DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment List and si:ch211-225b11.1

DIOPT Version :9

Sequence 1:	NP_611364.2	Gene:	List / 37157	FlyBaseID:	FBgn0034381	Length:	564	Species:	Drosophila melanogaster
Sequence 2:	NP_001103931.1	Gene:	si:ch211-225b11.1 / 561694	ZFINID:	ZDB-GENE-060531-39	Length:	609	Species:	Danio rerio

Alignment Length:	550	Identity:	191/550 - (34%)
Similarity:	312/550 - (56%)	Gaps:	14/550 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 KSEKPAEKPAEQWGNGLEFLFSCISLSVGLGNIWRFPYIAFQNGGGTFVIPYLIALLVIGRPVYY 73
            |.|:.|.:|.|.||..|||:.:.|..:|||||:|||||:.:::|||.|:|||:|.|.:.|.|:.:
Zfish    45 KVEQQAAEPRETWGRRLEFVLATIGYAVGLGNVWRFPYLCYRSGGGAFLIPYMIMLFLCGIPLLF 109

  Fly    74 LEISLGQFTGRGVVKAF-DMAPLLKGVALGQVLATAASITYYSSIMALTLRFWLASFGSELPWSR 137
            :|.::||:|..|.|.|. .:.||.|||.|..|:.:....|||:.:|...|.:.|.||...|||..
Zfish   110 MEFTVGQYTRLGPVHALAQICPLFKGVGLATVVISYVLCTYYNVLMTWALYYLLHSFSPSLPWQS 174

  Fly   138 CWESWGT--DCHDGNAQNSSGKMSPAQLYFEREILHEVPNIDNGLSLPNWQLVACLAIAWLVIGG 200
            |..:|.|  :|..|...|::...|.:|.:|:.::|.....|:....: .|:|...|.:||.::..
Zfish   175 CNNTWNTVANCSTGFPGNATHLQSASQQFFDHKVLEMTSGIERAGGV-RWELFGLLVLAWGIVYF 238

  Fly   201 VLIRGIKSSGKAAYFLGVFPYVVLLILLLRAVTLPGAIDGIIYFFKPQWRELLNPLVWYAAVTQV 265
            .:.:|:||:||..||...|||.:|..||:..|.||||.:||::|..|.|.:||...||..|..|:
Zfish   239 CIFKGVKSTGKVVYFTATFPYFILFALLVNNVQLPGAKNGILFFLMPNWSKLLEVQVWVNAAAQI 303

  Fly   266 FFSLAICFGTLITYASYNNFNRNVYNDIVIITTMDSCSSIIAGCITFGILGNLARETGNPDIGSV 330
            |.|:.|.||::|:.||||.:|.|:..|..|::..:|.:||:||.:.|..:|.:| ...|..:..:
Zfish   304 FNSIGISFGSMISMASYNKYNNNILRDTFIVSLANSATSIVAGFVIFSAIGYMA-HIHNLPVDDI 367

  Fly   331 VKGGAGLAFISYPEAIAKFEYVPQMFAVLFFLMLFVLGIGSTVGMGSCILRVIRDQFGLRSPPIW 395
            ...|.||.|:.|||..:... |.|::|.|||:||..||:.|...|....:..|.|.||.::..::
Zfish   368 ATDGPGLVFVVYPEVFSTMP-VSQLWAPLFFIMLLCLGLDSQFAMVEVAVTFIMDGFGRKALKVF 431

  Fly   396 K----LASGLTVLGFSVSIVYMTPGGQFILNLVDFYGVSFTALILAIGELVAVAWIYGVNRFCED 456
            |    :...:...||.:.|.::|.||.::..|:|.|....:.:.||..|::||..|:||.|....
Zfish   432 KRKELIVLAVCSFGFLLGIPHITRGGIYVFQLMDHYTAVVSLMFLAFFEVLAVTLIFGVKRLSVM 496

  Fly   457 IKFMMGIETGWYWRLCWRFITPGLMTAVLIYMLLDMSALEY-KGVGYPTLAHVFGCFLATLGLIQ 520
            ::.|:|.:...::|:||::::|.|:..:||..::..:...| |...||..|.:.|.|::.:.:|.
Zfish   497 VENMLGKKPNLFFRICWQYLSPMLVLGILISSIVQYTPARYGKSYTYPLWAELLGWFISLVSIIW 561

  Fly   521 LPGWAIYAIYKKRGHNGSFWQRIRAACKPS 550
            :|..|::.::..   .||..||::.:..|:
Zfish   562 IPLGALHELWTT---EGSLLQRLKKSITPT 588

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
List	NP_611364.2	SLC6sbd	19..489	CDD:271359	172/476 (36%)
si:ch211-225b11.1	NP_001103931.1	SLC5-6-like_sbd	54..587	CDD:294310	186/538 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920