DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15073 and Zfp513

DIOPT Version :9

Sequence 1:	NP_611362.2	Gene:	CG15073 / 37155	FlyBaseID:	FBgn0034379	Length:	580	Species:	Drosophila melanogaster
Sequence 2:	NP_001012110.1	Gene:	Zfp513 / 313913	RGDID:	1310456	Length:	541	Species:	Rattus norvegicus

Alignment Length:	505	Identity:	101/505 - (20%)
Similarity:	158/505 - (31%)	Gaps:	138/505 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    93 GEDSEQQEEEQDEDQELGLPGSEGGSFTNEQFLTEVIAQQEQQTDS---NPPKEQFIKEDN---- 150
            |:|.|.:|||::|:          |...|:|.:.   .:::.:.||   .|.....:.:|.
  Rat    41 GQDLEFEEEEEEEE----------GDGHNDQLMG---FERDSEGDSQGARPGLPYGLSDDESGGG 92

  Fly   151 ---ATVNDPETSATLPTEQRRETRSTAKSKAHHSLPPSTPPEKSNSVANKSKAKRTPCKAEGTPQ 212
               :..::.|..|..|.|.|.|.             |....:.......:.     ||...|.|.
  Rat    93 RALSAESEVEEPARGPGEARGER-------------PGPACQLCGGPTGEG-----PCCGAGGPG 139

  Fly   213 KSKRYADYKQCMLDIDAKISAHMRLTCDVCHEGQETFLLLCKHMLQEHHRKGYAICCNKKFYKRS 277
            ...          .:..::....||...|.|....    |.:||......|.:.  |.:..|..:
  Rat   140 GGP----------PLPPRLLYSCRLCAFVSHYSSH----LKRHMQTHSGEKPFR--CGRCPYASA 188

  Fly   278 ---FLTDHIDRHADPEKFKCTQCDKRFADKQCLRNHELLKHHPEEEKTFMCEQC----------- 328
               .||.|...|...:.::|..|....:....||.|:.....|   .|..|..|
  Rat   189 QLVNLTRHTRTHTGEKPYRCPHCPFACSSLGNLRRHQRTHTGP---PTPPCPTCGFRCCAPRPTR 250

  Fly   329 -----------PKRYTKQYLLDQHRV---------------IHKERNVVC-----DLCERRFP-- 360
                       |:|.....:|....:               :..|...:|     .|.|..||
  Rat   251 PPSPTEQEGTMPRRSEDALILPDLSLHVPPGGTSFLPDCGQLRGEGEGLCGTGSEPLPELLFPWT 315

  Fly   361 ----NQSL--------------LCTHVKMAHG---------NYGTMCDICAQVIRGRAAFQRHQL 398
                .|.|              .|...:...|         :.|..|.:|...........||..
  Rat   316 CRGCGQELEEGEGSRLGTAMCGRCMRGESGGGGSGGPQGPSDKGFACSLCPFATHYPNHLARHMK 380

  Fly   399 EHAGVTEPKVQCDICGSWHKNKHSLKKHVRRHNGTAA-TCDLCGKVSPNRSAMLSHQRYVHLTDR 462
            .|:|  |...:|..|.....:..:||:|.|.|.|... .|.||.....|.:.:..|.| :|..|:
  Rat   381 THSG--EKPFRCARCPYASAHLDNLKRHQRVHTGEKPYKCPLCPYACGNLANLKRHGR-IHSGDK 442

  Fly   463 KHECSVCNKAFKKAITLREHMTMHTGEVLYKCPHCPKTFNSNANQHTHRR 512
            ...||:||.:..:::.|:.||..||||..::|..|..|.....|...|::
  Rat   443 PFRCSLCNYSCNQSMNLKRHMLRHTGEKPFRCATCAYTTGHWDNYKRHQK 492

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15073	NP_611362.2	zf-AD	2..78	CDD:285071
		C2H2 Zn finger	269..286	CDD:275368	5/19 (26%)
		C2H2 Zn finger	294..316	CDD:275368	5/21 (24%)
		C2H2 Zn finger	325..345	CDD:275368	5/56 (9%)
		C2H2 Zn finger	352..370	CDD:275368	8/42 (19%)
		C2H2 Zn finger	410..430	CDD:275368	6/19 (32%)
		C2H2 Zn finger	437..458	CDD:275368	6/20 (30%)
		C2H2 Zn finger	466..486	CDD:275368	7/19 (37%)
		C2H2 Zn finger	494..512	CDD:275368	5/17 (29%)
Zfp513	NP_001012110.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..120		21/104 (20%)
		C2H2 Zn finger	152..172	CDD:275368	7/23 (30%)
		zf-H2C2_2	164..189	CDD:290200	6/30 (20%)
		COG5048	176..>228	CDD:227381	12/53 (23%)
		C2H2 Zn finger	180..200	CDD:275368	5/19 (26%)
		zf-H2C2_2	192..217	CDD:290200	6/24 (25%)
		C2H2 Zn finger	208..228	CDD:275368	5/19 (26%)
		C2H2 Zn finger	362..382	CDD:275368	4/19 (21%)
		COG5048	<372..>450	CDD:227381	23/80 (29%)
		zf-H2C2_2	374..399	CDD:290200	7/26 (27%)
		C2H2 Zn finger	390..410	CDD:275368	6/19 (32%)
		zf-H2C2_2	402..425	CDD:290200	9/22 (41%)
		COG5048	414..>487	CDD:227381	22/73 (30%)
		C2H2 Zn finger	418..438	CDD:275368	6/20 (30%)
		C2H2 Zn finger	446..466	CDD:275368	7/19 (37%)
		zf-H2C2_2	458..481	CDD:290200	9/22 (41%)
		C2H2 Zn finger	474..493	CDD:275368	5/19 (26%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	492..541		0/1 (0%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24403
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100