DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment List and CG13795

DIOPT Version :9

Sequence 1:	NP_611364.2	Gene:	List / 37157	FlyBaseID:	FBgn0034381	Length:	564	Species:	Drosophila melanogaster
Sequence 2:	NP_001285712.1	Gene:	CG13795 / 34049	FlyBaseID:	FBgn0031937	Length:	594	Species:	Drosophila melanogaster

Alignment Length:	583	Identity:	145/583 - (24%)
Similarity:	261/583 - (44%)	Gaps:	79/583 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 QWGNGLEFLFSC----ISLSVGLGNIWRFPYIAFQNG--GGTFVIPYLIALLVIGRPVYYLEISL 78
            :|....:|:|:|    :.|.|.:.:.|.|    |..|  |   ::||.:.:.:...|:..:...:
  Fly    22 KWDKPTDFMFACFGLALKLDVFVASFWMF----FDMGILG---ILPYFVYMSIYLVPIMVIHSFM 79

  Fly    79 GQFTGRGVVKAFDMAPLLKGVALGQVLATAASITYYSSIMALTLRFWLASFGSELPWSRC--WES 141
            |||:..|.:.||.::|..||:.......|.:.:.|||...|:.|.|.:.||...|||| |  ..|
  Fly    80 GQFSSSGFISAFRLSPFFKGMGYVSGFLTISMLIYYSIFAAVPLLFIINSFRPTLPWS-CEGLSS 143

  Fly   142 WGTDCHDGNAQNSSGKMS-------------------PAQLYFEREI----LHEVPNIDNGLSLP 183
            |    |:|:|..||....                   |:.|||:...    ...||:......|
  Fly   144 W----HNGSATLSSSCNKTLILEDFSEYNRSHQLLHVPSVLYFQNHYDSMQQDAVPDWYKDYEL- 203

  Fly   184 NWQLVACLAIAWLVIGGVLIRGIKSS--GKAAYFLGVFPYVVLLILLLRAVTLPGAIDGIIYFFK 246
            :|..|...||.|:||..:..:..:::  ||...::.:...|:||:..:|.:.||||::|:..:..
  Fly   204 SWHFVGLFAIIWVVIAFIFYKFSETAKFGKLIRYMVIVTLVLLLVCFVRFLFLPGALNGLHRYVT 268

  Fly   247 PQWRELLNPLVWYAAVTQVFFSLAICFGTLITYASYNNFNRNVYNDIVIITTMDSCSSIIAGCIT 311
            |:..::...:|  :....|..:....:|::||.:|:|.|..::.:...||:.......|:.|.::
  Fly   269 PKASDMAMGVV--STFIMVLHAFGAGWGSVITLSSFNGFKTDIMSYSWIISFGQIFIYIMFGMVS 331

  Fly   312 FGILGNLARETGN-PDIGSVVKGGAGLAFISYPEAIAKFEYVPQMFAVLFFLMLFVLGIGSTVGM 375
            | :|.:...|..: .|.|.|:  ...|.::|...|::...: |.::..:::.||.:..:......
  Fly   332 F-MLEHYFNELSDVDDNGHVL--SHWLLYLSSASALSTMAW-PNLWTFIYYSMLLIAALIVMTTQ 392

  Fly   376 GSCILRVIRDQFGL----RSPPIWKLASGLTVLGF----SVSIVYMTPGGQFILNLVDFYGVSFT 432
            ...:|:.:.|:|.:    :....:.|..|:.:..|    :..|::.:     .|.|...:..|..
  Fly   393 IFTVLQSLFDEFEVLRVRKQEVTFGLIGGIALCSFYFCTNHGIIFFS-----ALGLDAIFSHSLL 452

  Fly   433 ALILAIGELVAVAWIYGVNRFCEDIKFMMGIETGWYWRLCWRFITPGLMTAVLIYMLLDMSALEY 497
            .|:|    |:.|.||||..||..||:||:|.....:.....|||.|    .:|:..||...||..
  Fly   453 HLLL----LLVVLWIYGRERFQRDIEFMLGQPFASWKVFILRFIAP----IILVICLLAGIALSI 509

  Fly   498 KGVGY-PTLAHVFGCFLATLGLIQLPGWAIYAIYKKRGHNGSFWQRIRAACKPSDTWGPANVQ 559
            ....| .|:..|....|..|.::.:||:..|.:|:.   .|:|.:|.:..|:|:| |.|..::
  Fly   510 SEHSYSTTVVFVMSIVLVVLPILAIPGYGFYYLYQS---TGTFCERFKRTCRPTD-WYPVEME 568

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
List	NP_611364.2	SLC6sbd	19..489	CDD:271359	124/510 (24%)
CG13795	NP_001285712.1	SLC5-6-like_sbd	27..505	CDD:271356	125/509 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440794
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840