DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment List and CG1698

DIOPT Version :9

Sequence 1:	NP_611364.2	Gene:	List / 37157	FlyBaseID:	FBgn0034381	Length:	564	Species:	Drosophila melanogaster
Sequence 2:	NP_001260835.1	Gene:	CG1698 / 36006	FlyBaseID:	FBgn0033443	Length:	654	Species:	Drosophila melanogaster

Alignment Length:	554	Identity:	307/554 - (55%)
Similarity:	410/554 - (74%)	Gaps:	14/554 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 KPAEQWGNGLEFLFSCISLSVGLGNIWRFPYIAFQNGGGTFVIPYLIALLVIGRPVYYLEISLGQ 80
            |..:.|.|.:|||.|||:|||||||:||||:.|.:||||.|||||||.|:::|:||||||:.|||
  Fly    72 KKRDSWNNDIEFLMSCIALSVGLGNVWRFPFTALENGGGAFVIPYLIVLILVGKPVYYLEMLLGQ 136

  Fly    81 FTGRGVVKAFDMAPLLKGVALGQVLATAASITYYSSIMALTLRFWLASFGSELPWSRCWESWGTD 145
            |:.||.||.:|.:|:::|:..||||||....|||:::||||||:::.||...||||.|.|.|||:
  Fly   137 FSSRGSVKVYDFSPIMRGIGYGQVLATGIVTTYYATLMALTLRYFVDSFYPTLPWSYCREEWGTE 201

  Fly   146 CHDGNAQNSSG---------KMSPAQLYFEREILHEVPNIDNGLSLPNWQLVACLAIAWLVIGGV 201
            |.|...|.:|.         :.:.|:.||...||.|..:||:|:..|:|.|...||:||:||.|:
  Fly   202 CLDSGPQEASRATSLAGSGVRTTSAEFYFTNIILREKASIDDGIGYPSWSLALALAVAWIVIAGI 266

  Fly   202 LIRGIKSSGKAAYFLGVFPYVVLLILLLRAVTLPGAIDGIIYFFKPQWRELLNPLVWYAAVTQVF 266
            :.:|:||||||:|||.:|||||:|:||:||:|||||.||::||.:|||.:||.|.||||||||||
  Fly   267 MFKGVKSSGKASYFLALFPYVVMLVLLVRALTLPGAFDGVLYFLRPQWHKLLEPQVWYAAVTQVF 331

  Fly   267 FSLAICFGTLITYASYNNFNRNVYNDIVIITTMDSCSSIIAGCITFGILGNLARETGNPDIGSVV 331
            ||||||||.:|.|||||.|..|:|.|..|:||:|:.:|:::|.|.||||||||.|....||.|||
  Fly   332 FSLAICFGNIIMYASYNRFGHNIYRDANIVTTLDTFTSLLSGVIIFGILGNLAYENNTTDIASVV 396

  Fly   332 KGGAGLAFISYPEAIAKFEYVPQMFAVLFFLMLFVLGIGSTVGMGSCILRVIRDQFG-LRSPPIW 395
            .||.||||||||:|||||:::||:|:||||||||||||||.|||.||:..||:|||| |::   |
  Fly   397 NGGPGLAFISYPDAIAKFKWLPQLFSVLFFLMLFVLGIGSNVGMASCMSTVIKDQFGHLKN---W 458

  Fly   396 KLASGLTVLGFSVSIVYMTPGGQFILNLVDFYGVSFTALILAIGELVAVAWIYGVNRFCEDIKFM 460
            .:..|:.::|:.:.::|:||||||:|||||::||:|.||:|||.|||.:||||||.|.|.|::||
  Fly   459 TVVVGIAIVGYFLGLLYITPGGQFLLNLVDYFGVTFVALVLAIFELVTIAWIYGVKRLCRDVEFM 523

  Fly   461 MGIETGWYWRLCWRFITPGLMTAVLIYMLLDMSALEYKGVGYPTLAHVFGCFLATLGLIQLPGWA 525
            :||:|..|:|:||..:||.||..:|||.|:....|:||...|.:..:|||..|:..|:.|:..||
  Fly   524 IGIKTSLYYRICWAVVTPLLMLTILIYTLVLYEPLKYKDYTYQSGVYVFGWCLSAFGVGQVLFWA 588

  Fly   526 IYAIYKKRGHNGSFWQRIRAACKPSDTWGPANVQ 559
            |.|:.|:..|.| .|.|||.|.:|...|||::.|
  Fly   589 IPAVRKQPSHLG-LWARIRKAFEPLPNWGPSDPQ 621

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
List	NP_611364.2	SLC6sbd	19..489	CDD:271359	278/479 (58%)
CG1698	NP_001260835.1	SLC6sbd	75..552	CDD:271359	278/479 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469624
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D14202at7147
OrthoFinder	1	1.000	-	-		FOG0008552
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850