DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15073 and pzg

DIOPT Version :9

Sequence 1:	NP_611362.2	Gene:	CG15073 / 37155	FlyBaseID:	FBgn0034379	Length:	580	Species:	Drosophila melanogaster
Sequence 2:	NP_001262143.1	Gene:	pzg / 40351	FlyBaseID:	FBgn0259785	Length:	996	Species:	Drosophila melanogaster

Alignment Length:	351	Identity:	73/351 - (20%)
Similarity:	116/351 - (33%)	Gaps:	82/351 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   280 TDHIDRHADPEKFKCTQCDKRFADKQCLRNHELLKHHPEEEKTFMCEQCPKRYTKQYLLDQHRVI 344
            |..:.|.| .:.:|||.||.:.:|.:....|    :...:::||.|:.|.|.:.....:.||.|
  Fly   228 TQTVQRKA-TKIYKCTSCDYKTSDMRLFNTH----YETCKQQTFQCKTCRKIFPHFGAMKQHMV- 286

  Fly   345 HKERNV----VCDLCERRFPNQSLLCTHVKMAHGN------------------------------ 375
             ::.|.    .|.:|...|.|::.|..|::..|..
  Fly   287 -RDHNTAMDNTCAMCHINFVNENSLRKHMETNHATNVLVTSTTTIPASAAPVAAAAAAAAAAANE 350

  Fly   376 --YGT---MCDICAQVIRGRAAFQRHQLEHAGVTEPKVQCDICGSWHKNKHSLKKHVRRHNGTAA 435
              .||   .|:.|......:..|..|..:||.......:|.:|....:.:.:...|.::|.....
  Fly   351 NLVGTSLYTCNHCQFKSTDKVVFDEHMRKHAAGKPKPFKCRLCSQRFETREAATVHAKQHQTNFF 415

  Fly   436 TCDLCGKVSPNRSAMLSHQRYVHLTDRKHECSV---------CNKAFKKAI--TLREHMTMHTGE 489
            .|..|....|.|..::.|.. ||.:......|.         ..|..::.|  .|.:.:...|..
  Fly   416 KCGTCSMTFPKREMLVKHFE-VHQSPSASTVSPKQSVSQNLNTQKLLQETIDEALSDSLPASTAA 479

  Fly   490 VL-----------YKCPHCPKTFNS----NANQHTHRRKCHPKEFEEARKARTEKRKAIEEETPS 539
            |:           :.|..|..||..    |.:..||||  ..|.......|......|:..:.|.
  Fly   480 VVATTESENNIRFFSCSICSLTFIQETYYNHHMETHRR--DKKATSAGATALNSAATALLSDEPG 542

  Fly   540 VLTISTG-EDGESHSILLTNTEEDIK 564
            ..|...| |.||.      |.|.||:
  Fly   543 EATGKAGDESGEQ------NAEADIE 562

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15073	NP_611362.2	zf-AD	2..78	CDD:285071
		C2H2 Zn finger	269..286	CDD:275368	1/5 (20%)
		C2H2 Zn finger	294..316	CDD:275368	6/21 (29%)
		C2H2 Zn finger	325..345	CDD:275368	6/19 (32%)
		C2H2 Zn finger	352..370	CDD:275368	6/17 (35%)
		C2H2 Zn finger	410..430	CDD:275368	3/19 (16%)
		C2H2 Zn finger	437..458	CDD:275368	5/20 (25%)
		C2H2 Zn finger	466..486	CDD:275368	4/30 (13%)
		C2H2 Zn finger	494..512	CDD:275368	7/21 (33%)
pzg	NP_001262143.1	C2H2 Zn finger	241..263	CDD:275371	6/25 (24%)
		C2H2 Zn finger	268..289	CDD:275371	6/22 (27%)
		C2H2 Zn finger	297..318	CDD:275371	6/20 (30%)
		C2H2 Zn finger	360..380	CDD:275368	4/19 (21%)
		zf-H2C2_2	373..399	CDD:290200	6/25 (24%)
		zf-C2H2_8	375..443	CDD:292531	14/68 (21%)
		C2H2 Zn finger	390..410	CDD:275368	3/19 (16%)
		C2H2 Zn finger	417..437	CDD:275368	5/20 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24403
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100