Protein Alignment List and slc6a22.2

DIOPT Version :9

• Sequence 1: NP_611364.2
• Gene: List / 37157
• FlyBaseID: FBgn0034381
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: XP_005166102.1
• Gene: slc6a22.2 / 561024
• ZFINID: ZDB-GENE-030616-628
• Length: 608
• Species: Danio rerio
• Alignment Length: 563
• Identity: 194/563 - (34%)
• Similarity: 304/563 - (53%)
• Gaps: 40/563 - (7%)

  Fly    12 KPAEKPAEQWGNGLEFLFSCISLSVGLGNIWRFPYIAFQNGGGTFVIPYLIALLVIGRPVYYLEI 76
            :|.....|||.|.||||.:.....:||||:|||||:.::||||.|.:||::.|...|.|:::||.
Zfish    22 RPKPPAREQWANKLEFLLAVAGHIIGLGNVWRFPYLCYKNGGGAFFVPYVLFLFTCGIPLFFLET 86

  Fly    77 SLGQFTGRGVVKAF-DMAPLLKGVALGQVLATAASITYYSSIMALTLRFWLASFGSELPWSRCWE 140
            ||||||.:|.:..: .:.||.:|:..|..:....:..||..|:|....:..:||.|||||:.|..
Zfish    87 SLGQFTSQGGITCWRKICPLFEGLGFGSQVVVLYTGVYYIIILAWAFLYLFSSFTSELPWASCNN 151

  Fly   141 SWGT-DCHDGNAQN----SSGK-MSPAQLYFEREIL------HEVPNIDNGLSLPNWQLVACLAI 193
            .|.| .|.:.:..|    |..| .||...::||.||      .::.|:       .|.|..||.:
Zfish   152 YWNTPSCMEFSESNITEYSPNKTTSPVIEFWERRILGLSGGIEQIGNV-------RWDLALCLLL 209

  Fly   194 AWLVIGGVLIRGIKSSGKAAYFLGVFPYVVLLILLLRAVTLPGAIDGIIYFFKPQWRELLNPLVW 258
            ||::....:.:|:||:||..||...|||::|::||:|.:||||||:||.::..|....|.:|.||
Zfish   210 AWIICYFCVWKGVKSTGKVVYFTATFPYLMLIVLLVRGLTLPGAINGITFYLYPDPSRLKDPQVW 274

  Fly   259 YAAVTQVFFSLAICFGTLITYASYNNFNRNVYNDIVIITTMDSCSSIIAGCITFGILGNLARETG 323
            ..|.:|:|:|..:|.|.|....|||.::.|.|.|.|.:..::|.:|.:||...|.:||.:|.|.|
Zfish   275 MDAGSQIFYSYGVCTGVLTALGSYNKYDNNCYRDCVYLCLLNSLTSFVAGFAIFSVLGFMADEQG 339

  Fly   324 NPDIGSVVKGGAGLAFISYPEAIAKFEYVPQMFAVLFFLMLFVLGIGSTVGMGSCILRVIRDQFG 388
             .||..|.:.|.|||||:||.|:|... :||::|:.||:|:..||:.|.......::..|.|.:
Zfish   340 -VDISLVAESGPGLAFIAYPRAVALMP-LPQLWAIFFFIMIIFLGLDSEFVYQEALVTSISDMY- 401

  Fly   389 LRSPPIWKLASGLTVL-------GFSVSIVYMTPGGQFILNLVDFYGVS-FTALILAIGELVAVA 445
               |..:::......|       .|.|.::.:|.||.::..|.|:|..| .|.|..||.:.:.|.
Zfish   402 ---PSFFQVGHRRKFLLLFICSASFFVGLLMVTEGGLYVFQLFDYYACSGMTLLTFAILQSICVG 463

  Fly   446 WIYGVNRFCEDIKFMMGIETGWYWRLCWRFITPGLMTAVLIYMLLDMSALEYKG-VGYPTLAHVF 509
            |:||.:|..:.::.|:|.....:.:.||:::||.:.|...|:.|:..:.|::.. ..||...:..
Zfish   464 WVYGADRHYDCVEDMIGYRPWPFMKCCWKYLTPAICTGTFIFSLVQYTPLKFNNEYEYPWWGYAI 528

  Fly   510 GCFLATLGLIQLPGWAIYAIYKKRGHN-GSFWQRIRAACKPSD 551
            |.|......:.:|.|.||.:    |.. ||..||:||.|.|::
Zfish   529 GGFFTLSSTLLVPLWMIYLV----GTTPGSMRQRVRALCTPAE 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
List	NP_611364.2	SLC6sbd	19..489	CDD:271359	174/490 (36%)
slc6a22.2	XP_005166102.1	SLC6sbd-TauT-like	28..565	CDD:271387	192/553 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820