Protein Alignment CG15073 and znf462

DIOPT Version :10

• Sequence 1: NP_611362.2
• Gene: CG15073 / 37155
• FlyBaseID: FBgn0034379
• Length: 580
• Species: Drosophila melanogaster
• Sequence 2: XP_002934034.2
• Gene: znf462 / 100492944
• XenbaseID: XB-GENE-976911
• Length: 2458
• Species: Xenopus tropicalis
• Alignment Length: 745
• Identity: 139/745 - (18%)
• Similarity: 229/745 - (30%)
• Gaps: 251/745 - (33%)

  Fly    47 STVICLTCWNQVNDFHQFYVAVESAH---RLLTERFSLKSGQDQGKVE------------HG--- 93
            |..:|..|.::.|:.|.........|   ::....|:.:...:.|.|.            ||
 Frog  1382 SPYLCTVCHSEYNNLHGLLTHYGKKHPGMKVKAADFAQEVDINPGAVYKCRHCPYINTRIHGVLT 1446

  Fly    94 ---------------------EDSEQQEEEQDEDQELGLPGSEGGSFT------NEQFLTEVIAQ 131
                                 :.:|..:.|.||:..:...|.  |::.      ....|.::...
 Frog  1447 HYQKRHPSVKVTAEDFVHDVEQSTEMSQNESDENSRIFKQGY--GAYRCKICPYTHGTLEKLKIH 1509

  Fly   132 QEQQTDSNPPKEQFIKEDNATV--------NDPETSATL-------PTEQRRETR---------- 171
            .|:..|...|......:|.|:|        :.|:|..||       ||:.:|...
 Frog  1510 YEKYHDQPEPDMLSSPKDFASVETDVLLDEHPPQTVVTLEAAVVKGPTKYKRNHMAPHTVFRCQL 1574

  Fly   172 -----STAKSKAHHSLPPSTPPEKSNSVANKSKAKRTPCK---AEGTPQKSKRYADYKQCMLDID 228
                 ||.|..|.|.      ..|.|:|..:.:.|....|   ...|....|..|.:.|...|||
 Frog  1575 CKYFCSTRKGIARHY------RIKHNNVRAQPEGKNNLFKCALCSYTNPIRKGLAAHYQKRHDID 1633

  Fly   229 AKIS---AHMRLTCD------VCHEGQETFLLLCKHMLQEHHRKGYAICCNKKFYKRSFLTDHID 284
            |..:   |..|...|      :....::..|.|.:.:.:....|..::|..:.:.|:..:|.::.
 Frog  1634 AYYTHCLAASRTVSDKPNKVVIPSPQKDDSLELSEELKKAVEMKKCSLCSFQSYSKKGIVTHYMK 1698

  Fly   285 RH-----------------------------------ADPE-------KFKCTQCDK-RFADKQC 306
            ||                                   .:||       .|:|.:|.| .|:..:.
 Frog  1699 RHPGVFPKKQYGSKLGNYFTTVYAEENEQPATEEATETEPEPQEQELLPFRCIKCFKLSFSTAEL 1763

  Fly   307 LRNHELLKHHPEEEK----------------TFMCEQC---------------------PKRYTK 334
            |..| ...||.::.|                |:.|:.|                     .||..:
 Frog  1764 LCMH-YTDHHSKDIKRDFSVLGTSGTRSLTTTYQCKHCNSKLNSVADLTIHLNAHNEDFQKRAKR 1827

  Fly   335 Q----YLLDQHRV---------------IH---KERNVV---CDLCERRFPNQSLLCTHVKMAHG 374
            |    .||::.::               :|   ||:.||   |..|....|....:|.|:: .|.
 Frog  1828 QERRKQLLNKQKLTEIAENKEKMGNEAALHKSCKEKAVVGYKCKFCVEVHPTLRAICNHLR-KHV 1891

  Fly   375 NYGTMCDICAQVIRGRAAF-----------------QRHQLEHAG-------VTEPK-------- 407
            .||.:.::.:.:...:..|                 :...:|.|.       |.|.|
 Frog  1892 QYGNVPELSSDLQDEKYEFTDEDTIEYDYDDGVDDEEEEDVEEASTPAEENPVDEAKETKKGRRT 1956

  Fly   408 ----VQCDICGSWHKNKHSLKKHVRRHNGTAA-------TCDLCGKVSPNRSAMLSHQRYVHLTD 461
                ..|..|.....:...|:.|.|.|...|.       :|..|..||..|..:..|.:..|...
 Frog  1957 RPGGYPCKQCDRVLMSMQGLRSHERSHLALAMFTRDDKYSCQFCSFVSAFRHNLDRHVQTHHGHH 2021

  Fly   462 RKHECSVCNKAFKKAIT--LREH-MTMHTGEVLYKCPHCPKTFNSNANQHTHRRKCHPKEFEEAR 523
            :...|.:|  .||.:..  |:.| |..|.||..|||..||.:..:.:....|..|.|.|.....|
 Frog  2022 KPFRCKLC--PFKSSYNSRLKTHIMKAHAGEHAYKCSFCPFSTMTISQLKDHSLKVHGKTLTLPR 2084

  Fly   524 KARTEKRKAIEEETPSVLTISTGEDGESHS 553
             .||..:.:...:..:.:...:|.|..|:|
 Frog  2085 -IRTISQTSPRAKQTTRIGKESGLDDSSYS 2113

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15073	NP_611362.2	zf-AD	2..75	CDD:462262	6/30 (20%)
		COG5236	<240..>375	CDD:227561	40/245 (16%)
		C2H2 Zn finger	269..286	CDD:275368	2/16 (13%)
		C2H2 Zn finger	294..316	CDD:275368	6/22 (27%)
		C2H2 Zn finger	325..345	CDD:275368	7/59 (12%)
		C2H2 Zn finger	352..370	CDD:275368	5/17 (29%)
		C2H2 Zn finger	410..430	CDD:275368	5/19 (26%)
		C2H2 Zn finger	437..458	CDD:275368	6/20 (30%)
		C2H2 Zn finger	466..486	CDD:275368	7/22 (32%)
		C2H2 Zn finger	494..512	CDD:275368	4/17 (24%)
znf462	XP_002934034.2	C2H2 Zn finger	1963..1983	CDD:275370	5/19 (26%)
		C2H2 Zn finger	1997..2017	CDD:275368	6/19 (32%)
		C2H2 Zn finger	2026..2047	CDD:275368	7/22 (32%)
		C2H2 Zn finger	2055..2076	CDD:275368	5/20 (25%)
		C2H2 Zn finger	2221..2241	CDD:275368
		C2H2 Zn finger	2267..2287	CDD:275368