Protein Alignment List and Slc6a16

DIOPT Version :9

• Sequence 1: NP_611364.2
• Gene: List / 37157
• FlyBaseID: FBgn0034381
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_001311464.1
• Gene: Slc6a16 / 381884
• MGIID: 2685930
• Length: 742
• Species: Mus musculus
• Alignment Length: 628
• Identity: 150/628 - (23%)
• Similarity: 271/628 - (43%)
• Gaps: 123/628 - (19%)

  Fly     1 MTQLE------ISKKSEKPAE--KPAEQWGNGLEFLFSCISLSVGLGNIWRFPYIAFQNGGGTFV 57
            :|.||      :::.|.:.:|  .|.:.|.:.:|::.:.:|..:....:.||.......|..:|.
Mouse   100 VTTLEQESSELVNRMSRESSEGYPPRQLWASKVEYMLAIMSYLLMPSGVLRFASGWVHKGSCSFF 164

  Fly    58 IPYLIALLVIGRPVYYLEISLGQFTGRGVVKAFDM----APLLKGVALGQVLATAASITYYSSIM 118
            |.|::.||.||.|:.:||:::||   |....:.||    :|...||....|:....:.||.:...
Mouse   165 IAYILMLLGIGIPLLFLEMAVGQ---RAQQSSADMWKNLSPWFGGVGYSMVMVCFITNTYLNVFN 226

  Fly   119 ALTLRFWLASFGSELPWSRCWESWGTDCHDGNAQNSSGKMSP------AQLYF-EREILHEVPNI 176
            :..|.:....|...:||.:|           ..|.:|....|      :..|| .|:.|.....|
Mouse   227 SWILFYMSHIFYFVVPWDQC-----------PLQRNSSNFDPECEQATSYTYFWYRKTLKASDRI 280

  Fly   177 DNGLSLPNWQLVACLAIAWLVIGGVLIRGIKSSGKAAYFLGVFPYVVLLILLLRAVTLPGAIDGI 241
            ::| ..|::.|...|.:::.:|...|:.||||.||..:.|.:.||.:::..|:|.:::.||..|:
Mouse   281 EDG-GQPSFSLGMSLFLSFCLICAFLVNGIKSIGKVLFVLLLVPYSIIVCFLIRTLSMDGAEYGL 344

  Fly   242 IYFFKPQWRELLNPLVWYAAVTQVFFSLAICFGTLITYAS----YNN-----FNRNVYNDIVIIT 297
            .:....:...:.:..:|..|..||.|.:.:.||.:::.||    :||     |...::..|.::.
Mouse   345 KHLLILKVASISDLTIWCHAGIQVLFDIGLGFGPIVSLASHVPDFNNCMADAFLMALFKIITLLM 409

  Fly   298 TMDSCSSIIA--------GC-----------ITFGILGNLARE---TGNPD-------------- 326
            |.....||:.        .|           :..|||...|:.   :|||.
Mouse   410 TTPFLLSILGFWATTTTHHCCKKNQETLLRLVAQGILPPDAQPPDLSGNPTSNYNSWLSSLPPPL 474

  Fly   327 ---IGSVV------------KGGAGLAFISYPEAIAKFEYVP--QMFAVLFFLMLFVLGIGSTV- 373
               :.|||            |......|:.:.|.|:   .:|  ..:.|||||:|..||:.|.:
Mouse   475 RSAVLSVVPECSVQKQFLKIKDNPRFLFLIFTEVIS---LLPGSGFWIVLFFLLLLTLGLCSNLM 536

  Fly   374 -GMGSCILRVIRDQFGL--RSPPIWKLASGLTVLGFSVSIVYMTPGGQFILNLVDFYGVSFTALI 435
             .:|:.:  .::|.|..  |.|.:  |...:::..|...::::.|.|.:..:|:....|:...:|
Mouse   537 FMLGNVL--TLQDTFPFCRRQPRL--LIVCVSMAMFLCGLIFIQPSGIYYFSLLSECWVAVPVII 597

  Fly   436 LAIGELVAVAWIYGVNRFCEDIKFMMG--IETGWYWRLCWRFITP----GLMTAV--------LI 486
            :.|.|.:||||.||.:||..|:..::|  |.:|..|  .|.:|:|    ||:|:|        |:
Mouse   598 IIICENLAVAWAYGADRFLADMVALLGRPIFSGCGW--LWCYISPMVVLGLLTSVFVYLVKGPLV 660

  Fly   487 YMLLDMSALEYKGVGYPTLAHVFGCFLATLGLIQLPGWAIYAI 529
            |...|.|..:.....:|..:.:....|....|:.:|.:.:|.:
Mouse   661 YFAWDSSTSKEVVRVFPEWSKILIAGLTVFVLMPIPAYFVYCL 703

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
List	NP_611364.2	SLC6sbd	19..489	CDD:271359	137/560 (24%)
Slc6a16	NP_001311464.1	SLC5-6-like_sbd	125..694	CDD:294310	142/592 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920