Protein Alignment List and slc6a15

DIOPT Version :10

• Sequence 1: NP_611364.2
• Gene: List / 37157
• FlyBaseID: FBgn0034381
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: XP_002931668.1
• Gene: slc6a15 / 100380162
• XenbaseID: XB-GENE-975885
• Length: 730
• Species: Xenopus tropicalis
• Alignment Length: 594
• Identity: 187/594 - (31%)
• Similarity: 304/594 - (51%)
• Gaps: 96/594 - (16%)

  Fly     5 EISKKSEKPAEKPAEQWGNGLEFLFSCISLSVGLGNIWRFPYIAFQNGGGTFVIPYLIALLVIGR 69
            :|.:.|:...|:||  |.:.|:::.:.:..||||||:|||||:..:||||.:::||||.||:||.
 Frog    50 DIEEGSDIDDERPA--WNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLVPYLILLLLIGI 112

  Fly    70 PVYYLEISLGQFTGRGVVKAFD-MAPLLKGVALGQVLATAASITYYSSIMALTLRFWLASFGSEL 133
            ||::||:|:||...||.:..:: ::|.:.|:.....:.......||:.|:..:|.::..||...|
 Frog   113 PVFFLELSVGQRIRRGSIGVWNYISPKMGGIGFASCIVCLFVALYYNVIIGWSLFYFSQSFQHPL 177

  Fly   134 PWSRCWESWGTDCHDGNAQNSSG--------KMSPAQLYFEREILHEVPNIDNGLSLPNWQLVAC 190
            ||.:|          ...:|:|.        |.|....|:.||.|:...:|..|..| ||::..|
 Frog   178 PWDQC----------PLVKNASNTFVEPECEKSSATTYYWYREALNISNSITEGGGL-NWKMTLC 231

  Fly   191 LAIAWLVIGGVLIRGIKSSGKAAYFLGVFPYVVLLILLLRAVTLPGAIDGIIYFFKPQWRELLNP 255
            |..||:::...:|:||:||||..||..:||||||...|:||:.|.|::|||.:.|.|:...:|.|
 Frog   232 LLAAWILVCLAMIKGIQSSGKVMYFSSLFPYVVLTCFLVRALLLNGSVDGIRHMFTPKLEIMLEP 296

  Fly   256 LVWYAAVTQVFFSLAICFGTLITYASYNNFNRNVYNDIVIITTMDSCSSIIAGCITFGILGNLAR 320
            .||..|.|||||:|.:.||.:|.::|||..:.|.:.|.|:::.::..:|::|..:.|.:||..|.
 Frog   297 KVWREAATQVFFALGLGFGGVIAFSSYNKRDNNCHFDAVLVSFINFFTSVLATLVVFAVLGFKAN 361

  Fly   321 ------------------ETGNPDIGSV-----------------------VK------------ 332
                              |.||....:|                       :|
 Frog   362 IMNENCISKNTVKIVKYLEAGNLSWSNVPHHVNFSSMSAQDYNLVYYIFQKIKEEEFDSLGLDSC 426

  Fly   333 ----------GGAGLAFISYPEAIAKFEYVPQMFAVLFFLMLFVLGIGSTVGMGSCILRVIRDQF 387
                      .|.|||||::.||:..|...| .::|:|||||..||:||..|....|:..|.|.|
 Frog   427 QIEDELNKSVQGTGLAFIAFTEAMTHFPASP-FWSVMFFLMLVNLGLGSMFGTIEGIITPIVDTF 490

  Fly   388 GLRSPPIWKLASGLTVLGFSVSIVYMTPGGQFILNLVDFYGVSFTALILAIGELVAVAWIYGVNR 452
            .:|..|   |..|..:|.|.:.::::...|.:.:.:.|.|..:...||:.|.|.||:||:||:::
 Frog   491 KVRKEP---LTVGCCLLAFCIGLLFVQRSGNYFVTMFDDYSATLPLLIVVILENVAIAWVYGIDK 552

  Fly   453 FCEDIKFMMGIETGWYWRLCWRFITPGLMTAVLIYMLLDMSALEYKGVGYPTLAHVFGCFLATLG 517
            |.:|:|.|:|.....|:...|::|:|.|:|.:|:..::.|.   :...||    :.:....|:..
 Frog   553 FMDDLKDMLGFTPYKYYYYMWKYISPVLLTILLMASIVQMG---FSPPGY----YAWIAEKASEE 610

  Fly   518 LIQLPGWAI 526
            .|..|.|.:
 Frog   611 RISYPPWGL 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
List	NP_611364.2	SLC6sbd	19..489	CDD:271359	175/541 (32%)
slc6a15	XP_002931668.1	SLC5-6-like_sbd	61..640	CDD:444915	184/583 (32%)