Protein Alignment List and slc6a19a.2

DIOPT Version :9

• Sequence 1: NP_611364.2
• Gene: List / 37157
• FlyBaseID: FBgn0034381
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: XP_002665492.2
• Gene: slc6a19a.2 / 100334171
• ZFINID: ZDB-GENE-141210-16
• Length: 647
• Species: Danio rerio
• Alignment Length: 630
• Identity: 195/630 - (30%)
• Similarity: 321/630 - (50%)
• Gaps: 112/630 - (17%)

  Fly     1 MTQLEISKKSEKPAEKPAEQWGNGLEFLFSCISLSVGLGNIWRFPYIAFQNGGGTFVIPYLIALL 65
            :.:||:.:..|:|      :|.|..:::.:|:...|||||:|||||:...:|||.|:||:||.|:
Zfish    22 LEKLELQEAGERP------KWDNKAQYMLTCVGFCVGLGNVWRFPYLCQSHGGGAFMIPFLILLV 80

  Fly    66 VIGRPVYYLEISLGQFTGRGVVKAF-DMAPLLKGVALGQVLATAASITYYSSIMALTLRFWLASF 129
            :.|.|:.:||.::||...||.|..: .:.|.|.||.:..:|.:.....||::|:|..:.::..||
Zfish    81 LEGIPLLHLEFAIGQRLRRGSVGVWRSINPYLLGVGIASMLVSFIVGMYYNTIIAWVMWYFFNSF 145

  Fly   130 GSELPWSRC-----WESWGTDCHDGNAQNSSGKMSPAQLYFEREILHEVPNIDNGLSLPNWQLVA 189
            ...||||:|     ...:.::|.         :.||...::.|:.|:..|:|::...| .|.:|.
Zfish   146 QDPLPWSQCPINGSRTGFVSECE---------RSSPVDYFWYRKTLNTTPHIEDSGGL-QWWMVL 200

  Fly   190 CLAIAWLVIGGVLIRGIKSSGKAAYFLGVFPYVVLLILLLRAVTLPGAIDGIIYFFKPQWRELLN 254
            .|..||.|:....||||:::|||.|.....||:||.|.|:|.:||.|::.||.:.|.|...|||:
Zfish   201 SLLCAWTVLWVCCIRGIETTGKAVYITSTLPYLVLTIFLIRGLTLKGSVSGIKFLFTPDVNELLD 265

  Fly   255 PLVWYAAVTQVFFSLAICFGTLITYASYNNFNRNVYNDIVIITTMDSCSSIIAGCITFGILGNLA 319
            |..|..|..|||||.::.||.||.::|||:.:.|...|.|||:.::..:||.|..:.:.|:|..|
Zfish   266 PQTWLDAGAQVFFSFSLAFGGLIAFSSYNSVHNNCEQDAVIISIINGMTSIYAAIVIYSIIGFRA 330

  Fly   320 RE------TGN----------PDIGSVVKG----------------------------------- 333
            .|      .||          |: ||:::|
Zfish   331 TERFDDCLNGNILSLLNAFDLPE-GSIIEGNYTEAIQQLNISRPDIIQELQLKTCDMQTFLSQGV 394

  Fly   334 -GAGLAFISYPEAIAKFEYVPQMFAVLFFLMLFVLGIGSTVGMGSCILRVIRDQFGLRSPPIW-- 395
             |.|||||.:.|||.|....| :::||||:|||.||:.:..|....::..::|...|  |..|
Zfish   395 EGTGLAFIVFTEAITKMPVSP-LWSVLFFIMLFCLGLSTMFGSIEGVVVPLQDLDIL--PKNWPK 456

  Fly   396 -KLASGLTVLGFSVSIVYMTPGGQFILNLVDFYGVSFTALILAIGELVAVAWIYGVNRFCEDIKF 459
             ...:.:.|:.|:.:|::....|::.|.|.|.:.||...||:|..|::||:::||::||.:||||
Zfish   457 EAYTALVCVVSFAFAIIFAQGSGEYWLALFDGFAVSIPLLIIAFCEMMAVSYVYGIDRFNDDIKF 521

  Fly   460 MMGIETGWYWRLCWRFITPGLMTAV-LIYMLLDMS------ALEYKGVGYPTL----------AH 507
            |:|.:...:|:..||.|:|.::..: |.|.:..:|      |.:.:...:|||          |.
Zfish   522 MIGHKPNIFWQATWRLISPLIVLVIFLFYFVTTVSKKLTYIAWDPESENFPTLSVLPYPGWISAI 586

  Fly   508 VFGCFLATLGLIQLPGWAIYAIYKKRGHNGSFWQRIRAACKPSDT 552
            :|  .||.:.::.:|..|:..:.:.|            .||..:|
Zfish   587 IF--ILAGIPVLVIPTVALVRLIRNR------------CCKKEET 617

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
List	NP_611364.2	SLC6sbd	19..489	CDD:271359	176/531 (33%)
slc6a19a.2	XP_002665492.2	SLC5-6-like_sbd	33..613	CDD:294310	189/613 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.900