Protein Alignment List and Slc6a19

DIOPT Version :10

• Sequence 1: NP_611364.2
• Gene: List / 37157
• FlyBaseID: FBgn0034381
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_001034811.2
• Gene: Slc6a19 / 664630
• RGDID: 1594328
• Length: 634
• Species: Rattus norvegicus
• Alignment Length: 642
• Identity: 200/642 - (31%)
• Similarity: 326/642 - (50%)
• Gaps: 109/642 - (16%)

  Fly     1 MTQLEISKKSEKPAEKPAEQWGNGLEFLFSCISLSVGLGNIWRFPYIAFQNGGGTFVIPYLIALL 65
            :.:||:.:| |:.:.:|  :|.|..:::.:|:...|||||:|||||:...:|||.|:||:||.|:
  Rat    18 LDELEVIEK-EEASSRP--KWDNKAQYMLTCVGFCVGLGNVWRFPYLCQSHGGGAFMIPFLILLV 79

  Fly    66 VIGRPVYYLEISLGQFTGRGVVKAF-DMAPLLKGVALGQVLATAASITYYSSIMALTLRFWLASF 129
            :.|.|:.:||.::||...:|.|..: .:.|.||||.:..:..:.....||::|:|..:.::..||
  Rat    80 LEGIPLLHLEFAIGQRLRKGSVGVWSSIHPALKGVGIASMFVSFMVGLYYNTIIAWVMWYFFNSF 144

  Fly   130 GSELPWSRCWESWGTDCHDGNAQNSSG------KMSPAQLYFEREILHEVPNIDNGLSLPNWQLV 188
            ...||||.|..:          ||.:|      |.|....::.||.|:...:|.:..|: .|.::
  Rat   145 QEPLPWSECPLN----------QNQTGYVEECAKSSSVDYFWYRETLNISTSISDSGSI-QWWIL 198

  Fly   189 ACLAIAWLVIGGVLIRGIKSSGKAAYFLGVFPYVVLLILLLRAVTLPGAIDGIIYFFKPQWRELL 253
            .||..||.|:....||||:::|||.|.....|||||.|.|:|.:||.||.:||::.|.|...||.
  Rat   199 LCLTCAWSVLYVCTIRGIETTGKAVYITSTLPYVVLTIFLIRGLTLKGATNGIVFLFTPNITELS 263

  Fly   254 NPLVWYAAVTQVFFSLAICFGTLITYASYNNFNRNVYNDIVIITTMDSCSSIIAGCITFGILGNL 318
            ||..|..|..|||:|.::.||.||:::|||:.:.|...|.||::.::..:|:.|..:.:.|:|..
  Rat   264 NPNTWLDAGAQVFYSFSLAFGGLISFSSYNSVHNNCEMDSVIVSIINGFTSVYAATVVYSIIGFR 328

  Fly   319 ARE----TGNPDIGSVVKG---------------------------------------------- 333
            |.|    ..|.:|.:::.|
  Rat   329 ATERFDDCVNTNILTLINGFDLPEGNVTAENFEAYQHWCNATNPEAYAQLTFQTCDINTFLSEGV 393

  Fly   334 -GAGLAFISYPEAIAKFEYVPQMFAVLFFLMLFVLGIGSTVGMGSCILRVIRDQFGLR-SPPIW- 395
             |.|||||.:.|||.|....| :::||||:|||.||:.|..|....::..::|   |. :|..|
  Rat   394 EGTGLAFIVFTEAITKMPVSP-LWSVLFFIMLFCLGLSSMFGNMEGVVVPLQD---LNITPKKWP 454

  Fly   396 -KLASGLTVLG-FSVSIVYMTPGGQFILNLVDFYGVSFTALILAIGELVAVAWIYGVNRFCEDIK 458
             :|.:||..|| :.::.::....||:.|:|:|.|..|...||:|..|:.||.::|||:||.:||:
  Rat   455 KELLTGLICLGTYLIAFIFTLNSGQYWLSLLDSYAGSIPLLIIAFCEMFAVVYVYGVDRFNKDIE 519

  Fly   459 FMMGIETGWYWRLCWRFITPGLMTAV------------LIYMLLDMSALEY---KGVGYPTLAHV 508
            ||:|.:...:|::.||.::|.:|..:            |:|.:.|....|:   :.|.||...:.
  Rat   520 FMIGHKPNIFWQVTWRVVSPLIMLVIFLFFFVIEVNKQLMYSVWDPDYEEFPKSQKVPYPDWVYA 584

  Fly   509 FGCFLATLGLIQLPGWAIYAIYKKRGHNGSFWQRIRAAC-KPSDTWGPANVQLDATI 564
            ....:|.:..:.:|.:|||.:             ||..| |..|..|..|....|::
  Rat   585 VVVIVAGVPCLTIPCFAIYKL-------------IRNYCQKSGDQHGLVNALSTASV 628

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
List	NP_611364.2	SLC6sbd	19..489	CDD:271359	177/543 (33%)
Slc6a19	NP_001034811.2	SLC5-6-like_sbd	32..612	CDD:444915	191/609 (31%)