Protein Alignment List and slc6a3

DIOPT Version :9

• Sequence 1: NP_611364.2
• Gene: List / 37157
• FlyBaseID: FBgn0034381
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: XP_002933174.1
• Gene: slc6a3 / 100488824
• XenbaseID: XB-GENE-982873
• Length: 621
• Species: Xenopus tropicalis
• Alignment Length: 546
• Identity: 201/546 - (36%)
• Similarity: 309/546 - (56%)
• Gaps: 23/546 - (4%)

  Fly    19 EQWGNGLEFLFSCISLSVGLGNIWRFPYIAFQNGGGTFVIPYLIALLVIGRPVYYLEISLGQFTG 83
            |.|...::||.|.|..:|.|.|:|||||:.::||||.|::||:..:::.|.|::|:|::||||..
 Frog    61 ETWSKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYIFFMVIAGMPLFYMELALGQFNR 125

  Fly    84 RGVVKAFDMAPLLKGVALGQVLATAASITYYSSIMALTLRFWLASFGSELPWSRCWESWGT-DCH 147
            .|....:.:.|:.|||....:|.:.....:|:.|:|..|::..:||.|||||..|..||.: :|.
 Frog   126 EGAAGVWKICPIFKGVGYTVILISLYVGFFYNVIIAWALQYLFSSFTSELPWIHCNNSWNSPNCS 190

  Fly   148 DGNAQNSSG----------KMSPAQLYFEREI--LHEVPNIDNGLSLPNWQLVACLAIAWLVIGG 200
            :....|.|.          |::||..||||.:  |||...| :.|..|.|:|.:||.:..:.:..
 Frog   191 ETKYSNFSDYSLFGLNDTYKVTPAAEYFERGVLHLHESQGI-HDLGSPRWKLTSCLIVVIVFLYF 254

  Fly   201 VLIRGIKSSGKAAYFLGVFPYVVLLILLLRAVTLPGAIDGIIYFFKPQWRELLNPLVWYAAVTQV 265
            .|.:|:|:|||..:.....|||||..||||.||||||||||..:....:..|....||..|.||:
 Frog   255 SLWKGVKTSGKVVWITATMPYVVLTALLLRGVTLPGAIDGIKAYLSVDFLRLCEASVWIDAATQI 319

  Fly   266 FFSLAICFGTLITYASYNNFNRNVYNDIVIITTMDSCSSIIAGCITFGILGNLARETGNPDIGSV 330
            .|||.:.||.||.::|||.|..|.|.|.:|.|:::|.:|..:|.:.|..||.:|::...| ||.|
 Frog   320 CFSLGVGFGVLIAFSSYNKFTNNCYRDAIITTSVNSLTSFFSGFVIFSFLGYMAQKHNVP-IGDV 383

  Fly   331 VKGGAGLAFISYPEAIAKFEYVPQMFAVLFFLMLFVLGIGSTVGMGSCILRVIRDQFGL--RSPP 393
            .|.|.||.||.||||||... :..:::|:||:||..|||.|.:|....::..:.|:|..  |...
 Frog   384 AKDGPGLIFIIYPEAIATLP-LSSVWSVIFFIMLLTLGIDSAMGGMESVITGLIDEFKFLRRHRE 447

  Fly   394 IWKLASGLTVLGFSVSIVYMTPGGQFILNLVDFYGVSFTALILAIGELVAVAWIYGVNRFCEDIK 458
            ::.|.  :.:..|..|:..:|.||.::..|:|.:....:.|...:.|.:.:||.|||.||.:||:
 Frog   448 LFTLF--IVLCTFFTSLSCVTNGGIYVFTLLDHFAAGTSILFGVLIEAIGIAWFYGVGRFSDDIE 510

  Fly   459 FMMGIETGWYWRLCWRFITPGLMTAVLIYMLLDMSALEYKGVGYPTLAHVFGCFLATLGLIQLPG 523
            .|:|...|.||||||:|::|..:..|::..::...:.:|....:|..|:|.|..:|...:..:|
 Frog   511 EMIGKRPGLYWRLCWKFVSPCFLLFVVVVSIVTYRSPKYGNYTFPEWANVIGWLVAISSMAMVP- 574

  Fly   524 WAIYAIYKKRGHNGSFWQRIRAACKP 549
              :|||||....:|||.::|..|..|
 Frog   575 --LYAIYKFSSLHGSFREKIAYAITP 598

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
List	NP_611364.2	SLC6sbd	19..489	CDD:271359	183/484 (38%)
slc6a3	XP_002933174.1	SLC6sbd_DAT1	60..615	CDD:212083	201/546 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010