Protein Alignment Sik3 and Smok3c

DIOPT Version :9

• Sequence 1: NP_001188969.1
• Gene: Sik3 / 37152
• FlyBaseID: FBgn0262103
• Length: 1471
• Species: Drosophila melanogaster
• Sequence 2: NP_001297632.1
• Gene: Smok3c / 622486
• MGIID: 3647925
• Length: 504
• Species: Mus musculus
• Alignment Length: 403
• Identity: 127/403 - (31%)
• Similarity: 205/403 - (50%)
• Gaps: 47/403 - (11%)

  Fly    41 YELEKTIGKGNFAVVKLATNIVTKTKVAIKIIDKT---CLNEEYLNKTFREIAILKSLRHPHITR 102
            |.:.:|||.|..|.||||.:.:|.|.||:|.|.|.   |:      ....|:.:|....||::..
Mouse    28 YVMLETIGHGGCATVKLAQHRLTGTHVAVKTIQKRGYWCI------LIMSEVDLLMMADHPNVIS 86

  Fly   103 LYEVMESQSMIYLVTEYAPNGEIFDHLVANGRMKEPEAARVFTQLVSAVHYCHRRGVVHRDLKAE 167
            |.:|:|::..:||:.|......::.|:...|.::|.||..:|.||:||::|||.:|:||||||.:
Mouse    87 LLQVIETKKKVYLIMELCEGKSLYQHIRKAGYLQEHEARALFKQLLSAMNYCHNQGIVHRDLKPD 151

  Fly   168 NVLLDKDMNIKLADFGFSNHYEEGATLKTWCGSPPYAAPEVFQGLEYDGPKSDIWSLGVVLYALV 232
            |::::||..:|:.|||.|...:.|..|..:||:.|::||||.....|||||.|:|:||||||.:|
Mouse   152 NIMVEKDGKVKIIDFGLSTKVKPGQKLNLFCGTYPFSAPEVLLSTPYDGPKIDVWTLGVVLYFMV 216

  Fly   233 CGALPFDGKTILELKSRVVLGKFRIPFFMSQECEQLIRNMLVVEPDRRYTIKQIIKHRWLSEWQS 297
            .|.:|||..:|..|..|::.||:.||..:|.|...|:..::...|..|.|:.:::.|.|::|
Mouse   217 TGKIPFDACSIKRLVKRILAGKYSIPSRLSAELRDLLSLLMTANPKLRPTVAEVMVHPWVTE--- 278

  Fly   298 EMQEQERFGDMSPGSGTVSKSASTSSLGSASDSPPQLDSVVMTHMLQLPGLTADMIAQSVHEQRF 362
                         |||.......       ..:|.:.|..::..|..: |..|..|..|:.:::|
Mouse   279 -------------GSGVFPDPCE-------EQTPLKPDPAIVKAMGHI-GFQAQDIEDSLRQRKF 322

  Fly   363 DNIYAIYNLLHDKLQQRRRENQRLQHHASLAYSRSRKTSIT--TGVVDRSEP---VKQESLDRLS 422
            :...|.|.||         :.|.|:.......:|....|:|  ..:||.:..   :::...:...
Mouse   323 NQTMASYCLL---------KKQILKECDRPTRARPVNPSVTPFPSLVDTATTCLGLRRRENEPTC 378

  Fly   423 PLSNANASSSALG 435
            |.|:||...|..|
Mouse   379 PWSSANRQVSVCG 391

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sik3	NP_001188969.1	PKc_like	40..292	CDD:304357	97/253 (38%)
		S_TKc	41..292	CDD:214567	97/253 (38%)
		UBA_SIK	335..380	CDD:270523	11/44 (25%)
Smok3c	NP_001297632.1	STKc_AMPK-like	27..275	CDD:270905	97/252 (38%)
		UBA_MARK_Par1	295..334	CDD:270522	11/48 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0586
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810