Protein Alignment Sik3 and CIPK12

DIOPT Version :10

• Sequence 1: NP_611361.4
• Gene: Sik3 / 37152
• FlyBaseID: FBgn0262103
• Length: 1471
• Species: Drosophila melanogaster
• Sequence 2: NP_193605.1
• Gene: CIPK12 / 827604
• AraportID: AT4G18700
• Length: 489
• Species: Arabidopsis thaliana
• Alignment Length: 533
• Identity: 162/533 - (30%)
• Similarity: 247/533 - (46%)
• Gaps: 98/533 - (18%)

  Fly    13 PPTSSTPQNYKVPSTSKISVDKLLRVGYYELEKTIGKGNFAVVKLATNIVTKTKVAIKIIDK-TC 76
            |...|:||              .|.:|.||:.|.:|.|.||.|.||.|:.|...||||:||| ..
plant    12 PKERSSPQ--------------ALILGRYEMGKLLGHGTFAKVYLARNVKTNESVAIKVIDKEKV 62

  Fly    77 LNEEYLNKTFREIAILKSLRHPHITRLYEVMESQSMIYLVTEYAPNGEIFDHLVANGRMKEPEAA 141
            |....:....|||:||:.:|||:|.:|:|||.:::.||.|.||...||:|:. ||.||:||..|.
plant    63 LKGGLIAHIKREISILRRVRHPNIVQLFEVMATKAKIYFVMEYVRGGELFNK-VAKGRLKEEVAR 126

  Fly   142 RVFTQLVSAVHYCHRRGVVHRDLKAENVLLDKDMNIKLADFGF---SNHYEEGATLKTWCGSPPY 203
            :.|.||:|||.:||.|||.|||||.||:|||::.|:|::|||.   |:...:.....|:||:|.|
plant   127 KYFQQLISAVTFCHARGVYHRDLKPENLLLDENGNLKVSDFGLSAVSDQIRQDGLFHTFCGTPAY 191

  Fly   204 AAPEVFQGLEYDGPKSDIWSLGVVLYALVCGALPFDGKTILELKSRVVLGKFRIPFFMSQECEQL 268
            .||||.....||..|.||||.||:|:.|:.|.|||..:.::.:..::..|:||.|.:.|.|..:|
plant   192 VAPEVLARKGYDAAKVDIWSCGVILFVLMAGYLPFHDRNVMAMYKKIYRGEFRCPRWFSTELTRL 256

  Fly   269 IRNMLVVEPDRRYTIKQIIKHRWLSEWQSEMQ---EQERFGDMSPGSGTVSKSASTSSLGSASDS 330
            :..:|...|::|:|..:|:::.|..:....::   |.::..::.......|.|..:....:||:|
plant   257 LSKLLETNPEKRFTFPEIMENSWFKKGFKHIKFYVEDDKLCNVVDDDELESDSVESDRDSAASES 321

  Fly   331 ----------------PPQL---DSVVMTHMLQLPGLTADMIAQSVHEQRFDNIYAIYNLLHDKL 376
                            |..|   |.:..:....|.||..|    .....||.:...:..::
plant   322 EIEYLEPRRRVGGLPRPASLNAFDIISFSQGFDLSGLFDD----DGEGSRFVSGAPVSKII---- 378

  Fly   377 QQRRRENQRLQHHASLAYSRSRKTSITTGVVDRSEPVKQESLDRLSPLSNANASSSALGFGWSDV 441
                   .:|:..|.:.....||......:....:.||       .||:.|   :.......|.|
plant   379 -------SKLEEIAKVVSFTVRKKDCRVSLEGSRQGVK-------GPLTIA---AEIFELTPSLV 426

  Fly   442 AVDLEKYG----DFELECLARSNDPPVNAQHLSAHAGGGVNGANTRRHTVGPGDVAHE------- 495
            .|:::|.|    ::|..|   :|:.....|:|:|                  .||..|
plant   427 VVEVKKKGGDKTEYEDFC---NNELKPKLQNLTA------------------DDVVAEPVAVSAV 470

  Fly   496 QALANPNVPPIDF 508
            ...|.||.|.|.|
plant   471 DETAIPNSPTISF 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sik3	NP_611361.4	Protein Kinases, catalytic domain	40..292	CDD:473864	111/255 (44%)
		UBA_SIK	335..380	CDD:270523	7/44 (16%)
CIPK12	NP_193605.1	STKc_SnRK3	25..279	CDD:271133	111/254 (44%)
		CIPK_C	342..453	CDD:213380	24/138 (17%)