DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment List and CG13793

DIOPT Version :9

Sequence 1:	NP_611364.2	Gene:	List / 37157	FlyBaseID:	FBgn0034381	Length:	564	Species:	Drosophila melanogaster
Sequence 2:	NP_609136.2	Gene:	CG13793 / 34047	FlyBaseID:	FBgn0031935	Length:	583	Species:	Drosophila melanogaster

Alignment Length:	589	Identity:	142/589 - (24%)
Similarity:	255/589 - (43%)	Gaps:	76/589 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 AEKPAE------QWGNGLEFLFSCISLSVGLGNIWRFPYIAFQNGGGTFVIPYLIALLVIGRPVY 72
            |.||..      .|....:::|:|..|::.| :|:...:..|.|.|...::|||:.:::...|:.
  Fly     2 ASKPFSPDLNRGNWEKPTDYIFACFGLALKL-DIFVASFWFFFNTGIFGMVPYLMYMVIYLVPIM 65

  Fly    73 YLEISLGQFTGRGVVKAFDMAPLLKGVALGQVLATAASITYYSSIMALTLRFWLASFGSELPWSR 137
            .:...:|||:..|.:.||.::||.||:....:..|...:.||:...|:.|.|.|.||...||||
  Fly    66 VIHSYMGQFSSSGFISAFRLSPLFKGMGYVSLFLTITLLIYYTIFAAVPLLFVLNSFRPTLPWS- 129

  Fly   138 C--WESWGTD-------CHDGNAQNSSGKMSPAQLYFEREILHEVPNI----------DNGLSLP 183
            |  ::||..|       |:...|:..: |.:....||....:| ||::          .|...|.
  Fly   130 CEGFKSWQNDTIAKWSICNATIAEEVA-KETENDTYFYITNIH-VPSVLYFKSHFESFQNDSELN 192

  Fly   184 ----NWQLVACLAIAWLVIGGVLIRGIKSS--GKAAYFLGVFPYVVLLILLLRAVTLPGAIDGII 242
                :|.|....|:.|..|..:..:..:.:  ||...::.:....:||:..:|.:.||||..|:.
  Fly   193 DYEISWHLSGLFALVWATIAFIFYKFSEPAKFGKCIRYMVIGTVALLLVCFVRFLFLPGAHLGLK 257

  Fly   243 YFFKPQWRELLNPLVWYAAVTQVFFSLAI-----CFGTLITYASYNNFNRNVYNDIVIITTMDSC 302
            .:..|...|       :...|...|.:|:     .:|::||.:|:|.|..|:.:...||:.....
  Fly   258 NYMTPSIEE-------FVVGTSSTFIMALQAFGAGWGSVITLSSFNGFKTNIMSYSWIISFGQIF 315

  Fly   303 SSIIAGCITFGI------LGNLARETGNPDIGSVVKGGAGLAFISYPEAIAKFEYVPQMFAVLFF 361
            ..|:.|.::|.:      |.....||      .|:  ...:.|:|...|::...: |.::..:::
  Fly   316 IYIMFGMVSFMLEHYFLGLPKPLFET------QVI--NHWVLFLSSASALSSLGW-PNLWTFIYY 371

  Fly   362 LMLFVLGIGSTVGMGSCILRVIRDQFGLRSPPIWKLASGLTVLGFSV-SIVYMTPGGQFILNLVD 425
            .||.:..:.........||:.:.|:|........::..|| :.|.:| |:.:.|..|.....::.
  Fly   372 TMLLMAALIVITTQIFTILQSLFDEFEQLRAKKQEVTLGL-IGGLAVCSLYFCTNHGVLYFAILS 435

  Fly   426 FYGVSFTALILAIGELVAVAWIYGVNRFCEDIKFMMGIETGWYWRLCWRFITPGLMTAVLIYMLL 490
            ...: |:..:|.:..|:.|.|:||.:||.:|||||:|.....:.....||:.|  .|.|:..:|.
  Fly   436 IDAI-FSQTLLHLLLLLVVLWVYGRDRFQKDIKFMLGQPFASWKVFILRFVAP--PTLVICLVLE 497

  Fly   491 DMSALEYKGVGYPTLAHVFGCFLATLGLIQLPGWAIYAIYKKRGHNGSFWQRIRAACKPSDTWGP 555
            ....||........| |.....|..|.::.:|.:..|.|:::   .||..:..||.     .|.|
  Fly   498 IKMCLEEHSYSSSVL-HFMAIILVGLPILAIPAYGFYYIHQR---PGSISELFRAT-----DWYP 553

  Fly   556 ANVQ 559
            ..::
  Fly   554 VEME 557

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
List	NP_611364.2	SLC6sbd	19..489	CDD:271359	123/512 (24%)
CG13793	NP_609136.2	SLC5-6-like_sbd	19..498	CDD:271356	123/502 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440796
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840