Protein Alignment List and slc6a17

DIOPT Version :10

• Sequence 1: NP_611364.2
• Gene: List / 37157
• FlyBaseID: FBgn0034381
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: XP_002933031.1
• Gene: slc6a17 / 100490416
• XenbaseID: XB-GENE-964419
• Length: 725
• Species: Xenopus tropicalis
• Alignment Length: 615
• Identity: 182/615 - (29%)
• Similarity: 309/615 - (50%)
• Gaps: 110/615 - (17%)

  Fly     3 QLEISKKSEKPAEKPAEQWGNGLEFLFSCISLSVGLGNIWRFPYIAFQNGGGTFVIPYLIALLVI 67
            |||.|.:.|   ::||  |.|.|:::.:.|..||||||:|||||:..:||||.:::||||.|::|
 Frog    49 QLEDSSELE---DRPA--WNNKLQYILAQIGYSVGLGNVWRFPYLCQKNGGGAYMVPYLILLIII 108

  Fly    68 GRPVYYLEISLGQFTGRGVVKAFD-MAPLLKGVALGQVLATAASITYYSSIMALTLRFWLASFGS 131
            |.|:::||:::||...||.:..:: :.|.|.|:.....:.......||:.|:..::.::..||..
 Frog   109 GIPLFFLELAVGQRIRRGSIGVWNYICPRLGGIGYASCVVCFFVGLYYNVIIGWSIFYFFQSFQY 173

  Fly   132 ELPWSRCWESWGTDCHDGNAQNSS--------GKMSPAQLYFEREILHEVPNIDNGLSLPNWQLV 188
            .|||:.|          ...:|.|        .|.|....::.||.|....:|..|..| ||::.
 Frog   174 PLPWNEC----------PTVKNGSVNVVEAECDKSSATTFFWYREALDISNSISEGGGL-NWKMT 227

  Fly   189 ACLAIAWLVIGGVLIRGIKSSGKAAYFLGVFPYVVLLILLLRAVTLPGAIDGIIYFFKPQWRELL 253
            .||.:||.::...:|:||:||||..||..:||||||:..|:|.:.|.|::|||::...|:..::|
 Frog   228 LCLLVAWTMVCMAMIKGIQSSGKVMYFSSLFPYVVLICFLIRGLFLRGSVDGILHMLTPKVEKML 292

  Fly   254 NPLVWYAAVTQVFFSLAICFGTLITYASYNNFNRNVYNDIVIITTMDSCSSIIAGCITFGILG-- 316
            :|.||..|.|||||:|.:.||.:|.::|||..:.|...|..:::.::..:|::|..:.|.:||
 Frog   293 DPQVWREAATQVFFALGLGFGGVIAFSSYNKQDNNCQFDAALVSFINFFTSVLATLVVFAVLGFK 357

  Fly   317 -NLARE---------------TGNPDIG--------------------SVVK------------- 332
             |:..|               |.:.|..                    .|:|
 Frog   358 ANVMNEKCVVQNAEKILGYINTHDIDYSLIPPHVNFSHLTTEDYAKMYQVIKTVKEDHFQDLHLD 422

  Fly   333 ------------GGAGLAFISYPEAIAKFEYVPQMFAVLFFLMLFVLGIGSTVGMGSCILRVIRD 385
                        .|.|||||::.||:..|...| .::|:||.||..||:||.:|..|.|:..|.|
 Frog   423 ACVLEDELDKAVQGTGLAFIAFTEAMTHFPASP-FWSVMFFFMLINLGLGSMIGTMSGIITPIID 486

  Fly   386 QFGLRSPPIWKLASGLTVLGFSVSIVYMTPGGQFILNLVDFYGVSFTALILAIGELVAVAWIYGV 450
            .|.:|..   .|.....::.|.:.::::...|.:.:|:.|.|..:....|:.|.|.:||||:||.
 Frog   487 TFKVRKE---ILTVSCCIVAFLLGLIFVQRSGNYFVNMFDDYSATLPLTIVVILENIAVAWVYGT 548

  Fly   451 NRFCEDIKFMMGIETGWYWRLCWRFITP----GLMTAVLIYM----------LLDMSALEYKGVG 501
            .:|.:::..|:|.....|:...|::::|    .|:||.:|.:          :.:::|.::  |.
 Frog   549 KKFMQELTEMLGFRPYSYYFYSWKYVSPIFMAILLTASVIQLGISPPGYSAWIRELAAEQF--VL 611

  Fly   502 YPTLAHVFGCFLATLGLIQLPGWAIYAIYK 531
            |||.|......|..|.::.:|  .|:.:::
 Frog   612 YPTWALSLLITLIILAILPVP--VIFILWQ 639

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
List	NP_611364.2	SLC6sbd	19..489	CDD:271359	165/555 (30%)
slc6a17	XP_002933031.1	SLC6sbd_NTT4	59..647	CDD:271403	177/602 (29%)