Protein Alignment Vps51 and vps-51

DIOPT Version :9

• Sequence 1: NP_611363.2
• Gene: Vps51 / 37156
• FlyBaseID: FBgn0034380
• Length: 740
• Species: Drosophila melanogaster
• Sequence 2: NP_001020972.1
• Gene: vps-51 / 172247
• WormBaseID: WBGene00015176
• Length: 700
• Species: Caenorhabditis elegans
• Alignment Length: 754
• Identity: 192/754 - (25%)
• Similarity: 363/754 - (48%)
• Gaps: 98/754 - (12%)

  Fly    10 DMDSSSFDAEKYLERLLKDCSLKQIMDTEAAVVKDTQTLHSDMQTLVYENYNKFISATDTIRRMK 74
            |:....||.|.::.:||::.||..::..|..:|...:.|.||:..:||||||||::||:|:|:::
 Worm     6 DVTKPDFDVEAFVVKLLREKSLDGLVKEEEEMVSAVRRLDSDVHQIVYENYNKFLTATNTVRKIQ 70

  Fly    75 DDFKQMETDVNLLMTKMQSITTFSEQITGTLQGTRSQLCRLSEKHSLLKRLQFLSTLPAKLKSLI 139
            |:|.|:::::..|...|.:|:|....:.|.|...|..:.:|...:.::..|:.:..||..|:|..
 Worm    71 DEFTQLDSEMKSLSRSMSTISTLIGNLDGVLGEKRDDILQLGSSYKVVNSLKHIFDLPHVLRSEF 135

  Fly   140 EEQNYAQAVQDYLHAQKVFAQYGRQPSFDGIQRDCDAIMADLKEQLRSDFQRAGNTAQSLTEIGE 204
            :|:||.:.::.:..|::..:||...|:...:.:....|....:.||....:...:.|:.::|..:
 Worm   136 DERNYGEVLRMFKLAEESLSQYKDVPTVQLVLQKSKKIYDMTENQLMDQLRNPASGAELVSEAVD 200

  Fly   205 LLLQLDEKTSDLASEMLTCAGKRLHEQIVMLQDQTERDMLEFVDMGIDGFLNDLALVVTSYFDMF 269
            |||.:.....::...:|||:.:.|...:..| .....|:|:.||...:.|:.:|.|:.|::..:|
 Worm   201 LLLTIGRDEDEVQKVLLTCSEQSLRVDLKEL-SANHSDVLDLVDKASESFIPNLTLIATTHDRLF 264

  Fly   270 VAKHYEHERDDF------QENALQEL--NVFLNQNIEKYLTLVQDRVESDIGYGDTQVMLRALDR 326
                 |.:|:|.      :.|:|..|  .|||:.:..|                |..:::|||||
 Worm   265 -----EDKREDLITVLKTEMNSLHALVSKVFLSSSDAK----------------DCSIVVRALDR 308

  Fly   327 LHRRLQAMRNICRGLEVQRNTVSIIISAAHQLCDAHAKNLKDHFADSLSAVRLSLVSAKSDAAAG 391
            ..|::...|.:..||:....|:.:|.:.:....|.....:|:...:.|:.||.:|::.:.|.:|
 Worm   309 YFRKISTCRYVIPGLDFLPLTIELINAVSKHEIDLSLTRIKEELKNGLNEVRKALINEEKDLSA- 372

  Fly   392 LNLGDLISNLYVSMVEKIKGVLQDLLIFLRTDWSF-NIKAEHKGALCVEGIRENLLIGFLRHIAK 455
                 |.|.:....|.::|..|.:||:|..:|.:| |:..:...........|.||:......::
 Worm   373 -----LASKIEQVFVHQVKTALANLLLFTASDVTFANLPPDEFRQSFSFNAHERLLVQAFHRFSE 432

  Fly   456 VM----CGFGDASSSSPPNLLLVLSKTCLELEQQGVHILIALVDDLYEIDSENSATLTHETEICA 516
            :.    .|.|:..... |.:.||.:.....|..:....|:.|..:.:.:..::.  ||..|.:.:
 Worm   433 LADEYESGAGEIRFVD-PRVHLVFAVALQHLSNKSAVYLLNLCREQFSLSPDDG--LTDITVVMS 494

  Fly   517 EMRETAQSLLDAYVRLQGTNISQMLRKSVETRDWLNC-------LEPRSVRAVMKRVVEELGSIE 574
            |::..||.|:..|....|.::.:.|.|        .|       ..|.:|||.::|:|||:.:.:
 Worm   495 EVKTRAQKLVRCYAEKTGLSMGETLIK--------GCAMLVQPAATPSAVRASVRRLVEEMNTCD 551

  Fly   575 TVVASLYEANT----NATSGFRTTASSDSSRKTYFSNFASTSKPQYRSNWSNYTPSQLESSYVSN 635
            :.:..|...::    :..|....|.:.|::|.:
 Worm   552 SELTLLLGGDSKPKDSRVSRRPITTALDAARDS-------------------------------- 584

  Fly   636 IHRLFSERVEIFTSVEFTKASIIMGIIKIGLKTLLECVRLRTFSKFGLQQIQVDAHYLQMNLWRF 700
               |:.||::....:.|.:||||..|:|:.||..:|.:||:|:||||::|:|||.:|||..|...
 Worm   585 ---LWCERIDFHLQIHFNRASIITVIVKVVLKIFIESIRLQTYSKFGVEQVQVDCYYLQRCLAAL 646

  Fly   701 VSDENLVNFLLDEILGSAVQRCLESVLMEPNAVEIICER 739
            ||||.:||.::|:.|.||::||.:.||:.|:.:..:||:
 Worm   647 VSDEVVVNSMVDQALSSALKRCQDPVLVHPSRLAQLCEQ 685

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vps51	NP_611363.2	Vps51	11..95	CDD:400855	29/83 (35%)
		Dor1	51..210	CDD:418560	44/158 (28%)
vps-51	NP_001020972.1	Vps51	10..92	CDD:285862	30/81 (37%)
		Dor1	50..210	CDD:302817	43/159 (27%)
		DHQ_Fe-ADH	<193..247	CDD:295526	13/54 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166661
Domainoid	1	1.000	198	1.000	Domainoid score	I1806
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H34675
Inparanoid	1	1.050	264	1.000	Inparanoid score	I1879
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54424
OrthoDB	1	1.010	-	-		D1305393at2759
OrthoFinder	1	1.000	-	-		FOG0005127
OrthoInspector	1	1.000	-	-		oto19212
orthoMCL	1	0.900	-	-		OOG6_103074
Panther	1	1.100	-	-	LDO	PTHR15954
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2898
SonicParanoid	1	1.000	-	-		X4148
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.940