DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG15073 and ZNF652

DIOPT Version :9

Sequence 1:NP_611362.2 Gene:CG15073 / 37155 FlyBaseID:FBgn0034379 Length:580 Species:Drosophila melanogaster
Sequence 2:NP_001138837.1 Gene:ZNF652 / 22834 HGNCID:29147 Length:606 Species:Homo sapiens


Alignment Length:486 Identity:120/486 - (24%)
Similarity:180/486 - (37%) Gaps:118/486 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    67 AVESAHRLLTERFSLKSGQDQGKVEHGEDSEQQEEEQDEDQELGLPGSEGGSFTNEQFLTEV--- 128
            ||...|.:..:|            |:.:|:|::|||.              |:..||.:.||   
Human    86 AVSDVHAVKEDR------------ENSDDTEEEEEEV--------------SYKREQIIVEVNLN 124

  Fly   129 ------------IAQQEQQT---DSNPPKEQFIKEDNAT--VND--------------PETSATL 162
                        ::.|.::|   .::..:|:...|:.||  .||              .:.|.| 
Human   125 NQTLNVSKGEKGVSSQSKETPVLKTSSEEEEEESEEEATDDSNDYGENEKQKKKEKIVEKVSVT- 188

  Fly   163 PTEQRRETRSTAKSKAHHSLPPSTPPEKSNSVANKSKAKRTPCKAEGTPQKSKRYADYKQCMLDI 227
               |||..|:.:.:.|..|..|.|...:..||....:.||...:.:...||              
Human   189 ---QRRTRRAASVAAATTSPTPRTTRGRRKSVEPPKRKKRATKEPKAPVQK-------------- 236

  Fly   228 DAKISAHMRLTCDVCHEGQETFLLLCKHMLQEHHRKGYAICCNKKFYKRSFLTDHIDRHADPEK- 291
             ||......|||:.|.....|...|.|||...|.|......|.|||...|.|:.|  :..|.|| 
Human   237 -AKCEEKETLTCEKCPRVFNTRWYLEKHMNVTHRRMQICDKCGKKFVLESELSLH--QQTDCEKN 298

  Fly   292 FKCTQCDKRFADKQCLRNHELLK-HHPEEEKTFMCEQCPKRYTKQYLLDQHRVIH-KERNVVCDL 354
            .:|..|:|.|  |:....||.:| .|...||.|.||.|.|::.....:.:|.|.| |:....|:.
Human   299 IQCVSCNKSF--KKLWSLHEHIKIVHGYAEKKFSCEICEKKFYTMAHVRKHMVAHTKDMPFTCET 361

  Fly   355 CERRFPNQSLLCTHVKMAHGNYGTMCDICAQVIRGRAAFQRHQLEHAGVTEPKVQCDICGSWHKN 419
            |.:.|.....|                            :.|.|:|:|  |...:|:.|....:.
Human   362 CGKSFKRSMSL----------------------------KVHSLQHSG--EKPFRCENCDERFQY 396

  Fly   420 KHSLKKHVRRHNG-TAATCDLCGKVSPNRSAMLSHQRYVHLTDRKHECSVCNKAFKKAITLREHM 483
            |:.|:.|:..|.| ....|..|||....:.....|.: .|..::...|.:|.|:|.....::.|.
Human   397 KYQLRSHMSIHIGHKQFMCQWCGKDFNMKQYFDEHMK-THTGEKPFICEICGKSFTSRPNMKRHR 460

  Fly   484 TMHTGEVLYKCPHCPKTFNSNANQHTHRRKC 514
            ..||||..|.|..|.:.|..:.....|:.||
Human   461 RTHTGEKPYPCDVCGQRFRFSNMLKAHKEKC 491

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG15073NP_611362.2 zf-AD 2..78 CDD:285071 3/10 (30%)
C2H2 Zn finger 269..286 CDD:275368 7/16 (44%)
C2H2 Zn finger 294..316 CDD:275368 8/22 (36%)
C2H2 Zn finger 325..345 CDD:275368 6/19 (32%)
C2H2 Zn finger 352..370 CDD:275368 4/17 (24%)
C2H2 Zn finger 410..430 CDD:275368 5/19 (26%)
C2H2 Zn finger 437..458 CDD:275368 5/20 (25%)
C2H2 Zn finger 466..486 CDD:275368 5/19 (26%)
C2H2 Zn finger 494..512 CDD:275368 4/17 (24%)
ZNF652NP_001138837.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 71..113 11/52 (21%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 130..235 22/108 (20%)
UFD1 <240..304 CDD:332114 22/65 (34%)
C2H2 Zn finger 247..266 CDD:275368 7/18 (39%)
C2H2 Zn finger 274..293 CDD:275368 7/20 (35%)
C2H2 Zn finger 301..321 CDD:275368 8/21 (38%)
C2H2 Zn finger 331..351 CDD:275368 6/19 (32%)
C2H2 Zn finger 359..379 CDD:275368 6/47 (13%)
SFP1 <381..464 CDD:227516 20/85 (24%)
C2H2 Zn finger 387..407 CDD:275368 5/19 (26%)
C2H2 Zn finger 415..435 CDD:275368 5/20 (25%)
COG5048 439..>488 CDD:227381 13/48 (27%)
C2H2 Zn finger 443..463 CDD:275368 5/19 (26%)
C2H2 Zn finger 471..487 CDD:275368 3/15 (20%)
Mediates interaction with CBFA2T3. /evidence=ECO:0000269|PubMed:16966434 498..606
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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