Protein Alignment List and slc6a8

DIOPT Version :9

• Sequence 1: NP_611364.2
• Gene: List / 37157
• FlyBaseID: FBgn0034381
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: XP_002935539.1
• Gene: slc6a8 / 100489909
• XenbaseID: XB-GENE-986840
• Length: 644
• Species: Xenopus tropicalis
• Alignment Length: 566
• Identity: 200/566 - (35%)
• Similarity: 313/566 - (55%)
• Gaps: 34/566 - (6%)

  Fly    19 EQWGNGLEFLFSCISLSVGLGNIWRFPYIAFQNGGGTFVIPYLIALLVIGRPVYYLEISLGQFTG 83
            :.|.:.::|:.||:..:|||||:|||||:.::||||.|:|||::..::.|.|:::|||:||||..
 Frog    59 DTWTSQMDFIMSCVGFAVGLGNVWRFPYLCYKNGGGVFLIPYILIAILGGIPIFFLEIALGQFMK 123

  Fly    84 RGVVKAFDMAPLLKGVALGQVLATAASITYYSSIMALTLRFWLASFGSELPWSRCWESWGT---- 144
            .|.:..:::|||.:|:....|:......|||..|:...:.:.:.||.:.||||.|..:|.:
 Frog   124 AGSIAVWNIAPLFQGIGFASVVIVFFCNTYYILILTWGVYYLVKSFSAVLPWSHCNNTWNSPDCV 188

  Fly   145 ------DCHDGNAQNSSG---------KMSPAQLYFEREILHEVPNIDNGLSLPNWQLVACLAIA 194
                  ||.:|.|.::.|         |:||...::|:::|.....:|:..|: ||:|:.||...
 Frog   189 DIFRQEDCTNGTANSTFGNLTCNELADKVSPITEFWEKKVLRLSSGLDDIGSI-NWELLLCLIGC 252

  Fly   195 WLVIGGVLIRGIKSSGKAAYFLGVFPYVVLLILLLRAVTLPGAIDGIIYFFKPQWRELLNPLVWY 259
            ||::...:.:|:||:||..||...||||||||||:|...||||.:||||:.||.|.:|....||.
 Frog   253 WLLVYFCVWKGVKSTGKIVYFTATFPYVVLLILLVRGAMLPGATEGIIYYLKPDWSKLGTAQVWI 317

  Fly   260 AAVTQVFFSLAICFGTLITYASYNNFNRNVYNDIVIITTMDSCSSIIAGCITFGILGNLARETGN 324
            .|.||:|||.||..|.|....|||.||.:.|.|..|:..::|.:|..||.:.|.|||.:|.|.|
 Frog   318 DAGTQIFFSYAIGLGALTALGSYNRFNNDCYKDAFILAVINSGTSFFAGFVVFSILGFMANEQG- 381

  Fly   325 PDIGSVVKGGAGLAFISYPEAIAKFEYVPQMFAVLFFLMLFVLGIGS----TVGMGSCILRVIRD 385
            .||..|.:.|.|||||:||.|::.....| :::.|||.||.:||:.|    ..|:.:.||.::..
 Frog   382 VDISKVAESGPGLAFIAYPRAVSLMPVAP-LWSALFFFMLLLLGLDSQFVGVEGLITAILDLLPA 445

  Fly   386 QFGLRSPPIWKLASGLTVLGFSVSIVYMTPGGQFILNLVDFYGVS-FTALILAIGELVAVAWIYG 449
            ::..|......:|....:: |.:.:..:|.||.::..|.|:|..| .|.|.....:.|.|||:||
 Frog   446 RYYFRFQREIAVAICCAIM-FLIDLSMLTEGGMYVFQLFDYYSASGMTLLWQTFWQCVVVAWVYG 509

  Fly   450 VNRFCEDIKFMMGIETGWYWRLCWRFITPGLMTAVLIYMLLDMSALEY-KGVGYPTLAHVFGCFL 513
            .:||.:||..|:|.....:.:.||.|:||.:..|:.::.|::...|.| ....||......|...
 Frog   510 ADRFMDDIARMIGYRPFPWMKWCWSFVTPFVCMAIFLFNLINYKPLTYNNSYTYPWWGEAIGWGF 574

  Fly   514 ATLGLIQLPGWAIYAIYKKRGHNGSFWQRIRAACKPSDTWGPANVQ 559
            |...::.:|...:|.|...:|.....||.:   .||  .||..:::
 Frog   575 ALSSMLCVPVTFLYKITCAKGSLRERWQHL---TKP--IWGAHHLE 615

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
List	NP_611364.2	SLC6sbd	19..489	CDD:271359	183/493 (37%)
slc6a8	XP_002935539.1	SLC5-6-like_sbd	58..644	CDD:382020	200/566 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820