Protein Alignment List and slc6a6

DIOPT Version :9

• Sequence 1: NP_611364.2
• Gene: List / 37157
• FlyBaseID: FBgn0034381
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: XP_017949178.2
• Gene: slc6a6 / 100494063
• XenbaseID: XB-GENE-991256
• Length: 616
• Species: Xenopus tropicalis
• Alignment Length: 570
• Identity: 193/570 - (33%)
• Similarity: 311/570 - (54%)
• Gaps: 46/570 - (8%)

  Fly    12 KPAEKPAEQWGNGLEFLFSCISLSVGLGNIWRFPYIAFQNGGGTFVIPYLIALLVIGRPVYYLEI 76
            ||.::  |:|.:.::|:.|.....:||||:|||||:.::||||.|:|||.|.|...|.||::||:
 Frog    37 KPPQR--EKWASKIDFVLSVAGGFIGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGGGLPVFFLEV 99

  Fly    77 SLGQFTGRGVVKAFD-MAPLLKGVALGQVLATAASITYYSSIMALTLRFWLASFGSELPWSRCWE 140
            .|||||..|.:..:: :.|:..|:....::..:....||..|:|..:.:...||..:|||:.|.:
 Frog   100 VLGQFTSEGGITCWEKICPVFTGIGYASIVIVSLLNVYYIVILAWGVYYLFQSFQGQLPWALCHQ 164

  Fly   141 SWGTD-CHDGN---------AQNSSGKMSPAQLYFEREILHEVPNIDNGLSLPNWQLVACLAIAW 195
            .|.|: |.:..         :.||:...||...::|.::|.....||: :.:..|.|..||.:.|
 Frog   165 PWNTESCVEDTFRKNWTMWMSMNSTNFTSPVTEFWEHKVLSLSKGIDD-VGVLKWDLALCLLLTW 228

  Fly   196 LVIGGVLIRGIKSSGKAAYFLGVFPYVVLLILLLRAVTLPGAIDGIIYFFKPQWRELLNPLVWYA 260
            ::....:.:|::|:||..||...||:::||:||:|.||||||.:||.::..|....|.:|.||..
 Frog   229 VICFFCIWKGVRSTGKVVYFTATFPFIMLLVLLIRGVTLPGAAEGIKFYLYPDITRLADPQVWID 293

  Fly   261 AVTQVFFSLAICFGTLITYASYNNFNRNVYNDIVIITTMDSCSSIIAGCITFGILGNLARETGNP 325
            |.||:|||.|||.|.:.:..|||.:..|.|.|.:::..::|.:|.::|...|.:||.:|:|.| .
 Frog   294 AGTQIFFSYAICLGAMTSLGSYNKYKYNCYRDCMLLGCLNSGTSFVSGFAIFSVLGFMAQEQG-V 357

  Fly   326 DIGSVVKGGAGLAFISYPEAIAKFEYVPQMFAVLFFLMLFVLG-----------IGSTVGMGSCI 379
            ||..|.:.|.|||||:||:|::... :|..:|:|||:||.:||           |.|.|.:....
 Frog   358 DIADVAESGPGLAFIAYPKAVSMMP-LPSFWAILFFIMLLLLGLDSQFVEVEGQITSLVDLYPSF 421

  Fly   380 LR--VIRDQFGLRSPPIWKLASGLTVLGFSVSIVYMTPGGQFILNLVDFYGVSFTALI-LAIGEL 441
            ||  ..|:.|          .:.:..|.:.:.:..:|.||.::..|.|:|..|...|: :|..|.
 Frog   422 LRKGYRREIF----------IAVVCFLSYLLGLTMVTEGGMYVFQLFDYYAASGVCLLWVAFFEC 476

  Fly   442 VAVAWIYGVNRFCEDIKFMMGIETGWYWRLCWRFITPGLMTAVLIYMLLDMSALEY-KGVGYPTL 505
            |||||:||.::|.::|:.|:|.:.|.:.:..|..|||.|..|..|:.|...:.|.| |...||..
 Frog   477 VAVAWVYGADKFYDNIEDMIGYKPGPWMKWSWTVITPLLCVACFIFSLAKYTPLTYNKYYVYPDW 541

  Fly   506 AHVFGCFLATLGLIQLPGWAIYAIYKKRGHNGSFWQRIRAACKPSDT--W 553
            |...|..||...:|.:|...::.|.:.   :||..:||:|...|.:.  |
 Frog   542 AIGLGWVLALSSMICIPLVVVFHIVRS---DGSLIERIKAVTAPREVNRW 588

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
List	NP_611364.2	SLC6sbd	19..489	CDD:271359	171/494 (35%)
slc6a6	XP_017949178.2	SLC6sbd_TauT	41..582	CDD:271398	189/558 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920