Protein Alignment List and Slc6a15

DIOPT Version :9

• Sequence 1: NP_611364.2
• Gene: List / 37157
• FlyBaseID: FBgn0034381
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_001239259.1
• Gene: Slc6a15 / 103098
• MGIID: 2143484
• Length: 729
• Species: Mus musculus
• Alignment Length: 623
• Identity: 191/623 - (30%)
• Similarity: 312/623 - (50%)
• Gaps: 125/623 - (20%)

  Fly     5 EISKK------------------SEKPAEKPAEQWGNGLEFLFSCISLSVGLGNIWRFPYIAFQN 51
            |:|||                  ||...|:||  |.:.|:::.:.:..||||||:|||||:..:|
Mouse    32 EVSKKSELIVDVQEEKDTDAEDGSEADDERPA--WNSKLQYILAQVGFSVGLGNVWRFPYLCQKN 94

  Fly    52 GGGTFVIPYLIALLVIGRPVYYLEISLGQFTGRGVVKAFD-MAPLLKGVALGQVLATAASITYYS 115
            |||.:::||||.|||||.|:::||:|:||...||.:..:: ::|.|.|:.....:.......||:
Mouse    95 GGGAYLLPYLILLLVIGIPLFFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYN 159

  Fly   116 SIMALTLRFWLASFGSELPWSRCWESWGTDCHDGNAQNSS--------GKMSPAQLYFEREILHE 172
            .|:..||.::..||...|||.:|          ...:|:|        .:.|....|:.||.|..
Mouse   160 VIIGWTLFYFSQSFQQPLPWDQC----------PLVKNASHTYVEPECEQSSATTYYWYREALDI 214

  Fly   173 VPNIDNGLSLPNWQLVACLAIAWLVIGGVLIRGIKSSGKAAYFLGVFPYVVLLILLLRAVTLPGA 237
            ..:|.:...| ||::..||.:||:::...:|:||:||||..||..:||||||:..|:|::.|.|:
Mouse   215 TSSISDSGGL-NWKMTVCLLVAWVMVCLAMIKGIQSSGKIMYFSSLFPYVVLICFLIRSLLLNGS 278

  Fly   238 IDGIIYFFKPQWRELLNPLVWYAAVTQVFFSLAICFGTLITYASYNNFNRNVYNDIVIITTMDSC 302
            ||||.:.|.|:...:|.|.||..|.|||||:|.:.||.:|.::|||..:.|.:.|.|:::.::..
Mouse   279 IDGIRHMFTPKLEMMLEPKVWREAATQVFFALGLGFGGVIAFSSYNKRDNNCHFDAVLVSFINFF 343

  Fly   303 SSIIAGCITFGILG---NLARE---------------TGN------P-----------------D 326
            :|::|..:.|.:||   |:..|               .||      |                 |
Mouse   344 TSVLATLVVFAVLGFKANIVNEKCISQNSEMILKLLKMGNISWDVIPHHINLSAVTVEDYRLVYD 408

  Fly   327 IGSVVK----------------------GGAGLAFISYPEAIAKFEYVPQMFAVLFFLMLFVLGI 369
            |...||                      .|.|||||::.||:..|...| .::|:|||||..||:
Mouse   409 IIQKVKEEEFAVLHLNACQIEDELNKAVQGTGLAFIAFTEAMTHFPASP-FWSVMFFLMLINLGL 472

  Fly   370 GSTVGMGSCILRVIRDQFGLRSPPIWKLASGLTVLGFSVSIVYMTPGGQFILNLVDFYGVSFTAL 434
            ||..|....|:..|.|.|.:|...:..:.   .:|.|.:.::::...|.:.:.:.|.|..:...|
Mouse   473 GSMFGTIEGIITPIVDTFKVRKEILTVIC---CLLAFCIGLIFVQRSGNYFVTMFDDYSATLPLL 534

  Fly   435 ILAIGELVAVAWIYGVNRFCEDIKFMMGIETGWYWRLCWRFITPGLMTAVLIYMLLDM------- 492
            |:.|.|.:||:::||:::|.||:..|:|.....|:...|::|:|.::..:||..:::|
Mouse   535 IVVILENIAVSFVYGIDKFIEDLTDMLGFAPSKYYYYMWKYISPLMLLTLLIASIVNMGLSPPGY 599

  Fly   493 -------SALEYKGVGYPTLAHVFGCF-LATLGLIQLP 522
                   ::.|:  :.||....|. || |..|.::.:|
Mouse   600 NAWIKEKASEEF--LSYPMWGMVV-CFSLMVLAILPVP 634

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
List	NP_611364.2	SLC6sbd	19..489	CDD:271359	172/541 (32%)
Slc6a15	NP_001239259.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	42..61		2/18 (11%)
		SLC6sbd_SBAT1	61..640	CDD:212091	184/594 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910