Protein Alignment Sik3 and CIPK18

DIOPT Version :10

• Sequence 1: NP_611361.4
• Gene: Sik3 / 37152
• FlyBaseID: FBgn0262103
• Length: 1471
• Species: Drosophila melanogaster
• Sequence 2: NP_174217.1
• Gene: CIPK18 / 839797
• AraportID: AT1G29230
• Length: 520
• Species: Arabidopsis thaliana
• Alignment Length: 355
• Identity: 136/355 - (38%)
• Similarity: 197/355 - (55%)
• Gaps: 29/355 - (8%)

  Fly    18 TPQNYKVPSTSKISVDKLLRVGYYELEKTIGKGNFAVVKLATNIVTKTKVAIKIIDKTCLNEEYL 82
            :||:.:.|.:.:.::    .:|.|||.|.:|.|.||.|.||.||.:..|||||:|||..:.:..|
plant    55 SPQSPRSPRSPRNNI----LMGKYELGKLLGHGTFAKVYLAQNIKSGDKVAIKVIDKEKIMKSGL 115

  Fly    83 NKTF-REIAILKSLRHPHITRLYEVMESQSMIYLVTEYAPNGEIFDHLVANGRMKEPEAARVFTQ 146
            .... |||:||:.:|||:|..|:|||.::|.||.|.||...||:| :.||.||:.|..|.|.|.|
plant   116 VAHIKREISILRRVRHPYIVHLFEVMATKSKIYFVMEYVGGGELF-NTVAKGRLPEETARRYFQQ 179

  Fly   147 LVSAVHYCHRRGVVHRDLKAENVLLDKDMNIKLADFGFS---NHYEEGATLKTWCGSPPYAAPEV 208
            |:|:|.:||.|||.|||||.||:|||...|:|::|||.|   ....:.....|:||:|.|.||||
plant   180 LISSVSFCHGRGVYHRDLKPENLLLDNKGNLKVSDFGLSAVAEQLRQDGLCHTFCGTPAYIAPEV 244

  Fly   209 FQGLEYDGPKSDIWSLGVVLYALVCGALPFDGKTILELKSRVVLGKFRIPFFMSQECEQLIRNML 273
            .....||..|:|:||.||:|:.|:.|.:||..|.|:.:..::..|:||.|.:.|.:..:|:..:|
plant   245 LTRKGYDAAKADVWSCGVILFVLMAGHIPFYDKNIMVMYKKIYKGEFRCPRWFSSDLVRLLTRLL 309

  Fly   274 VVEPDRRYTIKQIIKHRWLSEWQS-------------EMQEQERFGDMSPGSGTVSKSAS---TS 322
            ...||.|.||.:|:|:||..:...             |.:::|.....|..|.|||:|.:   ..
plant   310 DTNPDTRITIPEIMKNRWFKKGFKHVKFYIEDDKLCREDEDEEEEASSSGRSSTVSESDAEFDVK 374

  Fly   323 SLGSASDSPPQ----LDSVVMTHMLQLPGL 348
            .:|..|...|.    .|.:..:....|.||
plant   375 RMGIGSMPRPSSLNAFDIISFSSGFDLSGL 404

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sik3	NP_611361.4	Protein Kinases, catalytic domain	40..292	CDD:473864	116/255 (45%)
		UBA_SIK	335..380	CDD:270523	4/14 (29%)
CIPK18	NP_174217.1	Protein Kinases, catalytic domain	73..327	CDD:473864	115/254 (45%)
		CIPK_C	388..499	CDD:213380	4/17 (24%)