DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15073 and Prdm13

DIOPT Version :9

Sequence 1:	NP_611362.2	Gene:	CG15073 / 37155	FlyBaseID:	FBgn0034379	Length:	580	Species:	Drosophila melanogaster
Sequence 2:	NP_648032.1	Gene:	Prdm13 / 38713	FlyBaseID:	FBgn0035687	Length:	465	Species:	Drosophila melanogaster

Alignment Length:	382	Identity:	72/382 - (18%)
Similarity:	113/382 - (29%)	Gaps:	152/382 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly   231 ISAHMRLTCDVCHEGQETFLLLCKHMLQEHHRKGYAICCNKKFYKRSFLTDHIDRHADPEKFKCT 295
            |..:.|..|.:||...||     .|.|:.|    .|:.|.:......::..|
  Fly   175 IQGNSRYMCHLCHLTFET-----PHPLKIH----LALGCGRSAMDILWMRLH------------- 217

  Fly   296 QCDKRFADKQCLRNHELLKHHPEEEKTFMCE---------QCPKRYTK----------------- 334
                 :|.|...|:|...:|.|....:....         |.|.|::.
  Fly   218 -----YALKAAARSHTETQHSPIPATSSTSSASPTHSPPPQMPPRFSAFRPIAALTQSLPMVPVT 277

  Fly   335 ------QYLLDQHRVIHKERNVVCDLCERRFPNQSL----LCTH------------VKMAHGNYG 377
                  .||                      |:.|:    |.|:            ..|.....|
  Fly   278 TAATPLSYL----------------------PSMSMATAPLSTNPMNAAAQIEAIVSNMGASKQG 320

  Fly   378 TMCDICAQVIRGRAAFQRHQLEHAGVTEPKVQCDICGSWHKNKHSLKKHVRRH------------ 430
            .:|..|.:|...:...:.|...|.|. :| ::|..|.....:..:|.||||.|
  Fly   321 HLCIYCGKVYSRKYGLKIHIRTHTGF-KP-LKCKFCLRPFGDPSNLNKHVRLHLQTHPSSSAGVA 383

  Fly   431 NGTAATCDLCGKVSPNRSAMLSHQRYVHLTDRKHECSVCNKAFKKAITLREHM-TMHTGEVLYKC 494
            :|.|:..|:.|.|.....           ||..::|.||:|:|.:...|:.|| |.|.|.
  Fly   384 DGGASGADMDGDVDIEGE-----------TDADYQCHVCHKSFPRRRDLQRHMETRHGGH----- 432

  Fly   495 PHCPKTFNSNANQHTHRRKCHPKEFEEARKARTEKRKAIEEETPSVLTISTGEDGES 551
                       :.|:|         .|:|.:.|    :....|....|::|.....|
  Fly   433 -----------HSHSH---------SESRSSST----STSSTTTMTATVTTSTSKSS 465

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15073	NP_611362.2	zf-AD	2..78	CDD:285071
		C2H2 Zn finger	269..286	CDD:275368	2/16 (13%)
		C2H2 Zn finger	294..316	CDD:275368	4/21 (19%)
		C2H2 Zn finger	325..345	CDD:275368	5/51 (10%)
		C2H2 Zn finger	352..370	CDD:275368	4/33 (12%)
		C2H2 Zn finger	410..430	CDD:275368	7/19 (37%)
		C2H2 Zn finger	437..458	CDD:275368	3/20 (15%)
		C2H2 Zn finger	466..486	CDD:275368	9/20 (45%)
		C2H2 Zn finger	494..512	CDD:275368	2/17 (12%)
Prdm13	NP_648032.1	COG5048	280..>380	CDD:227381	23/123 (19%)
		C2H2 Zn finger	323..343	CDD:275368	4/19 (21%)
		zf-H2C2_2	336..358	CDD:290200	6/23 (26%)
		C2H2 Zn finger	351..371	CDD:275368	7/19 (37%)
		zf-C2H2	406..427	CDD:278523	8/20 (40%)
		C2H2 Zn finger	408..427	CDD:275368	8/18 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24403
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100