Protein Alignment List and slc6a2

DIOPT Version :9

• Sequence 1: NP_611364.2
• Gene: List / 37157
• FlyBaseID: FBgn0034381
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: XP_017948962.2
• Gene: slc6a2 / 100486589
• XenbaseID: XB-GENE-486549
• Length: 624
• Species: Xenopus tropicalis
• Alignment Length: 563
• Identity: 202/563 - (35%)
• Similarity: 312/563 - (55%)
• Gaps: 23/563 - (4%)

  Fly     5 EISKKSEKPAE--KPAEQWGNGLEFLFSCISLSVGLGNIWRFPYIAFQNGGGTFVIPYLIALLVI 67
            ::|.:.|.|.|  :..||||..::||.|.:..||.|.|:||||::.::||||.|:|||.:.|::.
 Frog    48 DLSPQYEVPGEGQQEREQWGKKIDFLLSVVGFSVDLANVWRFPFLCYKNGGGAFLIPYTLFLIIA 112

  Fly    68 GRPVYYLEISLGQFTGRGVVKAFDMAPLLKGVALGQVLATAASITYYSSIMALTLRFWLASFGSE 132
            |.|::|:|::|||:...|....:.:.||.|||....:|.......||:.|:|.:|.:.::||.||
 Frog   113 GMPLFYMELALGQYNREGAATVWKICPLFKGVGYTVILIALYVGFYYNVIIAWSLYYLVSSFTSE 177

  Fly   133 LPWSRCWESWGT-DCHDG----------NAQNSSGKMSPAQLYFEREILH-EVPNIDNGLSLPNW 185
            |||.:|...|.: :|.|.          |.:.|..|.:||..::||.:|| ...|..:.|..|.|
 Frog   178 LPWIKCGNEWNSLNCTDPMLLNMSMISYNTKYSKFKTTPAAEFYERGVLHLHESNGIHDLGQPRW 242

  Fly   186 QLVACLAIAWLVIGGVLIRGIKSSGKAAYFLGVFPYVVLLILLLRAVTLPGAIDGIIYFFKPQWR 250
            ||..||.:..:|:...|.:|:|:|||..:.....|||||.:||:|.:||||:..||..:.....:
 Frog   243 QLTICLIVVLIVLFFSLWKGVKTSGKVVWITATLPYVVLFVLLIRGITLPGSSKGISAYLHIDIK 307

  Fly   251 ELLNPLVWYAAVTQVFFSLAICFGTLITYASYNNFNRNVYNDIVIITTMDSCSSIIAGCITFGIL 315
            .|.:..||..|.||:|:||...||.||.:||||.|:.|.|.|.::.:|::..:|.|:|...|.||
 Frog   308 RLTDASVWIDAATQIFYSLGAGFGVLIAFASYNKFDNNCYRDALMTSTINCVTSFISGFAIFSIL 372

  Fly   316 GNLARETGNPDIGSVVKGGAGLAFISYPEAIAKFEYVPQMFAVLFFLMLFVLGIGSTVGMGSCIL 380
            |.:|.: .|.:|..|...||||.||.|||||:... ....:||:||:||..|||.|.:|....::
 Frog   373 GYMAHK-HNVNIEDVATEGAGLVFIIYPEAISTLA-GSTFWAVVFFIMLLTLGIDSAMGGMEAVI 435

  Fly   381 RVIRDQFGL--RSPPIWKLASGLTVLGFSVSIVYMTPGGQFILNLVDFYGVSFTALILAIGELVA 443
            ..:.|...:  |...::.|.  :..:.|..:::.:|.||.::|.|:|.:....:.|...:.|.:.
 Frog   436 TGLADDISILKRHRKLFTLL--VAFITFIFALLCITNGGIYVLTLLDTFAAGTSILFAVLIEAIG 498

  Fly   444 VAWIYGVNRFCEDIKFMMGIETGWYWRLCWRFITPGLMTAVLIYMLLDMSALEYKGVGYPTLAHV 508
            |:|.|||:||.|||..|:|...|.||||||:|::|..:..|:|..::....|.|....:|..|:.
 Frog   499 VSWFYGVDRFSEDIHRMLGFRPGLYWRLCWKFVSPAFLLFVVIVSIVTYKPLMYDEYKFPPWANR 563

  Fly   509 FGCFLATLGLIQLPGWAIYAIYKKRGHNGSFWQRIRAACKPSD 551
            .|..:|...:..:|   ||.|||.....||..:|:.....|.:
 Frog   564 TGWAIALSSMTLVP---IYIIYKFLTMRGSLRERLAYCITPEN 603

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
List	NP_611364.2	SLC6sbd	19..489	CDD:271359	182/483 (38%)
slc6a2	XP_017948962.2	SLC5-6-like_sbd	63..622	CDD:382020	198/548 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010