Protein Alignment List and slc6a4l

DIOPT Version :10

• Sequence 1: NP_611364.2
• Gene: List / 37157
• FlyBaseID: FBgn0034381
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: XP_012825214.2
• Gene: slc6a4l / 100496361
• XenbaseID: XB-GENE-981144
• Length: 590
• Species: Xenopus tropicalis
• Alignment Length: 564
• Identity: 199/564 - (35%)
• Similarity: 308/564 - (54%)
• Gaps: 38/564 - (6%)

  Fly    19 EQWGNGLEFLFSCISLSVGLGNIWRFPYIAFQNGGGTFVIPYLIALLVIGRPVYYLEISLGQFTG 83
            ::|...::||.|.|..:|.|||:||||||.:|||||.|:|||.|..:..|.|::|:|::||||..
 Frog    38 DKWSKKMDFLLSVIGFAVDLGNVWRFPYICYQNGGGAFLIPYTIMAIFGGVPLFYMELALGQFHR 102

  Fly    84 RGVVKAFD-MAPLLKGVALGQVLATAASITYYSSIMALTLRFWLASFGSELPWSRCWESWGTDCH 147
            .|.:..:. :.|:.||:.....:.......||::|:|..|.::.:||...|||:.|...|.|.
 Frog   103 MGAIPIWKRICPIFKGIGFAICIIALYVSFYYNTIIAWALFYFYSSFTETLPWTNCDNPWNTP-- 165

  Fly   148 DGNAQNSSGK---------MSPAQLYFEREIL--HEVPNIDN--GLSLPNWQLVACLAIAWLVIG 199
              |..|..|:         .|||:.::.|::|  ||...:||  ||   .|||:.||.|.:.::.
 Frog   166 --NCTNYFGRSNITWNNYSKSPAEEFYTRKVLGIHEAEGLDNVGGL---RWQLILCLFIIFTIVY 225

  Fly   200 GVLIRGIKSSGKAAYFLGVFPYVVLLILLLRAVTLPGAIDGIIYFFKPQWRELLNPLVWYAAVTQ 264
            ..|.:|:|:|||..:.....|||||||||:|..|||||..||:::.:|:|.:|::..||..|..|
 Frog   226 FSLWKGVKTSGKVVWVTATLPYVVLLILLIRGATLPGAWRGILFYLRPKWEKLMDTAVWVDAAAQ 290

  Fly   265 VFFSLAICFGTLITYASYNNFNRNVYNDIVIITTMDSCSSIIAGCITFGILGNLARETGNPDIGS 329
            :||||...||.|:..:|||.|:.|.|.|.:|.:|::..:|.::|.:.|.:||.:|...| .::..
 Frog   291 IFFSLGPGFGVLLALSSYNPFHNNCYRDALITSTVNCLTSFVSGFVIFTVLGYMAEMRG-VEVED 354

  Fly   330 VVKG-GAGLAFISYPEAIAKFEYVPQMFAVLFFLMLFVLGIGSTVGMGSCILRVIRDQFGLRSPP 393
            |.|. |..|.||:||||||.. .....||::||||:..||:.||.|....|:..:.|::    |.
 Frog   355 VAKDKGPSLLFITYPEAIANM-VGSTFFAIIFFLMMITLGLDSTFGGLEAIITAVMDEY----PH 414

  Fly   394 IWKLASGLTVLG-----FSVSIVYMTPGGQFILNLVDFYGVSFTALILAIGELVAVAWIYGVNRF 453
            |......|.|||     |:.|:..:|.||.:::.|::.:|.....:.:...|.:||:|.||:.||
 Frog   415 ILSKRRELFVLGLVIVCFTGSLSTLTYGGAYVVKLLEQFGAGCPIIAVVFLEAIAVSWFYGIQRF 479

  Fly   454 CEDIKFMMGIETGWYWRLCWRFITPGLMTAVLIYMLLDMSALEYKGVGYPTLAHVFGCFLATLGL 518
            ..|:|.|:|...|.:||:||..|:|..:..:::..|:|...|......||......|..:.....
 Frog   480 SNDVKSMLGFVPGIFWRICWVAISPAFLAFIIVSSLMDQPPLILFDYQYPKWTVSVGFLIGASSF 544

  Fly   519 IQLPGWAIYAIYKKRGHNGSFWQRIRAACKPSDTWGPANVQLDA 562
            |.:|   :|.:||.....||..:|:....:|..|  ..:.|||:
 Frog   545 IWIP---VYMVYKLVWTPGSLKERLAVCVRPEKT--VRDQQLDS 583

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
List	NP_611364.2	SLC6sbd	19..489	CDD:271359	180/489 (37%)
slc6a4l	XP_012825214.2	SLC5-6-like_sbd	37..573	CDD:444915	194/550 (35%)