Protein Alignment List and SLC6A13

DIOPT Version :9

• Sequence 1: NP_611364.2
• Gene: List / 37157
• FlyBaseID: FBgn0034381
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_057699.2
• Gene: SLC6A13 / 6540
• HGNCID: 11046
• Length: 602
• Species: Homo sapiens
• Alignment Length: 582
• Identity: 200/582 - (34%)
• Similarity: 312/582 - (53%)
• Gaps: 38/582 - (6%)

  Fly     6 ISKKSEKPAEKPAEQWGNGLEFLFSCISLSVGLGNIWRFPYIAFQNGGGTFVIPYLIALLVIGRP 70
            :.:|.|:........|.|.:||:.|.....:||||:|||||:.::||||.|.||||:.|...|.|
Human    20 VMEKKEEDGTLERGHWNNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYLVFLFTCGIP 84

  Fly    71 VYYLEISLGQFTGRGVVKAF-DMAPLLKGVALGQVLATAASITYYSSIMALTLRFWLASFGSELP 134
            |:.||.:|||:|.:|.|.|: .:.|:.:|:.....:.......||..::|..|.:..:||..:||
Human    85 VFLLETALGQYTSQGGVTAWRKICPIFEGIGYASQMIVILLNVYYIIVLAWALFYLFSSFTIDLP 149

  Fly   135 WSRCWESWGTDCHDGNAQNSSGKM--------SPAQLYFEREILHEVPNIDNG---LSLPNWQLV 188
            |..|:..|.|: |....|.::|.:        ||...::||.:|    .|.:|   |....|:|.
Human   150 WGGCYHEWNTE-HCMEFQKTNGSLNGTSENATSPVIEFWERRVL----KISDGIQHLGALRWELA 209

  Fly   189 ACLAIAWLVIGGVLIRGIKSSGKAAYFLGVFPYVVLLILLLRAVTLPGAIDGIIYFFKPQWRELL 253
            .||.:||::....:.:|:||:||..||...|||::|::||:|.||||||..||.::..|....|.
Human   210 LCLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLMLVVLLIRGVTLPGAAQGIQFYLYPNLTRLW 274

  Fly   254 NPLVWYAAVTQVFFSLAICFGTLITYASYNNFNRNVYNDIVIITTMDSCSSIIAGCITFGILGNL 318
            :|.||..|.||:|||.|||.|.|....|||.::.|.|.|.:.:..::|.:|.:||...|.|||.:
Human   275 DPQVWMDAGTQIFFSFAICLGCLTALGSYNKYHNNCYRDCIALCFLNSGTSFVAGFAIFSILGFM 339

  Fly   319 ARETGNPDIGSVVKGGAGLAFISYPEAIAKFEYVPQMFAVLFFLMLFVLGIGSTVGMGSCILRVI 383
            ::|.|.| |..|.:.|.|||||:||.|:....:.| ::|..||.|:.:||:.|.......::..:
Human   340 SQEQGVP-ISEVAESGPGLAFIAYPRAVVMLPFSP-LWACCFFFMVVLLGLDSQFVCVESLVTAL 402

  Fly   384 RDQFGLRSPPIWK-------LASGLTVLGFSVSIVYMTPGGQFILNLVDFYGVS-FTALILAIGE 440
            .|.:    |.:::       |..|::|:.|.|.::.:|.||.::..|.|:|..| ...|.:||.|
Human   403 VDMY----PHVFRKKNRREVLILGVSVVSFLVGLIMLTEGGMYVFQLFDYYAASGMCLLFVAIFE 463

  Fly   441 LVAVAWIYGVNRFCEDIKFMMGIETGWYWRLCWRFITPGLMTAVLIYMLLDMSALEY-KGVGYPT 504
            .:.|||:||..||.::|:.|:|.......:.||.|:||.:.||..::.|:..:.|.| |...||.
Human   464 SLCVAWVYGAKRFYDNIEDMIGYRPWPLIKYCWLFLTPAVCTATFLFSLIKYTPLTYNKKYTYPW 528

  Fly   505 LAHVFGCFLATLGLIQLPGWAIYAIYKKRGHNGSFWQRIRAACKPSDTW---GPANVQLDAT 563
            .....|..||...::.:|.|::|.:...:   |.|.:|||....|::..   .||.....||
Human   529 WGDALGWLLALSSMVCIPAWSLYRLGTLK---GPFRERIRQLMCPAEDLPQRNPAGPSAPAT 587

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
List	NP_611364.2	SLC6sbd	19..489	CDD:271359	176/489 (36%)
SLC6A13	NP_057699.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..22		0/1 (0%)
		SLC6sbd_GAT2	32..575	CDD:271396	194/556 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820