSPAEEFYTRNVLAVHESSGLGN-VGYIRWQLMLCLFLIFTIVYFS 228

  Fly   202 LIRGIKSSGKAAYFLGVFPYVVLLILLLRAVTLPGAIDGIIYFFKPQWRELLNPLVWYAAVTQVF 266
            |.:|:|:|||..:.....||||||||::|..|||||..|::::..|:|.:|....||..|..|:|
Zfish   229 LWKGVKTSGKVVWVTATLPYVVLLILMIRGATLPGAWKGVVFYLNPKWEKLKETSVWVDAAAQIF 293

  Fly   267 FSLAICFGTLITYASYNNFNRNVYNDIVIITTMDSCSSIIAGCITFGILGNLARETGNPDIGSVV 331
            |||...||.|:..:|||.|..|.|.|.::.:.::..:|.::|.:.|.:||.:| |..|.::..|.
Zfish   294 FSLGPGFGVLLALSSYNPFTNNCYRDAIVTSLVNCLTSFVSGFVIFTVLGYMA-EQRNVNVEDVA 357

  Fly   332 KG-GAGLAFISYPEAIAKFEYVPQMFAVLFFLMLFVLGIGSTVGMGSCILRVIRDQFGLRSPPIW 395
            :. |..|.||:||||||.. .....||::||:|:..||:.||.|....|:..:.|::    |.:.
Zfish   358 RDKGPSLLFITYPEAIANM-VGSTFFAIIFFVMMITLGLDSTFGGLEAIITAVMDEY----PDVL 417

  Fly   396 K-----LASGLTVLGFSVSIVYMTPGGQFILNLVDFYGVSFTALILAIGELVAVAWIYGVNRFCE 455
            .     ...||.|:.|..|:..:|.||.:::.|::.:||..:.:.:...|..||:|.||:|||..
Zfish   418 SHRRELFVLGLVVVCFLGSLSTLTKGGAYVVKLLEEFGVGSSIIAIVFLEATAVSWFYGINRFSN 482

  Fly   456 DIKFMMGIETGWYWRLCWRFITPGLMTAVLIYMLLDMSALEYKGVGYPTLAHVFGCFLATLGLIQ 520
            |||.|:|...|.:|::||..|:|..:..::|..||:...|......:|..:...|..:.....|.
Zfish   483 DIKSMLGYTPGLFWKVCWVAISPAFLAYIIISSLLNPQTLTLFDYEFPDWSITVGYIIGASSFIW 547

  Fly   521 LPGWAIYAIYKKRGHNGSFWQRIRAACKPSDT 552
            :|   ||.:||.....||..||:....:|..|
Zfish   548 IP---IYMVYKLVWTPGSLKQRLAVCLRPERT 576

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
List	NP_611364.2	SLC6sbd	19..489	CDD:271359	173/487 (36%)
slc6a4b	NP_001170930.1	SLC6sbd_SERT	38..574	CDD:271399	188/548 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820